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GSK3 beta antibody (AA 30-59)
The Rabbit Polyclonal anti-GSK3 beta antibody is suitable to detect GSK3 beta in samples from Mouse. It has been validated for WB, IHC and ELISA.
Catalog No. ABIN3031094
$612.54
Plus shipping costs $50.00
80 μL ABIN4954231
400 μL ABIN3031094
80 μL ABIN4954231
400 μL ABIN3031094
Delivery in 2 to 4 Business Days
Quick Overview for GSK3 beta antibody (AA 30-59) (ABIN3031094)
Target
See all GSK3 beta (GSK3b) Antibodies
GSK3 beta (GSK3b)
(Glycogen Synthase Kinase 3 beta (GSK3b))
Reactivity
All reactivities for GSK3 beta antibodies
Mouse
Host
All hosts for GSK3 beta antibodies
Rabbit
Clonality
All clonalities for GSK3 beta antibodies
Polyclonal
Conjugate
All conjugates for GSK3 beta antibodies
This GSK3 beta antibody is un-conjugated
Application
All applications for GSK3 beta antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Product Details anti-GSK3 beta Antibody
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Binding Specificity
All epitopes for GSK3 beta antibodies
AA 30-59
Purpose
Gsk3b Antibody
Cross-Reactivity (Details)
Expected species reactivity: Human, Rat
Purification
Antigen affinity
Immunogen
A portion of amino acids 30-59 from the mouse protein was used as the immunogen for this Gsk3b antibody.
Isotype
Ig Fraction
Alternatives
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Application Details
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Application Notes
Titration of the Gsk3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the Gsk3b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target Details for GSK3 beta
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Target
GSK3 beta (GSK3b)
(Glycogen Synthase Kinase 3 beta (GSK3b))
Alternative Name
Gsk3b
Background
Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
UniProt
Q9WV60
Pathways
WNT Signaling , Hedgehog Signaling , Fc-epsilon Receptor Signaling Pathway , Cellular Glucan Metabolic Process , ER-Nucleus Signaling , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Autophagy , BCR Signaling , Warburg Effect
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anti-GSK3 beta antibody (AA 30-59) (ABIN3031094)
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