Browse our anti-PCNA (PCNA) Antibodies

Full name:
anti-Proliferating Cell Nuclear Antigen Antibodies (PCNA)
On are 717 Proliferating Cell Nuclear Antigen (PCNA) Antibodies from 42 different suppliers available. Additionally we are shipping PCNA Kits (53) and PCNA Proteins (38) and many more products for this protein. A total of 825 PCNA products are currently listed.
53/13, AO090003000846, cb16, CG9193, Dmel\\CG9193, DmPCNA, dPCNA, fb36g03, l(2)02448, l(2)56F, l(2)56Fa, l(2)s1534, Mus209, pcna, pcna-A, Pcna/cyclin, PCNA/mus209, PCNAR, wu:fa28e03, wu:fb36g03
list all antibodies Gene Name GeneID UniProt
PCNA 5111 P12004
Anti-Mouse PCNA PCNA 18538 P17918
Anti-Rat PCNA PCNA 25737 P04961

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All available anti-PCNA Antibodies

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Top referenced anti-PCNA Antibodies

  1. Chicken Monoclonal PCNA Primary Antibody for ChIP, ELISA - ABIN152935 : Waseem, Lane: Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form. in Journal of cell science 1990 (PubMed)
    Show all 22 references for 152935

  2. Human Polyclonal PCNA Primary Antibody for IF, IHC (p) - ABIN389344 : Wang, Zheng, Luo, Fan, Chen, Zhang, Hui: KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation. in Journal of cellular biochemistry 2009 (PubMed)
    Show all 7 references for 389344

  3. Human Monoclonal PCNA Primary Antibody for IF (p), IHC (p) - ABIN723006 : Hao, Zhang, Cheng, Li, Sun, Zhang, Guo, Li: Imidapril inhibits right ventricular remodeling induced by low ambient temperature in broiler chickens. in Poultry science 2013 (PubMed)
    Show all 4 references for 723006

  4. Human Polyclonal PCNA Primary Antibody for IF (p), IHC (p) - ABIN672756 : Song, Yan, An, Hao, Guo, Zhang, Li, Li, Sun: Potential contribution of SOCC to cerebral vasospasm after experimental subarachnoid hemorrhage in rats. in Brain research 2013 (PubMed)
    Show all 4 references for 672756

  5. Human Polyclonal PCNA Primary Antibody for FACS, IF - ABIN389345 : Maga, Crespan, Wimmer, van Loon, Amoroso, Mondello, Belgiovine, Ferrari, Locatelli, Villani, Hübscher: Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 references for 389345

  6. Human Monoclonal PCNA Primary Antibody for IHC (fro), IF - ABIN1108598 : Bravo: Synthesis of the nuclear protein cyclin (PCNA) and its relationship with DNA replication. in Experimental cell research 1986 (PubMed)
    Show all 3 references for 1108598

  7. Human Polyclonal PCNA Primary Antibody for EIA, WB - ABIN358006 : Acharya, Yoon, Gali, Unk, Haracska, Johnson, Hurwitz, Prakash, Prakash: Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 3 references for 358006

  8. Human Polyclonal PCNA Primary Antibody for IP, IHC - ABIN223074 : Lyzogubov, Tytarenko, Thotakura, Viswanathan, Bora, Bora: Inhibition of new vessel growth in mouse model of laser-induced choroidal neovascularization by adiponectin peptide II. in Cell biology international 2009 (PubMed)
    Show all 3 references for 223074

  9. Cow (Bovine) Polyclonal PCNA Primary Antibody for IHC, WB - ABIN2792157 : Senga, Sivaprasad, Zhu, Park, Arias, Walter, Dutta: PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for 2792157

  10. Human Polyclonal PCNA Primary Antibody for IF (p), IHC (p) - ABIN676583 : Liang, Peng, Li, Yang, Xie, Li, Du, Zhang: Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin. in Oncotarget 2015 (PubMed)
    Show all 2 references for 676583

More Antibodies against PCNA Interaction Partners

Fruit Fly (Drosophila melanogaster) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Results show that regulation of e2f1 (show E2F1 Antibodies) and PCNA by DREF (show ZBED1 Antibodies) in vivo is complex and the regulation mechanism may differ with the tissue and/or positions in the tissue.

  2. crystal of DmPCNA diffracted to 2.0 A resolution and belonged to space group H3, with unit-cell parameters a = b = 151.16, c = 38.28 A

  3. We observed that SUUR chromosomal localization changed along with PCNA pattern and these proteins largely co-localized during the late S-phase in salivary glands.

  4. E2F (show E2F2 Antibodies) regulation of PCNA is dispensable for viability, but is nonetheless important for normal Drosophila development.

  5. A Q123V mutation dramaticly enhances the abilities of Drosophila PCNA to stimulate calf thymus pol delta (show POLD1 Antibodies). Replacing the entire interdomain connector loop AA 119-133 with the corresponding residues from human PCNA results in additional enhancement.

Tomato (Solanum lycopersicum) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. tomato DDI2 gene is required for UV-induced DNA damage repair and plant tolerance to UV stress. [DDI2]

Human Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Multiple studies provide evidence that PCNA lies at the center of the faithful duplication of eukaryotic genomes and therefore genome integrity. [review]

  2. Human CTF18-RFC clamp-loader complexed with non-synthesising POLE efficiently loads the PCNA sliding clamp.

  3. Results suggest that the UNG2 N-terminus may serve as a flexible scaffold to tether PCNA and RPA at the replication fork, and that post-translational modifications on the UNG2 N-terminus disrupt formation of the PCNA-UNG2-RPA protein complex.

  4. ECRG2 (show SPINK7 Antibodies) in combination with cisplatin (DDP (show TIMM8A Antibodies)) can inhibit viability and induce apoptosis in esophageal cancer DDP (show TIMM8A Antibodies)-resistant cells, possibly via upregulation of p53 (show TP53 Antibodies) expression and downregulation of PCNA expression.

  5. Reduced affinity of PCNA(S228I) for specific clients causes subtle cellular defects in undamaged cells which likely contribute to the etiology of PCNA-associated DNA repair disorder (PARD). Analysis of the binding between PCNA and PCNA-interacting proteins (PIPs (show GPRASP1 Antibodies)) shows that the S228I change dramatically impairs the majority of these interactions, including that of Cdt1 (show CDT1 Antibodies), DNMT1 (show DNMT1 Antibodies), PolD3(p66 (show POLD3 Antibodies)) and PolD4(p12 (show POLD4 Antibodies)).

  6. Data suggest that, during human DNA replication, restricting PCNA (proliferating cell nuclear antigen) to the vicinity of its DNA target site is important; PCNA can be maintained at or near primer/template junctions during DNA synthesis by RPA (show RPA1 Antibodies) (replication protein A (show GPR153 Antibodies)) or SSB (single-stranded DNA-binding protein (show RPA1 Antibodies)); here, the SSB used was from Escherichia coli.

  7. Studies demonstrated that POLH (show POLH Antibodies) interaction with PCNA plays an indispensable role in the recruitment of pol-eta to UV-induced cyclobutane pyrimidine dimers site to carry out translesion synthesis (TLS (show FUS Antibodies)), and the dissociation of pol-eta from PCNA after TLS (show FUS Antibodies) is essential for maintaining high fidelity DNA replication.

  8. PCNA is a substrate of the HSV-1 deubiquitinase UL36USP, which has previously been shown to be involved mainly in virus uptake and maturation

  9. Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling

  10. PCNA plays a critical role in preventing CAG repeat (show CELF3 Antibodies) expansions by modulating the structures of dynamic DNA via cooperation with base excision repair enzymes.

Mouse (Murine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (show TRAF1 Antibodies)/NF-kappaB (show NFKB1 Antibodies)-regulated apoptosis and the p53 (show TP53 Antibodies)/PCNA- and ATM (show ATM Antibodies)/ATR (show ATR Antibodies)-Chk1 (show CHEK1 Antibodies)/2-controlled DNA-damage response pathways.

  2. REV1 promote PCNA monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18 (show RAD18 Antibodies).

  3. PCNA was mainly localized in decidual-stromal cells.

  4. Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA and up-regulation of ICAM-1 (show ICAM1 Antibodies) in tumor tissue of tumor-bearing mice, thereby achieving its anti-tumor effect.

  5. Data suggest Usp1 (ubiquitin specific peptidase 1 (show USP1 Antibodies)) down-regulation by autocleavage is critical for Usp1 (show USP1 Antibodies) to exert role in DNA interstrand crosslink repair; Usp1 (show USP1 Antibodies) role is de-ubiquitination of Pcna and Fancd2 (Fanconi anemia complementation group D2 (show FANCD2 Antibodies)).

  6. The aberrant DNA replication mediated by the PCNA-DNA pol-beta (show POLB Antibodies) complex induces p53 (show TP53 Antibodies)-dependent neuronal cell death

  7. Demonstrate that miR (show MLXIP Antibodies)-376a regulates primordial follicle assembly by modulating the expression of Pcna.

  8. while interaction with PCNA was important for targeting p21 (show D4S234E Antibodies) to the CRL4Cdt2 ligase re-localized to MVM replication centers

  9. Styrax japonica glycoprotein increased diethylnitrosamine-induced PCNA activity.

  10. This study identifies a critical role for PCNA in adipose tissue development, and for the first time identifies a role of the core DNA replication machinery at the interface between proliferation and differentiation.

Zebrafish Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. The expression of telomerase activity and TERT (show TERT Antibodies) in retina implies that telomerase has functions other than the elongation of telomere. These findings could provide new insights on telomerase function in the nervous system.

  2. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Antibodies), wee1 (show WEE1 Antibodies), p21 (show CDKN1A Antibodies), PCNA and cdk2 (show CDK2 Antibodies), but only weakly influences cyclin B1 (show CCNB1 Antibodies), cyclin B2 (show CCNB2 Antibodies) and cyclin E1 (show CCNE1 Antibodies) expression.

Pig (Porcine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. There is a link between the intestinal detoxification system (CYP1A) & cell renewal system (PCNA). These two processes are inversely correlated in beta-naphthoflavone- exposed fish

Xenopus laevis Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. residue in PCNA that is essential to support destruction of all CRL4(Cdt2) substrates

  2. CRL4Cdt2 ubiquitin ligase directly associates with pcna through its C-terminal domain.

  3. PCNA monoubiquitylation serves as a molecular gas pedal that controls the speed of replisome movement during S phase.

  4. Immunodepletion of Swift PAX-interacting protein 1 (show PAXIP1 Antibodies) from Xenopus extracts prevented efficient PCNA ubiquitination

  5. PCNA docking activates the pre-formed Cdt1 (show CDT1 Antibodies)-Cul4(DDB1 (show DDB1 Antibodies)) ligase complex. Thus, PCNA functions as a platform for Cdt1 (show CDT1 Antibodies) destruction, ensuring efficient and temporally restricted inactivation of a key cell-cycle regulator (show CDKN2A Antibodies).

PCNA Antigen Profile

Antigen Summary

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Alternative names and synonyms associated with PCNA

  • mutagen-sensitive 209 (mus209) antibody
  • proliferating cell nuclear antigen (pcna) antibody
  • proliferating cell nuclear antigen (pcnA) antibody
  • proliferating cell nuclear antigen (ANI_1_512014) antibody
  • proliferating cell nuclear antigen (AOR_1_1500154) antibody
  • proliferating cell nuclear antigen (PCNA) antibody
  • proliferating cell nuclear antigen (Pcna) antibody
  • Proliferating cell nuclear antigen-like (MGC53867) antibody
  • proliferating cell nuclear antigen-like (LOC100339381) antibody
  • proliferating cell nuclear antigen1 (pcna1) antibody
  • 53/13 antibody
  • AO090003000846 antibody
  • cb16 antibody
  • CG9193 antibody
  • Dmel\\CG9193 antibody
  • DmPCNA antibody
  • dPCNA antibody
  • fb36g03 antibody
  • l(2)02448 antibody
  • l(2)56F antibody
  • l(2)56Fa antibody
  • l(2)s1534 antibody
  • Mus209 antibody
  • pcna antibody
  • pcna-A antibody
  • Pcna/cyclin antibody
  • PCNA/mus209 antibody
  • PCNAR antibody
  • wu:fa28e03 antibody
  • wu:fb36g03 antibody

Protein level used designations for PCNA

CG9193-PA , CG9193-PB , Proliferating-cell-nuclear-antigen , mus209-PA , mus209-PB , proliferating cell nuclear antigen , proliferating-cell nuclear antigen , DNA polymerase delta auxiliary protein , cyclin , etID36690.10 , fa28e03 , proliferating cell nuclear antigen subtype1 , proliferating cell nuclear antigen subtype2 , proliferating cell nuclear antigen subtype3 , CL1137_1 , CL1137_1(454) , CL1137_1_ov , proliferative cell nuclear antigen

37290 Drosophila melanogaster
544248 Solanum lycopersicum
857128 Guillardia theta
2761382 Methanococcus maripaludis S2
4978203 Aspergillus niger CBS 513.88
5788447 Bigelowiella natans
5991960 Aspergillus oryzae RIB40
10447350 Cryptomonas paramecium
5111 Homo sapiens
18538 Mus musculus
25737 Rattus norvegicus
30678 Danio rerio
477166 Canis lupus familiaris
515499 Bos taurus
373984 Gallus gallus
692192 Sus scrofa
100713865 Cavia porcellus
443155 Ovis aries
692356 Bombyx mori
394328 Xenopus laevis
100689335 Cricetulus griseus
398425 Xenopus laevis
100339381 Oryctolagus cuniculus
542425 Zea mays
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