GSK3 beta antibody (AA 30-59)
Quick Overview for GSK3 beta antibody (AA 30-59) (ABIN3031094)
Target
See all GSK3 beta (GSK3b) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 30-59
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Purpose
- Gsk3b Antibody
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Cross-Reactivity (Details)
- Expected species reactivity: Human, Rat
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 30-59 from the mouse protein was used as the immunogen for this Gsk3b antibody.
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Isotype
- Ig Fraction
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anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibody
GSK3b Reactivity: Human, Mouse WB, IF, IP Host: Mouse Monoclonal 2E6-D6-C12 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 4-34), (N-Term) antibodyGSK3b Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB03816 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (N-Term) antibodyGSK3b Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 362-395) antibodyGSK3b Reactivity: Rat WB Host: Rabbit Polyclonal RB56577 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33) antibodyGSK3b Reactivity: Human, Rat WB Host: Rabbit Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33), (pSer9) antibodyGSK3b Reactivity: Human WB Host: Rabbit Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 4-34) antibodyGSK3b Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b Reactivity: Human, Mouse, Rat WB, IF, IP, ICC Host: Mouse Monoclonal 2E6-D6-C12 unconjugated
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Application Notes
- Titration of the Gsk3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Gsk3b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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Alternative Name
- Gsk3b
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Background
- Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
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UniProt
- Q9WV60
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Pathways
- WNT Signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
Target
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