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Browse our anti-GSK3 beta (GSK3b) Antibodies

Full name:
anti-Glycogen Synthase Kinase 3 beta Antibodies (GSK3b)
On www.antibodies-online.com are 2 Glycogen Synthase Kinase 3 beta (GSK3b) Antibodies from 1 different suppliers available. A total of 2 GSK3 beta products are currently listed.
Synonyms:
7330414F15Rik, 8430431H08Rik, C86142, fk80d11, gsk-3, GSK-3beta, GSK-3[b], gsk3, gsk3-beta, GSK3beta, wu:fb68h05, wu:fk80d11, xgsk-3
list all antibodies Gene Name GeneID UniProt
GSK3b 56637 Q9WV60
GSK3b 84027 P18266
GSK3b 2932 P49841

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Most Popular Reactivities for anti-GSK3 beta (GSK3b) Antibodies

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anti-Mouse (Murine) GSK3 beta Antibodies:

anti-Rat (Rattus) GSK3 beta Antibodies:

anti-Human GSK3 beta Antibodies:

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More Antibodies against GSK3 beta Interaction Partners

Mouse (Murine) Glycogen Synthase Kinase 3 beta (GSK3b) interaction partners

  1. results suggest that GSK3 may in part modulate the hypertonic-induced intracellular UT-A1 (show SLC14A2 Antibodies) redistribution and its accumulation on the plasma membrane, which may constitute another mechanism by which GSK3 modulates urine concentration

  2. observations revealed that the alteration of PKB-GSK-3beta axis, Plk-1, and Aurora kinase-A expressions in HSPC compartment due to DNA damage response was associated with the proliferative impairment and apoptosis during aplastic anemia.

  3. Voluntary exercise produces a lasting protective state in the hippocampus, maintained in hippocampal slices by a PI3K-dependent mechanism that precludes its functional disruption in the presence of Abeta (show APP Antibodies) by avoiding GSK3beta activation

  4. The GSK-3beta activity increased, and expression of beta-catenin (show CTNNB1 Antibodies) decreased significantly in the hippocampus of the chronic intermittent hypoxia exposed mice.

  5. GSK3b may up-regulate BK channels, an effect disrupted by lithium or additional expression of AKT (show AKT1 Antibodies) and possibly participating in the regulation of cell volume and excitability.

  6. Cadmium induces cell death on cholinergic neurons through blockade of M1 receptor, overexpression of AChE-S and GSK-3beta, down-regulation of AChE-R and increase in Abeta (show APP Antibodies) and total and phosphorylated tau protein levels.

  7. These results reveal a key role of the AKT (show AKT1 Antibodies)-GSK3beta-eIF2Bepsilon (show EIF2B5 Antibodies) signaling module in regulating axon regeneration in the adult mammalian central nervous system.

  8. The GSK3 activity in mouse testes and sperm were quantifiable by gel shift assay with low sample consumption and were significantly correlated with the expression levels of GSK3 and p-GSK3. We suggest that our assay can be used for reliable and rapid detection of GSK3 activity in cells and tissue extracts.

  9. The predominant AKT (show AKT1 Antibodies) isoform in the central nervous system, AKT3 (show AKT3 Antibodies), induces much more robust axon regeneration than AKT1 (show AKT1 Antibodies) and that activation of mTORC1 and inhibition of GSK3beta are two critical parallel pathways for AKT (show AKT1 Antibodies)-induced axon regeneration.

  10. The expression of PI3K-insensitive GSK3 stimulates the production of adiponectin (show ADIPOQ Antibodies) and protects from diet-induced metabolic syndrome.

Human Glycogen Synthase Kinase 3 beta (GSK3b) interaction partners

  1. Data suggest that melatonin down-regulates adipogenesis via reduction of (a) cAMP synthesis, (b) reactive oxygen species synthesis, (c) phosphorylation of CEBPB (CCAAT-enhancer-binding protein-beta (show CEBPB Antibodies)), and (d) activation of GSK3B (glycogen synthase kinase 3 beta); primary mesenchymal stem cells cultured in adipogenic differentiation media were used in these studies.

  2. flavonoids from Diplotaxis harra display cytotoxic activity against inflammatory and cancer intestinal cells which could depend on GSK3beta inhibition.

  3. Low expression of GSK3B is associated with oral cancer.

  4. These data suggest that BIO, as an inhibitor of GSK-3beta, can suppress Ovarian cancer (OC) development. Therefore, BIO could be a candidate drug for the treatment of OC.

  5. This study suggested mechanistic relationship between miR (show MLXIP Antibodies)-940 and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) in the development and progression of pancreatic carcinoma through regulation of GSK3beta and sFRP1 (show SFRP1 Antibodies).

  6. data suggested that in response to Abeta (show APP Antibodies) exposure in SH-SY5Y cells, GSK3beta activation is performed through Tyr216 phosphorylation and resulted in tau phosphorylation at PHF-1 (show PHF1 Antibodies) epitope and in its translocation

  7. Sophocarpine could exert anti-tumor effects partly via downregulating the activity of the cancer stem cell AKT (show AKT1 Antibodies)-GSK3beta/catenin signaling pathways and inhibiting epithelial-mesenchymal transformation induced by TGF-beta (show TGFB1 Antibodies).

  8. High GSK3B expression is associated with pancreatic cancer.

  9. miR (show MLXIP Antibodies)-769 might act as a tumor promoter by targeting GSK3B during development of human melanoma.

  10. miR (show MLXIP Antibodies)-1303 promotes neuroblastoma (show ARHGEF16 Antibodies) (NB) proliferation by targeting GSK3beta and SFRP1 (show SFRP1 Antibodies), and might be a target for NB therapy.

Xenopus laevis Glycogen Synthase Kinase 3 beta (GSK3b) interaction partners

  1. Novel roles for Plk (show PLK1 Antibodies) and GSK3 regulation of ADAM13 (show ADAM33 Antibodies) function in cranial neural crest cell migration.

  2. Interaction with Snail1 (show SNAI1 Antibodies)/2, and Twist function more generally, is regulated by GSK-3-beta-mediated phosphorylation of conserved sites in the WR domain.

  3. These data suggest that the interactions of beta-catenin (show CTNNB1 Antibodies) with alpha-catenin (show CTNNA1 Antibodies) and GSK-3beta exert opposing effects on the terminal projections of ventral optic axons.

Zebrafish Glycogen Synthase Kinase 3 beta (GSK3b) interaction partners

  1. Both active and inactive forms of Gsk3b mediate the cooperative signaling during angiogenesis in zebrafish embryos.

  2. a novel negative, Gsk3beta-independent control mechanism of beta-catenin and implicates Ccr7 as a long-hypothesized GPCR regulating vertebrate axis formation.

  3. The regulatory target of Wnts and Igfs, GSK3beta, is inefficiently inactivated in male fin regenerates compared with females. Pharmacological inhibition of GSK3 in males increases blastemal proliferation and restores regenerative pattern.

  4. 2-OST (show HS2ST1 Antibodies) functions within the Wnt (show WNT2 Antibodies) pathway, downstream of Wnt (show WNT2 Antibodies) ligand signaling and upstream of Gsk3beta and beta-catenin (show CTNNB1 Antibodies) intracellular localization and function

  5. Data show that GSK-3beta inhibition was sufficient to stimulate MG dedifferentiation and the formation of multipotent retinal progenitors that were capable of differentiating into all major retinal cell types.

  6. GSK3alpha, but not GSK3beta, is necessary in cardiomyocyte survival

  7. Gsk3b regulates the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl (show SGPL1 Antibodies)) factor activity.

  8. A newly developed highly active GSK3beta inhibitor AR-534, reduced human TAU phosphorylation in TAU transgenic zebrafish.

Pig (Porcine) Glycogen Synthase Kinase 3 beta (GSK3b) interaction partners

  1. Five different isoforms of GSK3beta identified from porcine tissues, splice variants exhibit differential activity towards glycogen synthase.

  2. scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of GSK3beta activity which can lead to activation of the downstream signaling through beta-catenin (show CTNNB1 Antibodies)

  3. There was no correlation of infarct size with expression or phosphorylation of p70S6K (show RPS6KB1 Antibodies) or GSK3beta in ischemic postconditioning.

Cow (Bovine) Glycogen Synthase Kinase 3 beta (GSK3b) interaction partners

  1. GSK3B and phosphorylated GSK3B regulate milk synthesis and proliferation dairy cow mammary epithelial cells.

  2. GSK3B serine phosphorylation was positively correlated with embryo development

  3. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

  4. IGF-I (show IGF1 Antibodies) down-regulated functional IGF-I receptor (show IGF1R Antibodies) via GSK-3beta inhibition and mTOR (show FRAP1 Antibodies) activation; constitutive activity of GSK-3beta maintained IGF-I receptor (show IGF1R Antibodies) level in nonstimulated cells.

  5. These results suggest that phospholipids and sulfatide and heparin may function as effective stimulators for autophosphorylation of GSK-3beta and for the GSK-3beta-mediated phosphorylation of SH-binding proteins, including MBP (show MBP Antibodies) and tau protein.

  6. cAMP/PKA regulation of GSK3beta/beta-catenin (show CTNNB1 Antibodies) signaling contributes to the increase in progesterone production in corpus luteum.

GSK3 beta (GSK3b) Antigen Profile

Antigen Summary

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GSK3 beta (GSK3b)

  • glycogen synthase kinase 3 beta (Gsk3b) antibody
  • glycogen synthase kinase 3 beta (GSK3B) antibody
  • glycogen synthase kinase 3 beta (gsk3b) antibody
  • 7330414F15Rik antibody
  • 8430431H08Rik antibody
  • C86142 antibody
  • fk80d11 antibody
  • gsk-3 antibody
  • GSK-3beta antibody
  • GSK-3[b] antibody
  • gsk3 antibody
  • gsk3-beta antibody
  • GSK3beta antibody
  • wu:fb68h05 antibody
  • wu:fk80d11 antibody
  • xgsk-3 antibody

Protein level used designations for GSK3b

GSK-3 beta , glycogen synthase kinase-3 beta , serine/threonine-protein kinase GSK3B , FA , factor A , GSK3beta isoform , intracellular kinase , fb68h05 , glycogen synthase kinase 3 beta variant 1 , glycogen synthase kinase 3 beta variant 2 , glycogen synthase kinase 3 beta variant 3 , glycogen synthase kinase 3 beta variant 4 , GSK-3beta

GENE ID SPECIES
56637 Mus musculus
84027 Rattus norvegicus
2932 Homo sapiens
399097 Xenopus laevis
30654 Danio rerio
478575 Canis lupus familiaris
100126852 Sus scrofa
790875 Bos taurus
418335 Gallus gallus
100348842 Oryctolagus cuniculus
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