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anti-Mouse (Murine) WNT5A Antibodies:
anti-Human WNT5A Antibodies:
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Human Polyclonal WNT5A Primary Antibody for FACS, IHC (p) - ABIN651869
He, Saint-Jeannet, Wang, Nathans, Dawid, Varmus: A member of the Frizzled protein family mediating axis induction by Wnt-5A. in Science (New York, N.Y.) 1997
Show all 4 references for ABIN651869
Human Monoclonal WNT5A Primary Antibody for ELISA, ICC - ABIN2869402
Dai, Hall, Escara-Wilke, Mizokami, Keller, Keller: Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms. in Cancer research 2008
Show all 3 references for ABIN2869402
Human Monoclonal WNT5A Primary Antibody for ELISA, IHC - ABIN2869410
Ford, Ekström, Andersson: Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells. in Proceedings of the National Academy of Sciences of the United States of America 2009
Show all 2 references for ABIN2869410
Dog (Canine) Polyclonal WNT5A Primary Antibody for IF (p), IHC (p) - ABIN675758
Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. in PLoS ONE 2014
Show all 2 references for ABIN675758
Chicken Polyclonal WNT5A Primary Antibody for IHC, WB - ABIN2779470
Witze, Litman, Argast, Moon, Ahn: Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors. in Science (New York, N.Y.) 2008
There is an important role of Wnt5a in kidney development. Disrupted Wnt5a results in kidney cysts in zebrafish and pleiotropic abnormal kidney development in mice.
Wnt5a acts as a chemoattractant in the emerging limb bud where it contributes to the establishment of cell polarity that is likely to underlie the oriented cell behaviours
Wnt5a deficiency can regulate inflammatory cytokine secretion, polarization, and apoptosis in MTB (show NCAPG2 Antibodies)-infected macrophage
These results showed that Wnt5a could promote the maturation of mast cells via the canonical Wnt (show WNT2 Antibodies) signaling pathway and provide important insights into the molecular mechanisms underlying the differentiation of mast cells
the CaMKK (show CAMKK2 Antibodies)-CaMKIalpha (show CAMK1 Antibodies) cascade is required for the axonal growth effect of Wnt5a during neuronal polarization.
Decreased expressions of Wnt1 (show WNT1 Antibodies) and Wnt5a.
indicate that restricted expression of Wnt5a in the caudal (show CAD Antibodies) SpM (show NPC1 Antibodies) is essential for normal OFT morphogenesis, and uncover a novel function of spatially regulated cell cohesion by Wnt5a in driving the deployment of SHF (show SHF Antibodies) cells from the SpM (show NPC1 Antibodies) into the OFT
Findings indicate wingless-related MMTV integration site 5A protein (WNT5a) as a key regulator of follicle development and gonadotropin responsiveness.
The oxidative stress of diabetes mellitus impairs Wnt (show WNT2 Antibodies) signaling and causes cardiac outlet defects that are rescued by SOD1 (show SOD1 Antibodies) overexpression
The results in a potent increase in odontoblastic cell differentiation, indicating the unique involvement of Atg5 (show ATG5 Antibodies), autophagy and Wnt5 signaling in CS/BMP-4 (show BMP4 Antibodies)-induced differentiation of ES cells into odontoblast-like cells, at a relatively early stage.
the Wnt5a/Frizzled-2 (show FZD2 Antibodies) axis suppresses beta-catenin (show CTNNB1 Antibodies) signaling in hepatocytes in an autocrine manner, thereby contributing to timely conclusion of the liver regeneration process
effects on hypoxic pulmonary hypertension by regulating pulmonary vascular remodeling and right ventricular hypertrophy via reduction in beta-catenin (show CTNNB1 Antibodies)/cyclin D1 (show CCND1 Antibodies) signaling
Xenopus adult stem cells originate from the larval absorptive cells expressing Ror2 (show ROR2 Antibodies), which require Wnt5a/Ror2 (show ROR2 Antibodies) signaling for their dedifferentiation accompanied by changes in cell morphology.
Data show that PAPC (show PCDH8 Antibodies) signaling via RhoA (show RHOA Antibodies) and Wnt5a/Ror2 (show ROR2 Antibodies) activity are required to keep cells aligned in apical-basal orientation during invagination of the ear placode.
Data show that Rspo3 (show RSPO3 Antibodies) binds syndecan 4 and that together they activate Wnt5a/PCP (show PRCP Antibodies) signaling.
In an examination of signaling pathways in developing Xenopus lung, wnt5a was expressed in the mesenchyme layer of the entire lungs through stages 39-41.
Wnt5a reduces cell surface levels and promotes ubiquitination and degradation of SDC4 (show SDC4 Antibodies) in dorsal mesodermal cells from Xenopus gastrulae.
Transcriptional regulation of XPAPC (show PCDH8 Antibodies) by XWnt-5A requires the receptor tyrosine kinase Ror2 (show ROR2 Antibodies).
Xwnt-5a plays an instructive role in larval tail regeneration via Wnt (show WNT2 Antibodies)/JNK (show MAPK8 Antibodies) signaling
Eosinophils enhance Wnt-5a, TGF-beta1 (show TGFB1 Antibodies), fibronectin (show FN1 Antibodies), and collagen gene expression in airway smooth muscle cells and promote proliferation of these cells in asthma.
86% of the ALL patients were hypermethylated in the WNT5A promoter region. Jurkat and RPMI cell lines were treated with 5'-aza-20-deoxycytidine and WNT5A mRNA expression was restored after treatment. Epigenetic changes of WNT (show WNT2 Antibodies) signaling can play a role in ALL pathogenesis
In this study, we explored the Wnt-5a binding site and designed an antigenic epitope on the MUC18 (show MCAM Antibodies) receptor using in silico methods. A specific single-chain variable fragment (scFv) was isolated against the epitope by several panning processes.The results suggest the specific anti-MUC18 (show MCAM Antibodies) scFv as an effective antibody for breast cancer immunotherapy
silencing of CerS6 (show CERS6 Antibodies) induced the increased expression of GLUT1 (show SLC2A1 Antibodies), which downregulated the expression of WNT5A and enhanced the invasion and proliferation of melanoma cells.
Study revealed a previously unrecognized immunomodulatory role of endogenous Wnt5A in ovarian cancer cells, which could further influence chemotactic cell migration.
Wnt5a is involved in the modulation of pancreatic cancer cell proliferation.
these findings suggest that miR154 functions as a tumor suppressor in osteosarcoma by partially suppressing Wnt5a expression.
Studied the roles of WNT4 (show WNT4 Antibodies) and WNT5A in human decidulization and their relationship with preeclampsia.
High WNT5A and WNT5B expression strongly associates with unmutated IGHV.
Wnt5a is increased and beta-catenin (show CTNNB1 Antibodies) is decreased in parenchyma from idiopathic pulmonary fibrosis patients.
WNT5A is a negative regulator of FSH (show BRD2 Antibodies)-stimulated granulosa cell steroidogenesis in cattle.
Wnt-5A may be associated with cartilage destruction by promoting the expression of matrix metalloproteinases.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
wingless-type MMTV integration site family, member 5A
, protein Wnt-5a
, protein Wnt-5a-like
, WNT-5A protein
, Wnt-5a protein
, wingless-related MMTV integration site 5A
, wingless-type MMTV integration site 5A