SAA1 Protein (His tag)

Catalog No. ABIN7319028

Product Details

Target: SAA1 (Serum Amyloid A1 (SAA1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SAA1 protein is labelled with His tag.

Purpose: Recombinant Human Serum Amyloid A1/SAA1 Protein (His Tag)

Sequence: Arg19-Tyr122

Characteristics: Recombinant Human Serum Amyloid A1 Protein is produced by our E.coli expression system and the target gene encoding Arg19-Tyr122 is expressed with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM EDTA, pH 8.0.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SAA1 (Serum Amyloid A1 (SAA1))

Alternative Name: Serum Amyloid A1/SAA1 (SAA1 Products)

Synonyms: PIG4 Protein, SAA Protein, SAA2 Protein, TP53I4 Protein, zgc:103580 Protein, SAA1 Protein, Saa-1 Protein, Saa2 Protein, serum amyloid A1 Protein, serum amyloid A Protein, amyloid protein A Protein, serum amyloid A protein Protein, serum amyloid a protein Protein, serum amyloid A 1 Protein, serum amyloid protein A Protein, SAA1 Protein, saa Protein, LOC694827 Protein, Sden_2438 Protein, Mmc1_0571 Protein, Riean_0971 Protein, Saa1 Protein, LOC100009168 Protein, LOC101120204 Protein

Background:

Background: Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the HDL complex. The SAA cleavage product designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis, they disrupt tissue structure and compromise performance.

Synonym: Serum Amyloid A-1 Protein, SAA, SAA1

Molecular Weight: 13.2 kDa

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades