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Browse our anti-TERT (TERT) Antibodies

Full name:
anti-Telomerase Reverse Transcriptase Antibodies (TERT)
On are 238 Telomerase Reverse Transcriptase (TERT) Antibodies from 24 different suppliers available. Additionally we are shipping TERT Kits (59) and TERT Proteins (10) and many more products for this protein. A total of 323 TERT products are currently listed.
ATTERT, chTERT, CMM9, DKCA2, DKCB4, EST2, F5E19.190, F5E19_190, hEST2, hTRT, PFBMFT1, TCS1, telomerase reverse transcriptase, tert, TP2, TR, TRT

Most Popular Reactivities for anti-TERT (TERT) Antibodies

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anti-Human TERT Antibodies:

anti-Mouse (Murine) TERT Antibodies:

anti-Rat (Rattus) TERT Antibodies:

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Top referenced anti-TERT Antibodies

  1. Human Polyclonal TERT Primary Antibody for ELISA, WB - ABIN1532760 : Nakamura, Morin, Chapman, Weinrich, Andrews, Lingner, Harley, Cech: Telomerase catalytic subunit homologs from fission yeast and human. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 3 references for ABIN1532760

  2. Human Polyclonal TERT Primary Antibody for IF, ELISA - ABIN1532759 : Meyerson, Counter, Eaton, Ellisen, Steiner, Caddle, Ziaugra, Beijersbergen, Davidoff, Liu, Bacchetti, Haber, Weinberg: hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. in Cell 1997 (PubMed)
    Show all 3 references for ABIN1532759

  3. Human Polyclonal TERT Primary Antibody for ELISA, WB - ABIN1531730 : Hisatomi, Ohyashiki, Ohyashiki, Nagao, Kanamaru, Hirata, Hibi, Tsukada: Expression profile of a gamma-deletion variant of the human telomerase reverse transcriptase gene. in Neoplasia (New York, N.Y.) 2003 (PubMed)
    Show all 3 references for ABIN1531730

  4. Human Polyclonal TERT Primary Antibody for FACS, IF - ABIN388165 : Sekaric, Cherry, Androphy: Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT. in Journal of virology 2007 (PubMed)
    Show all 3 references for ABIN388165

  5. Human Polyclonal TERT Primary Antibody for IF, ELISA - ABIN1531729 : Wick, Zubov, Hagen: Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). in Gene 1999 (PubMed)
    Show all 3 references for ABIN1531729

  6. Human Polyclonal TERT Primary Antibody for FACS, IF - ABIN388164 : Okawa, Michaylira, Kalabis, Stairs, Nakagawa, Andl, Johnstone, Klein-Szanto, El-Deiry, Cukierman, Herlyn, Rustgi et al.: The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and ... in Genes & development 2007 (PubMed)
    Show all 2 references for ABIN388164

  7. Human Polyclonal TERT Primary Antibody for DB, IF - ABIN390002 : Radan, Hughes, Teichroeb, Vieira Zamora, Jewer, Postovit, Betts: Microenvironmental regulation of telomerase isoforms in human embryonic stem cells. in Stem cells and development 2014 (PubMed)
    Show all 2 references for ABIN390002

  8. Human Polyclonal TERT Primary Antibody for EIA - ABIN358545 : Jakob, Schroeder, Lukosz, Büchner, Spyridopoulos, Altschmied, Haendeler: Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN358545

More Antibodies against TERT Interaction Partners

Caenorhabditis elegans (C. elegans) Telomerase Reverse Transcriptase (TERT) interaction partners

  1. trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase

Zebrafish Telomerase Reverse Transcriptase (TERT) interaction partners

  1. The expression of telomerase activity and TERT in retina implies that telomerase has functions other than the elongation of telomere. These findings could provide new insights on telomerase function in the nervous system.

  2. methylation status of the genes of telomerase reverse transcriptase (tert) and telomerase RNA (terc) was determined in brain tissues; study found that, regardless of the age of fish, the regulatory region of the tert gene was completely methylated, whereas the coding region remained unmethylated

  3. Telomerase-deficient zebrafish show p53 (show TP53 Antibodies)-dependent premature aging and reduced lifespan in the first generation.

  4. These results suggest that TERT non-canonically functions in hematopoietic cell differentiation and survival in vertebrates, independently of its role in telomere homeostasis.

Candida albicans Telomerase Reverse Transcriptase (TERT) interaction partners

  1. Telomerase regulatory subunit Est3 in Candida species physically interacts with the TEN domain of TERT and telomeric DNA

Medaka Telomerase Reverse Transcriptase (TERT) interaction partners

  1. Tert was cloned from testis. It is expresed in embryo and adult, mostly in gonad and brain. 2 splice variants and an antisense transcript were identified.

  2. The Japanese medaka is a new vertebrate model for studying tert biology.

Human Telomerase Reverse Transcriptase (TERT) interaction partners

  1. The results showed that a repressor complex composed of NFX1 (show NFX1 Antibodies)-91, mSin3A and histone deacetylase 1 (show HDAC1 Antibodies) was involved in the PKC-delta (show PKCd Antibodies)-induced repression of the hTERT promoter, which resulted in the repression of hTERT transcription.

  2. Results indicate a noncanonical function for telomerase catalytic subunit (hTERT) in promoting tumorigenesis.

  3. Gene alterations in TERT promoter, TP53 (show TP53 Antibodies), CTNNB1 (show CTNNB1 Antibodies), and hepatitis B virus integration were closely associated with hepatocellular carcinoma development, and mutations in TERT promoter are related to poor prognosis

  4. A high percentage of glioma cell lines, as well as two meningioma cell lines, harbors TERT mutations.

  5. Tert knockdown disrupts telomere homeostasis and could inhibit growth of fibroblasts in scar tissues.

  6. A significant TERT hypermethylation in breast cancer cells was observed in four CpG islands as a sum, in comparison to methylation of the normal breast tissue.

  7. Differences in patterns of methylation of the hTERT core promoter [region 1 (nt -208 to -1) and region 2 (nt +1 to +104) relative to first ATG] are related to the HPV species present.

  8. Oncogenic TERT promoter mutations are present in a fraction of ALMs. No relevant associations were found between TERT mutation status and clinical/molecular features nor survival.

  9. TERT promoter mutations and long telomere length is associated with radiotherapy resistance in gliomas.

  10. Studies showed that TERT mutations occur early during cellular transformation, and activate the TERT promoter by recruiting transcription factors that do not normally regulate TERT gene expression. [review]

Mouse (Murine) Telomerase Reverse Transcriptase (TERT) interaction partners

  1. This study reports the characterisation of two novel mouse TERT splice variants, Ins (show INS Antibodies)-i1[1-102] (Insi1 for short) and Del-e12 (show ELSPBP1 Antibodies)[1-40] (Dele12 for short) that have not been previously described. Insi1 represents an in-frame insertion of nucleotides 1-102 from intron 1, encoding a 34 amino acid insertion at amino acid 73.

  2. TERT may promote gastric cancer metastasis through the TERT-miR (show MLXIP Antibodies)-29a-ITGB1 (show ITGB1 Antibodies) regulatory pathway.

  3. TERT switches macrophages towards M1 phenotype by regulating NF-kappaB (show NFKB1 Antibodies) signaling, but has limited effect on M2 macrophages polarization in vitro.

  4. miR (show MLXIP Antibodies)-195 overexpressed in old mesenchymal stem cells (OMSCs) induces stem cell senescence deteriorating their regenerative ability by directly deactivating telomerase reverse transcriptase (Tert), and abrogation of miR (show MLXIP Antibodies)-195 can reverse stem cell aging.

  5. findings identified a key role for TERT in fibroblast proliferation and survival essential for pulmonary fibrosis

  6. miR (show MLXIP Antibodies)-512-5p suppresses tumor growth by targeting TERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.

  7. data suggest that S1P (show S1PR1 Antibodies) binding to hTERT allosterically mimicks phosphorylation, promoting telomerase stability and hence telomere maintenance, cell proliferation, and tumor growth.

  8. Telomerase may direct Pol I transcription in oncogenic and regenerative hyperproliferation.

  9. Tert expression confers cardioprotection in the adult mouse heart after acute myocardial infarction.

  10. TERT is a regulator of MYC (show MYC Antibodies) stability in cancer. Reactivation of TERT, a direct transcriptional MYC (show MYC Antibodies) target in tumors, provides a feed-forward mechanism to potentiate MYC (show MYC Antibodies)-dependent oncogenesis.

Cow (Bovine) Telomerase Reverse Transcriptase (TERT) interaction partners

Arabidopsis thaliana Telomerase Reverse Transcriptase (TERT) interaction partners

  1. Telomere shortening is more rapid in fas (show FASN Antibodies) tert double mutants than in fas1 (show FAS Antibodies), fas2 or tert single mutant plants.

  2. Silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment.

  3. study reports the physical interaction of an Arabidopsis POT1 (show POT1 Antibodies) protein, POT1A (show POT1 Antibodies) (At5g05210), with an N-terminal peptide of the catalytic subunit of the telomerase TERT encoded by a 5' mRNA splicing variant

  4. AtTERT, the telomerase catalytic subunit, accumulates in the plant nucleolus, and AtNAP57 (show DKC1 Antibodies) associates with active telomerase RNP (show RNPC3 Antibodies) particles in an RNA-dependent manner.

  5. Attert (-/-) mutant plants were propagated from seeds coming either from the lower-most or the upper-most siliques (L- and U-plants) and the length of their telomeres were followed over several generations.

TERT Antigen Profile

Antigen Summary

Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified\; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.

Alternative names and synonyms associated with TERT

  • Telomerase Reverse Transcriptase (trt-1) antibody
  • telomerase reverse transcriptase (Tert) antibody
  • telomerase reverse transcriptase (tert) antibody
  • telomerase reverse transcriptase (TRT1) antibody
  • telomerase reverse transcriptase (CMU_003490) antibody
  • telomerase reverse transcriptase (VDBG_04487) antibody
  • Telomerase catalytic subunit (GL50803_16225) antibody
  • telomerase reverse transcriptase (TERT) antibody
  • ATTERT antibody
  • chTERT antibody
  • CMM9 antibody
  • DKCA2 antibody
  • DKCB4 antibody
  • EST2 antibody
  • F5E19.190 antibody
  • F5E19_190 antibody
  • hEST2 antibody
  • hTRT antibody
  • PFBMFT1 antibody
  • TCS1 antibody
  • telomerase reverse transcriptase antibody
  • tert antibody
  • TP2 antibody
  • TR antibody
  • TRT antibody

Protein level used designations for TERT

Telomerase Reverse Transcriptase family member (trt-1) , telomerase reverse transcriptase , hypothetical protein , Telomerase catalytic subunit , telomerase catalytic subunit , telomerase-associated protein 2 , telomerase reverse transcriptase beta

172688 Caenorhabditis elegans
658162 Tribolium castaneum
796551 Danio rerio
3640729 Candida albicans SC5314
3640809 Candida albicans SC5314
6997965 Cryptosporidium muris RN66
9530095 Verticillium alfalfae VaMs.102
100049443 Oryzias latipes
5702495 Giardia lamblia ATCC 50803
7015 Homo sapiens
21752 Mus musculus
301965 Rattus norvegicus
518884 Bos taurus
403412 Canis lupus familiaris
492280 Sus scrofa
420972 Gallus gallus
100732437 Cavia porcellus
831548 Arabidopsis thaliana
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