Browse our FZD1 Proteins (Fzd1)

Full name:
Frizzled Family Receptor 1 Proteins (Fzd1)
On are 12 Frizzled Family Receptor 1 (Fzd1) Proteins from 5 different suppliers available. Additionally we are shipping FZD1 Antibodies (109) and FZD1 Kits (12) and many more products for this protein. A total of 136 FZD1 products are currently listed.
AW227548, cFz-1, CG3646, CG17697, DFz, Dfz1, Dmel\\CG17697, Dm Fz1, frizzled1, frz, frz-1, frz1, Fz, FZ-1, fz1, fzd1-A, fz[[1]], Xfrizzled-1
list all proteins Gene Name GeneID UniProt
Fzd1 8321 Q9UP38
Rat Fzd1 Fzd1 58868  
Fzd1 14362 O70421

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FZD1 Proteins (Fzd1) by Origin

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Top referenced FZD1 Proteins

  1. Mouse (Murine) FZD1 Protein expressed in Human Cells - ABIN2007308 : Sagara, Toda, Hirai, Terada, Katoh: Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7. in Biochemical and biophysical research communications 1998 (PubMed)
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More Proteins for FZD1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Frizzled Family Receptor 1 (Fzd1) interaction partners

  1. instructive input of Frizzled-Planar cell polarity (Fz/PCP (show PRCP Proteins)) signalling into polarized centriole positioning in Drosophila wings, is reported.

  2. Studies indicate that Frizzled (Fz) is constitutively ubiquitinated and internalized to the early endosome.

  3. We found no evidence for an essential requirement of the Fz C-terminal tail downstream of the KTxxxW motif in planar polarity and canonical Wnt (show WNT4 Proteins) signaling.

  4. Frizzled-dependent planar polarity pathway locally promotes E-cadherin (show CDH1 Proteins) turnover via recruitment of RhoGEF2.

  5. Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity.

  6. Frizzled and Dishevelled (show DVL2 Proteins) are enriched at distal sides of each cell and hence localize at the interface with ligand-expressing cells in the non-responding cells.

  7. Knockdown of Tc-fz1 (show FZD4 Proteins) alone interfered with the formation of the proximo-distal and the dorso-ventral axes during leg development, whereas no effect was observed with single Tc-fz2 (show FZD2 Proteins) or Tc-fz4 (show FZD4 Proteins) RNAi knockdowns.

  8. Results describe a Frizzled-Dishevelled (show DVL2 Proteins)-NuMA/Mud (show AP5M1 Proteins) pathway that orients division from Drosophila to vertebrates.

  9. dAbl positively regulates the Fz/Dishevelled (Dsh (show DVL2 Proteins)) PCP (show PRCP Proteins) pathway without affecting canonical Wnt/Wg-Fz signaling

  10. A balance of ubiquitylation and deubiquitylation of the Wg/Wnt receptor Frizzled determines the cellular responsiveness to Wg/Wnt both in mammalian cells and in Drosophila.

Human Frizzled Family Receptor 1 (Fzd1) interaction partners

  1. aken together, our results suggest that Sp1 (show PSG1 Proteins) plays a role in human osteoblast differentiation and mineralization, which is at least partially mediated by Sp1 (show PSG1 Proteins)-dependent transactivation of FZD1.

  2. The amplification of miR (show MLXIP Proteins)-135b suppressed non-small cell lung cancer chemoresistance by directly mediating FZD1 down-regulation.

  3. Our study suggests that Sox9 (show SOX9 Proteins) siRNA inhibits the proliferation capability of human osteosarcoma cells by down-regulating the expression of Wnt1 (show WNT1 Proteins) and its receptor Fzd1

  4. FZD1 expression was down-regulated by AP2 (show GTF3A Proteins) expression and mediated osteoblast differentiation and mineralization.

  5. our data demonstrate that FZD1 regulates PKCdelta (show PKCd Proteins), and the PKCdelta (show PKCd Proteins)/AP-1 (show FOSB Proteins) signalling transduction pathway plays an important role in drug resistance in MES (show ME1 Proteins)-SA/Dx5 (show ITGA2 Proteins) cells.

  6. Polymorphisms in several genes involved in the Wnt (show WNT2 Proteins) signaling pathway were associated with hepatic fibrosis or inflammation risk in HCV-infected males.

  7. ACE2 (show ACE2 Proteins) and FZD1 are prognosis markers in squamous cell/adenosquamous carcinoma and adenocarcinoma of gallbladder.

  8. Experiments demonstrate a role of E2F1 (show E2F1 Proteins) in osteoblast differentiation and mineralization and suggest that FZD1 is required, in part, for E2F1 (show E2F1 Proteins) regulation of osteoblast mineralization.

  9. Fz1 (show FZD4 Proteins) is a Wnt (show WNT2 Proteins) responsive gene in colon-derived tissues. Fz1 (show FZD4 Proteins) expression exhibited increased expression in normal mucosa only in close proximity to colon cancer

  10. FZD1 appears to mediate multidrug resistance by regulating the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway

Mouse (Murine) Frizzled Family Receptor 1 (Fzd1) interaction partners

  1. FZD1 regulates specific stages of adult hippocampal neurogenesis.

  2. Suppressed expression of Fzd1 in myogenic cells from aged mice results in a significant increase in myogenic differentiation, and its forced expression in those from young mice results in its drastic inhibition.

  3. The results indicate the involvement of Wnt1 (show WNT1 Proteins) and Fzd1 in the pathogenesis and development of amyotrophic lateral sclerosis.

  4. Wnt (show WNT2 Proteins)/Fzd signaling is involved in balancing the inflammatory response to microbial stimulation of innate immune cells of vertebrate origin

  5. Frizzled signaling is involved in diverse tissue closure processes, defects in which account for some of the most common congenital anomalies.

  6. Indicate that myofibroblast migration and differentiation are modulated via Wnt (show WNT2 Proteins)/Fzd signalling.

  7. Fz-1 is expressed at distinct stages of follicular development.

  8. Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95. "FZ-2, Fz-4, Fz-7"

  9. Frizzled-1 is an antagonist of the canonical Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway

  10. Data demonstrate that Wnt7b (show WNT7B Proteins) signals through Fzd1 and -10 and LRP5 (show LRP5 Proteins) and implicate these Wnt (show WNT2 Proteins) coreceptors in the regulation of lung airway and vascular development.

FZD1 (Fzd1) Protein Profile

Protein Summary

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.

Alternative names and synonyms associated with FZD1 (Fzd1)

  • frizzled (fz)
  • frizzled family receptor 1 (FZD1)
  • frizzled family receptor 1 (Fzd1)
  • frizzled family receptor 1 (fzd1)
  • frizzled homolog 1 (Drosophila) (Fzd1)
  • AW227548 protein
  • cFz-1 protein
  • CG3646 protein
  • CG17697 protein
  • DFz protein
  • Dfz1 protein
  • Dmel\\CG17697 protein
  • Dm Fz1 protein
  • frizzled1 protein
  • frz protein
  • frz-1 protein
  • frz1 protein
  • Fz protein
  • FZ-1 protein
  • fz1 protein
  • fzd1-A protein
  • fz[[1]] protein
  • Xfrizzled-1 protein

Protein level used designations for Fzd1

CG17697-PA , CG17697-PB , CG17697-PC , Frizzled1 , frazzled , frizzled 1 , frizzled[[1]] , fz-PA , fz-PB , fz-PC , frizzled 1, seven transmembrane spanning receptor , frizzled homolog 1 , Wnt receptor , frizzled, Drosophila, homolog of, 1 , frizzled-1 , fz-1 , fzE1 , hFz1 , 7-transmembrane protein frizzled-1 , Drosophila polarity gene (frizzled) homologue , Drosophila polarity gene homolog 1 , rFz1 , 7-transmembrane receptor frizzled-1 , xfz1 , mFz1

45307 Drosophila melanogaster
463524 Pan troglodytes
8321 Homo sapiens
374062 Gallus gallus
58868 Rattus norvegicus
373817 Xenopus laevis
14362 Mus musculus
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