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Browse our anti-VHL (VHL) Antibodies

Full name:
anti-Von Hippel-Lindau Tumor Suppressor Antibodies (VHL)
On www.antibodies-online.com are 16 Von Hippel-Lindau Tumor Suppressor (VHL) Antibodies from 2 different suppliers available. Additionally we are shipping VHL Kits (2) and and many more products for this protein. A total of 20 VHL products are currently listed.
Synonyms:
BcDNA:RH61560, CG13221, d-vhl, Dmel\\CG13221, dmVHL, dVHL, hrca1, rca1, vhl, vhl1, Vhlh, zgc:158722
list all antibodies Gene Name GeneID UniProt
VHL 24874 Q64259
VHL 22346 P40338
VHL    

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Most Popular Reactivities for anti-VHL (VHL) Antibodies

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anti-Rat (Rattus) VHL Antibodies:

anti-Mouse (Murine) VHL Antibodies:

anti-Human VHL Antibodies:

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More Antibodies against VHL Interaction Partners

Fruit Fly (Drosophila melanogaster) Von Hippel-Lindau Tumor Suppressor (VHL) interaction partners

  1. Interaction between Nm23 (show NME1 Antibodies) and the tumor suppressor VHL

  2. Transgenic pVHL can fully maintain normal dVHL-HIF1-alpha (show HIF1A Antibodies) downstream pathways in flies.

  3. Codepletion of Vhl with Mgr (show GRHL1 Antibodies) gives partial rescue of tubulin (show TUBB Antibodies) instability, monopolar spindle formation, and loss of centrosomes.

  4. The results establish a developmental function of the VHL gene that is relevant to its tumor-suppressor activity.

  5. findings reveal a second type of tracheal hypoxic response in which Sima activation conflicts with developmental tracheogenesis, and identify the dVHL and ago ubiquitin ligases as key determinants of hypoxia sensitivity in tracheal cells

Zebrafish Von Hippel-Lindau Tumor Suppressor (VHL) interaction partners

  1. Zebrafish embryos lacking endogenous vhl lead to defective phenotypes in the renal system that were characterized by the curved and cystic pronephric tubule or/and a cystic and malformed glomerulus.

  2. Inhibiting PHD (show PDC Antibodies) or knocking down VHL rescues Methyl tert (show TERT Antibodies)-butyl ether induced vascular lesions.

  3. Zebrafish vhl mutants display a marked increase in blood vessel formation throughout the embryo, and the most severe neovascularization is observed in distinct areas that overlap with high vegfa (show VEGFA Antibodies) mRNA expression, including the vhl mutant brain and eye.

  4. Vhl mutants develop polycythemia with increased epo (show EPO Antibodies)/epor (show EPOR Antibodies) mRNA & erythropoietin (show EPO Antibodies) signaling. VHL regulates hematopoiesis & erythroid differentiation. Zebrafish vhl mutants are the 1st congenital embryonic viable systemic vertebrate animal model for VHL.

Mouse (Murine) Von Hippel-Lindau Tumor Suppressor (VHL) interaction partners

  1. Loss of Vhl in mesenchymal progenitors of the limb bud caused severe fibrosis of the synovial joints and formation of aggressive masses with histologic features of mesenchymal tumors.

  2. These data suggested that intestinal epithelial cells were injured after IM treatment through the pVHL overexpression-induced degradation of collagen I or HIF-1alpha (show HIF1A Antibodies).

  3. Vhl and Kif3a (show KIF3A Antibodies) deletion accelerates renal cyst formation

  4. maintains the stability and suppressive function of Foxp3 (show FOXP3 Antibodies)+ T cells via regulation of HIF-1a (show HIF1A Antibodies) pathway

  5. Deletion of the Vhl gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.

  6. Molecular dynamics of hif-1alpha (show HIF1A Antibodies) and VHL may determine the success of antineoplastic strategies in hypoxia-reoxygenation as predicted by computational modeling.

  7. Loss of Vhl in adult joint cartilage is associated with earlier dysregulation of cartilage homeostasis, characterized by increased chondrocyte apoptosis, compromised chondrocyte autophagy and accelerated age-related and surgery-induced OA development.

  8. Both Vhl and Bap1 (show BAP1 Antibodies) are required for kidney function. Even when Vhl is inactivated in multipotent nephron progenitor cells, Vhl loss is insufficient for renal tumorigenesis.

  9. VHL deficiency perturbs pancreas endocrine homeostasis in mice.

  10. data suggest that the VHL-mediated signaling in osteochondral progenitor cells plays a critical role in bone remodeling at postnatal/adult stages through coupling osteogenesis and angiogenesis

VHL Antigen Profile

Antigen Summary

may act as a tumor suppressor

Alternative names and synonyms associated with VHL

  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (Vhl) antibody
  • von Hippel-Lindau (Vhl) antibody
  • von Hippel-Lindau tumor suppressor (VHL) antibody
  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (vhl) antibody
  • von Hippel-Lindau tumor suppressor (vhl) antibody
  • von Hippel-Lindau disease tumor suppressor (CpipJ_CPIJ009992) antibody
  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (VHL) antibody
  • von Hippel-Lindau tumor suppressor (Vhl) antibody
  • BcDNA:RH61560 antibody
  • CG13221 antibody
  • d-vhl antibody
  • Dmel\\CG13221 antibody
  • dmVHL antibody
  • dVHL antibody
  • hrca1 antibody
  • rca1 antibody
  • vhl antibody
  • vhl1 antibody
  • Vhlh antibody
  • zgc:158722 antibody

Protein level used designations for VHL

pVHL , von Hippel-Lindau disease tumor suppressor , von Hippel-Lindau syndrome homolog , CG13221-PA , CG13221-PB , Vhl-PA , Vhl-PB , von hippel lindau , von hippel lindau protein , von Hippel-Lindau tumor suppressor , Von Hippel-Lindau disease tumor suppressor , von Hippel-Lindau syndrome protein homolog

GENE ID SPECIES
24874 Rattus norvegicus
53433 Drosophila melanogaster
416117 Gallus gallus
540957 Bos taurus
549121 Xenopus (Silurana) tropicalis
791202 Danio rerio
6042662 Culex quinquefasciatus
100173372 Pongo abelii
100380306 Salmo salar
22346 Mus musculus
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