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Browse our anti-PCNA (PCNA) Antibodies

Full name:
anti-Proliferating Cell Nuclear Antigen Antibodies (PCNA)
On www.antibodies-online.com are 446 Proliferating Cell Nuclear Antigen (PCNA) Antibodies from 41 different suppliers available. Additionally we are shipping PCNA Kits (52) and PCNA Proteins (40) and many more products for this protein. A total of 558 PCNA products are currently listed.
Synonyms:
53/13, AO090003000846, cb16, CG9193, Dmel\\CG9193, DmPCNA, dPCNA, fb36g03, l(2)02448, l(2)56F, l(2)56Fa, l(2)s1534, Mus209, pcna, pcna-A, Pcna/cyclin, PCNA/mus209, PCNAR, wu:fa28e03, wu:fb36g03
list all antibodies Gene Name GeneID UniProt
PCNA 5111 P12004
Anti-Mouse PCNA PCNA 18538 P17918
Anti-Rat PCNA PCNA 25737 P04961

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Top referenced anti-PCNA Antibodies

  1. Human Polyclonal PCNA Primary Antibody for IF, IHC (p) - ABIN389344 : Wang, Zheng, Luo, Fan, Chen, Zhang, Hui: KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation. in Journal of cellular biochemistry 2009 (PubMed)
    Show all 7 references for ABIN389344

  2. Human Monoclonal PCNA Primary Antibody for WB - ABIN1882273 : Almendral, Huebsch, Blundell, Macdonald-Bravo, Bravo: Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins. in Proceedings of the National Academy of Sciences of the United States of America 1987 (PubMed)
    Show all 4 references for ABIN1882273

  3. Human Polyclonal PCNA Primary Antibody for IP, IHC - ABIN223074 : Lyzogubov, Tytarenko, Thotakura, Viswanathan, Bora, Bora: Inhibition of new vessel growth in mouse model of laser-induced choroidal neovascularization by adiponectin peptide II. in Cell biology international 2009 (PubMed)
    Show all 3 references for ABIN223074

  4. Human Polyclonal PCNA Primary Antibody for EIA, WB - ABIN358006 : Maga, Crespan, Wimmer, van Loon, Amoroso, Mondello, Belgiovine, Ferrari, Locatelli, Villani, Hübscher: Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 references for ABIN358006

  5. Human Polyclonal PCNA Primary Antibody for FACS, IF - ABIN389345 : Acharya, Yoon, Gali, Unk, Haracska, Johnson, Hurwitz, Prakash, Prakash: Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 references for ABIN389345

  6. Human Monoclonal PCNA Primary Antibody for IHC (fro), IF - ABIN1108598 : Bravo: Synthesis of the nuclear protein cyclin (PCNA) and its relationship with DNA replication. in Experimental cell research 1986 (PubMed)
    Show all 3 references for ABIN1108598

  7. Human Monoclonal PCNA Primary Antibody for FACS, IHC - ABIN1724760 : Takawa, Cho, Hayami, Toyokawa, Kogure, Yamane, Iwai, Maejima, Ueda, Masuda, Dohmae, Field, Tsunoda, Kobayashi, Akasu, Sugiyama, Ohnuma, Atomi, Ponder, Nakamura, Hamamoto: Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. in Cancer research 2012 (PubMed)
    Show all 2 references for ABIN1724760

  8. Chicken Polyclonal PCNA Primary Antibody for EIA, IHC (p) - ABIN401372 : Chuang, Ian, Koh, Ng, Xu, Li: Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. in Science (New York, N.Y.) 1997 (PubMed)

  9. Cow (Bovine) Polyclonal PCNA Primary Antibody for IHC, WB - ABIN2792157 : Senga, Sivaprasad, Zhu, Park, Arias, Walter, Dutta: PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against PCNA Interaction Partners

Fruit Fly (Drosophila melanogaster) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Results show that regulation of e2f1 (show E2F1 Antibodies) and PCNA by DREF (show ZBED1 Antibodies) in vivo is complex and the regulation mechanism may differ with the tissue and/or positions in the tissue.

  2. crystal of DmPCNA diffracted to 2.0 A resolution and belonged to space group H3, with unit-cell parameters a = b = 151.16, c = 38.28 A

  3. We observed that SUUR chromosomal localization changed along with PCNA pattern and these proteins largely co-localized during the late S-phase in salivary glands.

  4. E2F (show E2F2 Antibodies) regulation of PCNA is dispensable for viability, but is nonetheless important for normal Drosophila development.

  5. A Q123V mutation dramaticly enhances the abilities of Drosophila PCNA to stimulate calf thymus pol delta (show POLD1 Antibodies). Replacing the entire interdomain connector loop AA 119-133 with the corresponding residues from human PCNA results in additional enhancement.

Tomato (Solanum lycopersicum) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. tomato DDI2 gene is required for UV-induced DNA damage repair and plant tolerance to UV stress. [DDI2]

Human Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. The authors describe the structure of the disease-causing S228I variant, which reveals a large conformational change that dramatically transforms the binding pocket for PCNA client proteins.

  2. Studies show that acidic residue methyltransferase 1 (show DNMT1 Antibodies) (Armt1) has a vital role in regulation of the DNA damage response likely through its ability to O-methylate glutamyl residues of the DNA repair factor proliferating cell nuclear antigen (PCNA).

  3. Hydrophobic pocket of PCNA is the key domain mediating ALKBH2 (show ALKBH2 Antibodies)/PCNA interaction. PCNA association with ALKBH2 (show ALKBH2 Antibodies) increases significantly during DNA replication, suggesting that ALKBH2 (show ALKBH2 Antibodies) forms a cell-cycle dependent complex with PCNA.

  4. Report PCNA expression in giant cell tumor of bones.

  5. adenine glycosylase activity, mismatch recognition properties and interaction with protein partners of MUTYH (show MUTYH Antibodies) and 5 MAP variants were examined; P502L and R520Q had reduced affinity for PCNA; only Q324H was found to have reduced affinity for Hus1 (show HUS1 Antibodies)

  6. p15PAF acts as a flexible drag that regulates PCNA sliding along the DNA and facilitates the switch from replicative to translesion synthesis polymerase binding.

  7. 14-3-3zeta (show YWHAZ Antibodies) reduces DNA damage by interacting with and stabilizing proliferating cell nuclear antigen

  8. data indicated that IncRNA-PCNA-AS1 may participate in the gastric cancer carcinogenesis and development and may serve as a new biomarker for patients with gastric cancer

  9. Bub1 (show BUB1 Antibodies) in complex with LANA recruits PCNA to regulate Kaposi's sarcoma-associated herpesvirus latent replication and DNA translesion synthesis.

  10. Results revealed that mutation of lysine K164 in PCNA disrupts mono-ubiquitination of the multiple units within a homo-trimer complex as well as a DNA damage tolerance pathway.

Mouse (Murine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Data suggest Usp1 (ubiquitin specific peptidase 1 (show USP1 Antibodies)) down-regulation by autocleavage is critical for Usp1 (show USP1 Antibodies) to exert role in DNA interstrand crosslink repair; Usp1 (show USP1 Antibodies) role is de-ubiquitination of Pcna and Fancd2 (Fanconi anemia complementation group D2 (show FANCD2 Antibodies)).

  2. The aberrant DNA replication mediated by the PCNA-DNA pol-beta (show POLB Antibodies) complex induces p53 (show TP53 Antibodies)-dependent neuronal cell death

  3. Demonstrate that miR (show MLXIP Antibodies)-376a regulates primordial follicle assembly by modulating the expression of Pcna.

  4. while interaction with PCNA was important for targeting p21 (show D4S234E Antibodies) to the CRL4Cdt2 ligase re-localized to MVM replication centers

  5. Styrax japonica glycoprotein increased diethylnitrosamine-induced PCNA activity.

  6. This study identifies a critical role for PCNA in adipose tissue development, and for the first time identifies a role of the core DNA replication machinery at the interface between proliferation and differentiation.

  7. Seaweed pigment glycoprotein reduced the expression of PCNA and Bcl2 (show BCL2 Antibodies), which reduced proliferation of hepatocarcinoma cells.

  8. These results suggest that the ncRNA is divergently transcribed from the bidirectional promoter, positively regulating the neighboring protein-coding Pcna gene transcription, and this regulatory function is somehow disrupted in cancer cells.

  9. these data support the existence of PCNA ubiquitination-dependent and -independent activation pathways of Poleta during somatic hypermutation and DNA damage tolerance.

  10. Taken together these results indicate that PCNA-ubiquitination is required for maximal translesion DNA synthesis.

Zebrafish Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Antibodies), wee1 (show WEE1 Antibodies), p21 (show CDKN1A Antibodies), PCNA and cdk2 (show CDK2 Antibodies), but only weakly influences cyclin B1 (show CCNB1 Antibodies), cyclin B2 (show CCNB2 Antibodies) and cyclin E1 (show CCNE1 Antibodies) expression.

Pig (Porcine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. There is a link between the intestinal detoxification system (CYP1A) & cell renewal system (PCNA). These two processes are inversely correlated in beta-naphthoflavone- exposed fish

Xenopus laevis Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. residue in PCNA that is essential to support destruction of all CRL4(Cdt2) substrates

  2. CRL4Cdt2 ubiquitin ligase directly associates with pcna through its C-terminal domain.

  3. PCNA monoubiquitylation serves as a molecular gas pedal that controls the speed of replisome movement during S phase.

  4. Immunodepletion of Swift PAX-interacting protein 1 (show PAXIP1 Antibodies) from Xenopus extracts prevented efficient PCNA ubiquitination

  5. PCNA docking activates the pre-formed Cdt1 (show CDT1 Antibodies)-Cul4(DDB1 (show DDB1 Antibodies)) ligase complex. Thus, PCNA functions as a platform for Cdt1 (show CDT1 Antibodies) destruction, ensuring efficient and temporally restricted inactivation of a key cell-cycle regulator (show CDKN2A Antibodies).

PCNA Antigen Profile

Antigen Summary

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Alternative names and synonyms associated with PCNA

  • mutagen-sensitive 209 (mus209) antibody
  • proliferating cell nuclear antigen (pcna) antibody
  • proliferating cell nuclear antigen (pcnA) antibody
  • proliferating cell nuclear antigen (ANI_1_512014) antibody
  • proliferating cell nuclear antigen (AOR_1_1500154) antibody
  • proliferating cell nuclear antigen (PCNA) antibody
  • proliferating cell nuclear antigen (Pcna) antibody
  • Proliferating cell nuclear antigen-like (MGC53867) antibody
  • proliferating cell nuclear antigen-like (LOC100339381) antibody
  • proliferating cell nuclear antigen1 (pcna1) antibody
  • 53/13 antibody
  • AO090003000846 antibody
  • cb16 antibody
  • CG9193 antibody
  • Dmel\\CG9193 antibody
  • DmPCNA antibody
  • dPCNA antibody
  • fb36g03 antibody
  • l(2)02448 antibody
  • l(2)56F antibody
  • l(2)56Fa antibody
  • l(2)s1534 antibody
  • Mus209 antibody
  • pcna antibody
  • pcna-A antibody
  • Pcna/cyclin antibody
  • PCNA/mus209 antibody
  • PCNAR antibody
  • wu:fa28e03 antibody
  • wu:fb36g03 antibody

Protein level used designations for PCNA

CG9193-PA , CG9193-PB , Proliferating-cell-nuclear-antigen , mus209-PA , mus209-PB , proliferating cell nuclear antigen , proliferating-cell nuclear antigen , DNA polymerase delta auxiliary protein , cyclin , etID36690.10 , fa28e03 , proliferating cell nuclear antigen subtype1 , proliferating cell nuclear antigen subtype2 , proliferating cell nuclear antigen subtype3 , CL1137_1 , CL1137_1(454) , CL1137_1_ov , proliferative cell nuclear antigen

GENE ID SPECIES
37290 Drosophila melanogaster
544248 Solanum lycopersicum
857128 Guillardia theta
2761382 Methanococcus maripaludis S2
4978203 Aspergillus niger CBS 513.88
5788447 Bigelowiella natans
5991960 Aspergillus oryzae RIB40
10447350 Cryptomonas paramecium
5111 Homo sapiens
18538 Mus musculus
25737 Rattus norvegicus
30678 Danio rerio
477166 Canis lupus familiaris
515499 Bos taurus
373984 Gallus gallus
692192 Sus scrofa
100713865 Cavia porcellus
443155 Ovis aries
692356 Bombyx mori
394328 Xenopus laevis
100689335 Cricetulus griseus
398425 Xenopus laevis
100339381 Oryctolagus cuniculus
542425 Zea mays
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