PCNA antibody (AA 1-261)

Catalog No. ABIN562136

There is 1 publication for this product available. The Mouse Monoclonal anti-PCNA antibody is suitable to detect PCNA in samples from Human. It has been validated for WB and ELISA.

Quick Overview for PCNA antibody (AA 1-261) (ABIN562136)

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PCNA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: S1

Product Details anti-PCNA Antibody

Binding Specificity: AA 1-261

Purpose: Mouse monoclonal antibody raised against a full length recombinant PCNA.

Sequence: MFEARLVQGS ILKKVLEALK DLINEACWDI SSSGVNLQSM DSSHVSLVQL TLRSEGFDTY RCDRNLAMGV NLTSMSKILK CAGNEDIITL RAEDNADTLA LVFEAPNQEK VSDYEMKLMD LDVEQLGIPE QEYSCVVKMP SGEFARICRD LSHIGDAVVI SCAKDGVKFS ASGELGNGNI KLSQTSNVDK EEEAVTIEMN EPVQLTFALR YLNFFTKATP LSSTVTLSMS ADVPLVVEYK IADMGHLKYY LAPKIEDEEG S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PCNA (AAH00491, 1 a.a. ~ 261 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PCNA antibody (ABIN562136)

Hsieh, Fan, Chang, Chen, Shen, Teng, Yeh, Li: "DNA topoisomerase III alpha regulates p53-mediated tumor suppression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 6, pp. 1489-501, (2014) (PubMed).

Target Details for PCNA

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Alternative Name: PCNA

Background: Full Gene Name: proliferating cell nuclear antigen
Synonyms: MGC8367

Gene ID: 5111

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy