Browse our Adenomatous Polyposis Coli (APC) ELISA Kits

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Adenomatous Polyposis Coli ELISA Kits (APC)
On www.antibodies-online.com are 18 Adenomatous Polyposis Coli (APC) ELISA Kits from 10 different suppliers available. Additionally we are shipping Adenomatous Polyposis Coli Antibodies (201) and Adenomatous Polyposis Coli Proteins (4) and many more products for this protein. A total of 238 Adenomatous Polyposis Coli products are currently listed.
Synonyms:
AI047805, APC1, AU020952, AW124434, BTPS2, CC1, DP2, DP2.5, DP3, fap, fpc, GS, mAPC, Min, PPP1R46, RATAPC, xapc
list all ELISA KIts Gene Name GeneID UniProt
APC 11789  
APC 324 P25054
APC 24205 P70478

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Adenomatous Polyposis Coli (APC) ELISA Kits by Reactivity

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Mouse (Murine) Adenomatous Polyposis Coli (APC) interaction partners

  1. Msi-1 (show MSI1 ELISA Kits) contributes to intestinal tumorigenesis driven by Apc loss, and validate the pursuit of Msi-1 (show MSI1 ELISA Kits) inhibitors as chemo-prevention agents to reduce tumor burden.

  2. APC haploinsufficiency coupled with p53 (show TP53 ELISA Kits) deletion resulted in the development of a distinct type of pancreatic premalignant precursors, mucinous cystic neoplasms (MCNs)

  3. Gasdermin C is upregulated by inactivation of Tgfbr2 (show TGFBR2 ELISA Kits) in the presence of mutated Apc, promoting colorectal cancer cell proliferation.

  4. By sequencing Apc and Ctnnb1 (show CTNNB1 ELISA Kits) genes, we found that most PhIP (show PHIP ELISA Kits)-induced small intestinal tumors in obese mice carried only a single heterozygous mutation in Apc . Our findings demonstrate that PhIP (show PHIP ELISA Kits)-induced small intestinal carcinogenesis in hCYP1A-db/db (show LEPR ELISA Kits) mice is promoted by obesity and involves Apc mutation and inactivation by DNA hypermethylation

  5. Elevated coexpression of KITENIN (show Vangl1 ELISA Kits) and ErbB4 (show ERBB4 ELISA Kits)-CYT (show CYGB ELISA Kits)-2 promotes the transition of colon adenoma to adenocarcinoma within an APC loss-associated tumor microenvironment

  6. The activation of canonical Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling by deletion of Apc in cardiomyocytes led to ventricular hyperplasia.

  7. demonstrated that despite having both Kras and Pik3ca (show PIK3CA ELISA Kits) mutations at the time of tumor initiation from loss of APC

  8. Suggest that the early activation of Hsf1 (show HSF1 ELISA Kits) dependent cell stress pathway by mono-allelic mutations in APC can affect cell programming in a way that contributes to cancer onset.

  9. Adenomatous polyposis coli mutation leads to myopia development in mice.

  10. findings indicate Ctnnb1 (show CTNNB1 ELISA Kits) gene dose exerts tissue-specific differences in Apc mutation-instigated tumorigenesis

Human Adenomatous Polyposis Coli (APC) interaction partners

  1. Findings show that colorectal Cancer patients-derived cells with short APC mutants were either sensitive or responsive to tankyrase inhibitors corroborating the idea that APC with complete deletion of seven 20-AA repeats could be a predictive biomarker for the sensitivity to tankyrase inhibitors.

  2. Our study showed that mutations in the APC gene alter the protein expression and cell cycle regulation in diffuse type gastric adenocarcinoma.

  3. Gasdermin C is upregulated by inactivation of Tgfbr2 (show TGFBR2 ELISA Kits) in the presence of mutated Apc, promoting colorectal cancer cell proliferation.

  4. Nine patients with 21- approximately 100 colorectal adenomas (50%) and the two positive controls, showed somatic mosaicism, with identical APC variants in adenomas tested.

  5. These result suggested that miR (show MLXIP ELISA Kits)-590-3p can promote osteogenic differentiation via suppressing APC expression and stabilizing beta-catenin (show CTNNB1 ELISA Kits).

  6. The present findings indicate epigenetic silencing of APC in advanced gallbladder cancer (GBC). The methylation pattern, followed by expression analysis of APC may be suggested for diagnostic, prognostic and therapeutic purposes in GBC in future

  7. miR (show MLXIP ELISA Kits)-106a-5p is involved in the invasive behavior of glioblastoma cells and by targeting APC and activating Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway.

  8. Point Mutations in Exon 1B of APC Reveal Similar mutations in APC promoter 1B occur in rare families with familial adenomatous polyposis

  9. Studies suggest that both loss of tumor suppressive function and gain of function of APC mutants play critical roles in colorectal cancers (CRC (show CALR ELISA Kits)) tumorigenesis.

  10. Loss of heterozygosity of TP53 (show TP53 ELISA Kits), P16, SMAD4 (show SMAD4 ELISA Kits) and APC genes was observed in esophageal adenocarcinoma.

Xenopus laevis Adenomatous Polyposis Coli (APC) interaction partners

  1. the Amer2 (show AMER2 ELISA Kits)-EB1 (show MAPRE1 ELISA Kits)-APC complex regulates cell migration by altering microtubule stability.

  2. Data show that importin-beta (show KPNB1 ELISA Kits) binds to Apc and negatively regulates the MT-assembly and spindle-promoting activity of Apc in a Ran-regulatable manner.

  3. APC and Axin (show AXIN1 ELISA Kits) are involved in the Wnt (show WNT2 ELISA Kits) pathway

  4. depletion of APC from cystostatic factor (CSF (show CSF2 ELISA Kits)) Xenopus extracts leads to a decrease in microtubule density and changes in tubulin (show TUBB ELISA Kits) distribution in spindles and asters formed in such extracts

  5. An interaction of tumor-associated N-terminal APC fragments (N-APC) with Mad2 (show MAD2L1 ELISA Kits), an essential mitotic checkpoint (show BUB3 ELISA Kits) protein, providing a direct molecular support for linking APC mutations to the generation of chromosome instability, is reported.

Adenomatous Polyposis Coli (APC) Antigen Profile

Antigen Summary

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Alternative names and synonyms associated with Adenomatous Polyposis Coli (APC)

  • adenomatous polyposis coli (APC) Elisa Kit
  • adenomatous polyposis coli (apc) Elisa Kit
  • adenomatous polyposis coli protein (Smp_139190) Elisa Kit
  • adenomatosis polyposis coli (Apc) Elisa Kit
  • adenomatous polyposis coli (Apc) Elisa Kit
  • AI047805 Elisa Kit
  • APC1 Elisa Kit
  • AU020952 Elisa Kit
  • AW124434 Elisa Kit
  • BTPS2 Elisa Kit
  • CC1 Elisa Kit
  • DP2 Elisa Kit
  • DP2.5 Elisa Kit
  • DP3 Elisa Kit
  • fap Elisa Kit
  • fpc Elisa Kit
  • GS Elisa Kit
  • mAPC Elisa Kit
  • Min Elisa Kit
  • PPP1R46 Elisa Kit
  • RATAPC Elisa Kit
  • xapc Elisa Kit

Protein level used designations for APC

adenomatosis polyposis coli , adenomatous polyposis coli protein , multiple intestinal neoplasia , adenomatosis polyposis coli tumor suppressor , deleted in polyposis 2.5 , protein phosphatase 1, regulatory subunit 46 , adenomatous polyposis coli homolog

GENE ID SPECIES
100064431 Equus caballus
461999 Pan troglodytes
479139 Canis lupus familiaris
779466 Xenopus (Silurana) tropicalis
8350424 Schistosoma mansoni
11789 Mus musculus
324 Homo sapiens
24205 Rattus norvegicus
100517932 Sus scrofa
533233 Bos taurus
399455 Xenopus laevis
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