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Browse our SAA1 Proteins (SAA1)

Full name:
Serum Amyloid A1 Proteins (SAA1)
On are 68 Serum Amyloid A1 (SAA1) Proteins from 12 different suppliers available. Additionally we are shipping SAA1 Antibodies (168) and SAA1 Kits (63) and many more products for this protein. A total of 304 SAA1 products are currently listed.
PIG4, SAA, Saa-1, SAA1, SAA2, TP53I4, zgc:103580
list all proteins Gene Name GeneID UniProt
SAA1 20208 P05366
SAA1 6288 P0DJI8

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SAA1 Proteins (SAA1) by Origin

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Top referenced SAA1 Proteins

  1. Mouse (Murine) SAA1 Protein expressed in Escherichia coli (E. coli) - ABIN1080801 : Belichenko, Madani, Rey-Bellet, Pihlgren, Becker, Plassard, Vuillermot, Giriens, Nosheny, Kleschevnikov, Valletta, Bengtsson, Linke, Maloney, Hickman, Reis, Granet, Mlaki, Lopez-Deber, Do, Singhal et al.: An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome. ... in PLoS ONE 2016 (PubMed)

More Proteins for SAA1 Interaction Partners

Mouse (Murine) Serum Amyloid A1 (SAA1) interaction partners

  1. Data indicate that SAA1 overexpressing mice (TG) show significant deficits in social behaviors, including impaired social recognition and reduced social interaction. Study detected exogenous SAA1 expression in the brain of TG mice, implying that liver-derived SAA1 migrates to the brain. Results show an increase in the accumulation of the 87kDa form of Abeta (show APP Proteins) in TG mice compared to wild type mice.

  2. Mass spectrometry analysis of peptides derived from chemically crosslinked HDL (show HSD11B1 Proteins)-SAA particles detected multiple crosslinks between apoA1 (show APOA1 Proteins) and SAA, indicating close proximity (within 25 A) of these two proteins on the HDL (show HSD11B1 Proteins) surface, providing a molecular and structural mechanism for the simultaneous binding of heparin to apoA1 (show APOA1 Proteins) and SAA.

  3. The findings identify SR-BII (show SCARB2 Proteins) as a functional SAA receptor that mediates SAA uptake and contributes to its proinflammatory signaling via the MAPK (show MAPK1 Proteins)-mediated signaling pathways.

  4. Sustained, elevated levels of SAA1 were correlated with metabolic parameters and local cytokine expression in the liver following 16 weeks on the high-fat diet. We suggest that SAA1-derived amyloid deposition under long-term high-fat diet exposure may be associated with the complications of high-fat diet-induced obesity and metabolic disorders.

  5. SAA inhibits osteoclast formation from mouse macrophages. SAA blocks RANKL (show TNFSF11 Proteins)-induced osteoclastogenesis.

  6. Serum Amyloid A induces inflammation, proliferation and cell death in activated hepatic stellate cells.

  7. These data demonstrate that SAA stimulates a robust pro-inflammatory response in skeletal muscle myotubes via the TLR2-dependent release of IL-6 (show IL6 Proteins) and TNFalpha (show TNF Proteins).

  8. Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL (show HSD11B1 Proteins)

  9. SAA1/2 produced by macrophages promotes early lesion formation in the ascending aorta in LDLR (show LDLR Proteins) knockout mice.

  10. Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Proteins) via TLR2 and directly synergizes with this chemokine (show CCL1 Proteins) via CXCR2 (show CXCR2 Proteins) and formyl peptide receptor 2 (show FPR2 Proteins) to recruit neutrophils.

Human Serum Amyloid A1 (SAA1) interaction partners

  1. Serum amyloid A could represent a novel marker of primary unexplained recurrent early pregnancy loss because affected women exhibited elevated levels of this protein.

  2. The polymorphism of SAA1 is not associated with susceptibility and severity of Familial Mediterranean Fever (show MEFV Proteins) in Egyptian children

  3. The findings identify SR-BII (show SCARB2 Proteins) as a functional SAA receptor that mediates SAA uptake and contributes to its proinflammatory signaling via the MAPK (show MAPK1 Proteins)-mediated signaling pathways.

  4. Correlate MEFV (show MEFV Proteins) genotype and the SAA1 polymorphisms with the clinical manifestations of familial Mediterranean fever (show MEFV Proteins) and the occurrence of amyloidosis in a large cohort of Armenian patients.

  5. Study found increased SAA concentration in patients with sarcoidosis.

  6. the detection of residues 76 and 77 of SAA (AA76) may alter the ability to diagnose AA amyloidosis.

  7. The results demonstrated that SAA upregulated Visfatin (show NAMPT Proteins) expression in cultured RAW264.7 macrophages and in the primary monocytes.

  8. Structure, function and SAA1 gene polymorphisms

  9. Serum Amyloid A induces inflammation, proliferation and cell death in activated hepatic stellate cells.

  10. Amyloid A overexpressed in renal cell carcinoma (show MOK Proteins) patients and can serve as a prognostic marker.

Cow (Bovine) Serum Amyloid A1 (SAA1) interaction partners

  1. polymorphisms in the SAA2 gene are associated with milk production traits in Chinese Holstein cows

Horse (Equine) Serum Amyloid A1 (SAA1) interaction partners

  1. endometritis gives rise to a systemic acute phase response and an up-regulated endometrial gene expression of SAA and several pro-and anti-inflammatory cytokines

  2. The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.

SAA1 Protein Profile

Protein Summary

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.

Alternative names and synonyms associated with SAA1

  • serum amyloid A1 (SAA1)
  • serum amyloid A (saa)
  • serum amyloid A protein (Sden_2438)
  • serum amyloid A protein (Mmc1_0571)
  • serum amyloid a protein (Riean_0971)
  • serum amyloid A 1 (Saa1)
  • serum amyloid A cluster (Saa)
  • serum amyloid A-3 (SAA3)
  • serum amyloid A-like 1 (SAAL1)
  • serum amyloid A1 (SAA)
  • serum amyloid A2 (SAA2)
  • serum amyloid protein A (LOC100009168)
  • PIG4 protein
  • SAA protein
  • Saa-1 protein
  • SAA1 protein
  • SAA2 protein
  • TP53I4 protein
  • zgc:103580 protein

Protein level used designations for Serum Amyloid A1 Proteins (SAA1)

serum amyloid A protein , saa1 , serum amyloid A1 , serum amyloid a protein , serum amyloid A 2 , serum amyloid A-1 protein , serum amyloid A , serum amyloid A-3 protein , tumor protein p53 inducible protein 4 , serum amyloid A2

403585 Canis lupus familiaris
449557 Danio rerio
480749 Canis lupus familiaris
751814 Canis lupus familiaris
4018937 Shewanella denitrificans OS217
4481493 Magnetococcus marinus MC-1
10001727 Riemerella anatipestifer ATCC 11845 = DSM 15868
20208 Mus musculus
111345 Mus musculus
100009138 Oryctolagus cuniculus
100341988 Oryctolagus cuniculus
6288 Homo sapiens
616035 Bos taurus
678660 Felis catus
100033905 Equus caballus
476879 Canis lupus familiaris
100034017 Equus caballus
694827 Macaca mulatta
506412 Bos taurus
100009168 Oryctolagus cuniculus
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