Browse our anti-IRX3 (IRX3) Antibodies

On are 93 Iroquois Homeobox 3 (IRX3) Antibodies from 16 different suppliers available. Additionally we are shipping IRX3 Proteins (5) and many more products for this protein. A total of 108 IRX3 products are currently listed.
AI894186, iro3, IRX-1, irx3b, IRXB1, xiro-3, xiro3
list all antibodies Gene Name GeneID UniProt
IRX3 307721  
IRX3 79191 P78415
IRX3 16373 P81067

Most Popular Reactivities for anti-IRX3 (IRX3) Antibodies

anti-Rat (Rattus) IRX3 Antibodies:

anti-Human IRX3 Antibodies:

anti-Mouse (Murine) IRX3 Antibodies:

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More Antibodies against IRX3 Interaction Partners

Human Iroquois Homeobox 3 (IRX3) interaction partners

  1. Increased adipocyte-specific expression of IRX3 correlates with the presence of the FTO obesity risk haplotype in lean children, whereas it was unaffected by risk variants in obese peers. IRX3 expression in adipocytes was significantly related to adipocyte hypertrophy.

  2. the association between FTO and obesity appears to be due to its influence on expression of IRX3 [Figure 1]. Genetic studies indicated FTO as an important gene for obesity risk in various populations but the recent developments suggest that obesity-associated FTO SNPs have long-range interactions with IRX3.

  3. Downregulation of miR (show MLXIP Antibodies)-377 may contribute to the upregulation of IRX3 in HCC (show FAM126A Antibodies).

  4. This is the first study to reveal that genetic variants of both FTO and IRX3 genes are in high linkage disequilibrium (LD) and are associated with obesity risk in North Indians.

  5. Strategies to pharmacologically regulate Irx3 function in adult endothelial cells may provide new therapies for angiogenesis.

  6. data suggest that IRX3 is a functional long-range target of obesity-associated variants within FTO (show FTO Antibodies) and represents a novel determinant of body mass and composition

  7. IRX3 function may have a direct functional relationship to both obesity and type 2 diabetes.

Xenopus laevis Iroquois Homeobox 3 (IRX3) interaction partners

  1. barH-like homeobox-2 (show BARHL2 Antibodies) gene barhl2 (show BARHL2 Antibodies) acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal (show CAD Antibodies) forebrain signaling center induced by Sonic Hedgehog (show SHH Antibodies)

  2. Irx3 is transcriptionally induced by the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway during anteroposterior patterning of the neural axis.

  3. Irx3 is the first gene known to be necessary and sufficient to specify nephron segment fate in vivo.

Mouse (Murine) Iroquois Homeobox 3 (IRX3) interaction partners

  1. Irx3 is necessary for the postnatal maturation of the VCS (show EDC4 Antibodies), possibly via its interactions with Tbx5 (show TBX5 Antibodies) and Nkx2.5 (show NKX2-5 Antibodies).

  2. Irx3 and Irx5 (Irx3/5) are essential in the initiating limb bud to specify progenitors of the femur, tibia, and digit 1.

  3. data suggest that IRX3 is a functional long-range target of obesity-associated variants within FTO (show FTO Antibodies) and represents a novel determinant of body mass and composition

  4. postnatal Irx3 activity can be repressed by Irx5 (show IRX5 Antibodies)

  5. Irx3 is critical for efficient conduction in this specialized tissue by antithetically regulating two gap junction-forming connexins

  6. Irx3 signal is restricted to the somatic cell component of XX gonads and is present at a discreet period of ovarian development that ends at birth.

IRX3 Antigen Profile

Antigen Summary

IRX3 is a member of the Iroquois homeobox gene family (see IRX1\; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998

Alternative names and synonyms associated with IRX3

  • iroquois homeobox 3 (IRX3) antibody
  • iroquois homeobox 3 (Irx3) antibody
  • iroquois homeobox 3 (irx3) antibody
  • Iroquois related homeobox 3 (Drosophila) (Irx3) antibody
  • AI894186 antibody
  • iro3 antibody
  • IRX-1 antibody
  • irx3b antibody
  • IRXB1 antibody
  • xiro-3 antibody
  • xiro3 antibody

Protein level used designations for IRX3

iroquois homeobox protein 3 , iroquois-class homeodomain protein IRX-3 , Iroquois related homeobox 3 , homeodomain protein IRXB1 , iroquois-class homeodomain protein IRX-1 , Iroquois homeobox protein 3 , homeobox transcription factor iroquois 3 , iroquois type homeobox , iroquois-class homeodomain protein irx-3

487277 Canis lupus familiaris
540417 Bos taurus
307721 Rattus norvegicus
79191 Homo sapiens
399365 Xenopus laevis
16373 Mus musculus
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