2'-5'-Oligoadenylate Synthetase-Like Proteins (OASL)

Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.. Additionally we are shipping OASL Antibodies (61) and OASL Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat OASL OASL 304545  
OASL 8638 Q15646
OASL    
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Top OASL Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg 11 Days
$291.50
Details
Escherichia coli (E. coli) Human S tag,His tag 100 μg 15 to 18 Days
$640.00
Details
Escherichia coli (E. coli) Human His tag   10 μg 15 to 16 Days
$300.00
Details

OASL Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for 2'-5'-Oligoadenylate Synthetase-Like (OASL) Interaction Partners

Human 2'-5'-Oligoadenylate Synthetase-Like (OASL) interaction partners

  1. these resulta define distinct mechanisms by which OASL differentially regulates host IFN responses during RNA and DNA virus infection and identify OASL as a negative-feedback regulator of cGAS

  2. These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen.

  3. OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth.

  4. Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 genes.

  5. these findings show a mechanism by which human OASL contributes to host antiviral responses by enhancing RIG-I activation.

  6. we propose that VSV treatment combined with the selective regulation of genes such as STAT1 and OASL2 will improve therapeutic outcomes for CUG2-overexpressing tumors

  7. variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits

  8. The pronounced difference in gene regulation between the OASL gene agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein.

  9. The expression of OASL and IFIT2 was significantly higher in SLE patients than in controls.

  10. OASLa, a major isoform of OASL induced in human liver, may mediate anti-HCV activity through two different domains.

  11. interaction with methyl CpG-binding protein 1 was confirmed in vitro and in vivo and was mapped to the ubiquitin-like domain of p59 OASL

  12. Proof that OASL is an antiviral protein that works through a novel mechanism distinct from other OASL proteins in other vertebrate species.

OASL Protein Profile

Protein Summary

Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.

Gene names and symbols associated with OASL

  • 2'-5'-oligoadenylate synthetase-like (Oasl)
  • 2'-5'-oligoadenylate synthetase like (OASL)
  • 2'-5'-oligoadenylate synthase-like protein (LOC100356242)
  • 2'-5'-oligoadenylate synthase-like protein (LOC100483471)
  • Oasl1 protein
  • OASLd protein
  • p59 OASL protein
  • p59-OASL protein
  • p59OASL protein
  • TRIP-14 protein
  • TRIP14 protein

Protein level used designations for OASL

2'-5' oligoadenylate synthetase-like 1 , 2'-5'-oligoadenylate synthase-like protein 1 , 59 kDa 2'-5'-oligoadenylate synthase-like protein , 2'-5'-OAS-RP , 2'-5'-OAS-related protein , 2'-5'-oligoadenylate synthase-like protein , 59 kDa 2'-5'-oligoadenylate synthetase-like protein , TR-interacting protein 14 , thyroid receptor-interacting protein 14 , 2'-5'-oligoadenylate synthetase-like , 59 kDa 2'-5'-oligoadenylate synthetase-like protein-like , 59 kDa 2'-5'-oligoadenylate synthase-like protein-like

GENE ID SPECIES
304545 Rattus norvegicus
8638 Homo sapiens
100356242 Oryctolagus cuniculus
100401503 Callithrix jacchus
100455196 Pongo abelii
100483471 Ailuropoda melanoleuca
100587823 Nomascus leucogenys
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