Browse our Dynamin 1 Proteins (DNM1)

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Dynamin 1 Proteins (DNM1)
On are 5 Dynamin 1 (DNM1) Proteins from 4 different suppliers available. Additionally we are shipping Dynamin 1 Antibodies (146) and Dynamin 1 Kits (42) and many more products for this protein. A total of 197 Dynamin 1 products are currently listed.
AI838169, Dnm, dnm1, Ftfl, mKIAA4093, si:dkey-246l19.2
list all proteins Gene Name GeneID UniProt
DNM1 1759 Q05193
DNM1 13429 P39053
Rat DNM1 DNM1 140694 P21575

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Dynamin 1 Proteins (DNM1) by Origin

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More Proteins for Dynamin 1 Interaction Partners

Horse (Equine) Dynamin 1 (DNM1) interaction partners

  1. Equine herpesvirus type 1 pUL56-induced MHC-I endocytosis required dynamin and tyrosine kinase but was independent of clathrin and caveolin-1, the main constituents of the clathrin- and raft/caveola-mediated endocytosis pathways, respectively.

Human Dynamin 1 (DNM1) interaction partners

  1. Study delineates the phenotypic spectrum of DNM1 encephalopathy, an emerging disease of synaptic vesicle fission characterized by severe to profound developmental delay, infantile-onset epilepsy beginning with infantile spasms, and movement disorder. The genetic landscape of DNM1 encephalopathy is notable for the recurrent c.709C>T (p.Arg237Trp) variant and localization of mutations to specific domains of the protein.

  2. CLCb/Dyn1 (show DNM1L Proteins)-dependent adaptive clathrin-mediated endocytosis selectively altered EGF receptor (show EGFR Proteins) trafficking.

  3. interation of DG with laminin and dynamin is involved in the regulation of AQP4 (show AQP4 Proteins) internalization

  4. Down-regulation of Dyn1 (show DNM1L Proteins) activity enhances extracellular Nme1 (show NME1 Proteins) in human colon tumor cell lines.

  5. Hypoxic down-regulation of constitutive endocytosis is HIF-independent, and involves caveolin-1 (show CAV1 Proteins)-mediated inhibition of dynamin-dependent, membrane raft endocytosis.

  6. study reports 2 patients with early onset epileptic encephalopathy possessing de novo DNM1 mutations; detected the novel mutation c.127G>A (p.Gly43Ser) in a patient with Lennox-Gastaut syndrome, and a recurrent mutation c.709C>T (p.Arg237Trp) in a patient with West syndrome

  7. The rare variants in DNM1 were significantly associated with smoking status.

  8. Data indicate that stimulation of the dynamin GTPase activity by SH3 domains is determined by its middle domain.

  9. molecular simulations corroborate the bimodal character of dynamin action and indicate radial and axial forces as dominant, although not independent, drivers of hemi-fission and fission membrane- transformations, respectively

  10. Data indicate the dynamics of a dynamin 1-catalysed GTP (show AK3 Proteins) hydrolysis and tube-severing reaction in real time using fluorescence microscopy.

Mouse (Murine) Dynamin 1 (DNM1) interaction partners

  1. Dynamin may facilitate Fas (show FAS Proteins)-mediated apoptotic death in the brain, and Hsp70 (show HSP70 Proteins) may protect by preventing this trafficking.

  2. These results suggested that dynamin 1 was susceptible to the aging process, and that a reduction in dynamin 1 may result in hippocampaldependent memory deficits by disrupting endocytosis and the release of neurotransmitters.

  3. Tissue-specific dynamin-1 deletion at the calyx of Held decreases short-term depression through a mechanism distinct from vesicle resupply.

  4. findings support a role for HTT (show HTT Proteins) on dynamin 1 function and ER homoeostasis. Proteolysis-induced alteration of this function may be relevant to disease.

  5. the identification of the oligomerization cycle of dynamin is an attractive potential therapeutic target to treat chronic kidney diseases .

  6. In the developing neurons, there is a dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.

  7. Using an inducible knockout mouse model to generate dynamin 1- and 2-deficient primary osteoclast precursors and myoblasts, it was shown that fusion of both cell types requires dynamin.

  8. Dynamin 1 is required for memory formation.

  9. As low-level expression of the dynamin 3 (show DNM3 Proteins) gene in these cells could not be excluded, we have now engineered dynamin 1, 2 and 3 triple KO (TKO (show MRPS12 Proteins)) fibroblasts.

  10. Results further implicate dynamin-1 in vesicular protein transport processes relevant to synaptic and post-Golgi pathways and indicate a possible role in photoreceptor stability

Dynamin 1 (DNM1) Protein Profile

Protein Summary

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with Dynamin 1 (DNM1)

  • dynamin-1 (BACOIKO008_37)
  • dynamin-1 (PTRG_07818)
  • dynamin-1 (PTRG_08097)
  • dynamin 1 (dnm1)
  • dynamin 1 (DNM1)
  • dynamin 1 (Dnm1)
  • dynamin-1-like (LOC100199205)
  • dynamin 1a (dnm1a)
  • dynamin-1-like protein (EHI_013180)
  • dynamin-1-like protein (EHI_131670)
  • dynamin 1-like (DNM1L)
  • AI838169 protein
  • Dnm protein
  • dnm1 protein
  • Ftfl protein
  • mKIAA4093 protein
  • si:dkey-246l19.2 protein

Protein level used designations for Dynamin 1 Proteins (DNM1)

dynamin-1 , dynamin 1 , dynamin-1-like , dynamin-1-like protein , B-dynamin , D100 , dynamin, brain , dynamin-1-like protein-like

6166902 Oikopleura dioica
6346092 Pyrenophora tritici-repentis Pt-1C-BFP
6346375 Pyrenophora tritici-repentis Pt-1C-BFP
448130 Xenopus (Silurana) tropicalis
464766 Pan troglodytes
717697 Macaca mulatta
100070282 Equus caballus
100168088 Acyrthosiphon pisum
100199205 Hydra magnipapillata
100307098 Danio rerio
100388870 Callithrix jacchus
100470165 Ailuropoda melanoleuca
100544930 Meleagris gallopavo
100556614 Anolis carolinensis
100599465 Nomascus leucogenys
3403947 Entamoeba histolytica HM-1:IMSS
6220562 Entamoeba histolytica HM-1:IMSS
1759 Homo sapiens
13429 Mus musculus
140694 Rattus norvegicus
417217 Gallus gallus
508794 Bos taurus
491319 Canis lupus familiaris
100725033 Cavia porcellus
101108737 Ovis aries
100624497 Sus scrofa
477649 Canis lupus familiaris
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