5'-Nucleotidase, Cytosolic II (NT5C2) ELISA Kits

NT5C2 encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. Additionally we are shipping 5'-Nucleotidase, Cytosolic II Antibodies (65) and 5'-Nucleotidase, Cytosolic II Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NT5C2 22978 P49902
Anti-Mouse NT5C2 NT5C2 76952 Q3V1L4
NT5C2 100363253  
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Top 5'-Nucleotidase, Cytosolic II ELISA Kits at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.128 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
€707.96
Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
€704.49
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More ELISA Kits for 5'-Nucleotidase, Cytosolic II Interaction Partners

Human 5'-Nucleotidase, Cytosolic II (NT5C2) interaction partners

  1. NT5C2 mutations seem to have a broad clinical spectrum and should be sought in patients manifesting either as uncomplicated or complicated spastic paraplegia

  2. Using data from a large-scale genome-wide association study of schizophrenia, study identified several potentially functional variants relating to miRNA function with our top finding being a schizophrenia protective allele that disrupts miR-206s binding to NT5C2 thus leading to increased expression of this gene.

  3. acute lymphoblastic leukemia-specific mutations affect regulation of cN-II

  4. this study implicates altered neural expression of BORCS7, AS3MT, and NT5C2 in susceptibility to schizophrenia arising from genetic variation at the chromosome 10q24 locus

  5. NT5C2 variant rs11191580 conferred susceptibility to schizophrenia and affected the clinical symptoms of schizophrenia in a South Chinese Han population.

  6. The aberrantly spliced NT5C2 showed substantial reduction in expression level in the in-vitro study, indicating marked instability of the mutant NT5C2 protein.

  7. Leukemia Relapse-Associated Mutation of NT5C2 Gene is Rare in de Novo Acute Leukemias and Solid Tumors.

  8. cN-II co-immunoprecipitated both with wild type Ipaf and its LRR domain after transfection with corresponding expression vectors, but not with Ipaf lacking the LRR domain.

  9. Data indicate that type II cytosolic 5'-nucleotidase (cN-II) exerts a role in nucleotide and drug metabolism and regulating cell survival.

  10. Four novel body mass index-associated loci near the KCNQ1(rs2237892), ALDH2/MYL2 (rs671, rs12229654), ITIH4 (rs2535633) and NT5C2 (rs11191580) genes are identified in East Asian-ancestry populations.

  11. These results suggest that mutations in NT5C2 are associated with the outgrowth of drug-resistant clones in acute lymphoblastic leukemia

  12. results highlight the prominent role of relapse-specific mutations in NT5C2 as a mechanism of resistance to 6-Mercaptopurine and a genetic driver of relapse in acute lymphoblastic leukemia

  13. analysis of Drosophila and human 7-methyl GMP-specific nucleotidases

  14. Polymorphisms in the CYP17A1 and NT5C2 genes influence a reduction in both visceral and subcutaneous fat mass in Japanese women.

  15. seven high-resolution structures of human cN-II, including a ligand-free form and complexes with various substrates and effectors, were presented.

  16. cN-II has a role in protecting against progression of non-small cell lung cancer

  17. the expression level of cN-II mRNA might be a prognostic factor of high-risk MDS.

  18. Data describe the crystal structure of human cytosolic 5'-nucleotidase II and discuss its allosteric regulation and substrate recognition.

  19. In leukoblasts from 82 patients with acute myeloid leukemia, various extent and frequency of differential allelic expression in the CDA, DCK, NT5C2, NT5C3, and TP53 genes was observed.

  20. The DCK/cN-II ratio was again proportional to ara-CTP production and to ara-C sensitivity.

Mouse (Murine) 5'-Nucleotidase, Cytosolic II (NT5C2) interaction partners

  1. The results on muscles from the NT5C knockout mice contradict previous findings where AMP levels and AMPK activity were shown to be modulated by NT5C enzymes.

Cow (Bovine) 5'-Nucleotidase, Cytosolic II (NT5C2) interaction partners

  1. mutated three residues that mediate interaction in the first activation site (R144, N154, I152) and three in the second (F127, M436 and H428), and found that ApA and ADP interact with the same site, but the sites for ATP and BPG remain uncertain

5'-Nucleotidase, Cytosolic II (NT5C2) Antigen Profile

Antigen Summary

This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides.

Gene names and symbols associated with NT5C2

  • 5'-nucleotidase, cytosolic II (NT5C2) antibody
  • 5'-nucleotidase, cytosolic II (nt5c2.L) antibody
  • 5'-nucleotidase, cytosolic II (nt5c2) antibody
  • 5'-nucleotidase, cytosolic IIa (nt5c2a) antibody
  • 5'-nucleotidase, cytosolic II (Nt5c2) antibody
  • 5'-nucleotidase, cytosolic II (surE2) antibody
  • 2010002I23Rik antibody
  • cN-II antibody
  • CnII antibody
  • ENSMUSG00000025039 antibody
  • Gm9751 antibody
  • Gmp antibody
  • Nt5b antibody
  • NT5C2 antibody
  • Pnt5 antibody
  • wu:fc36f11 antibody
  • wu:fc45b10 antibody

Protein level used designations for NT5C2

cytosolic 5'-nucleotidase II , cytosolic purine 5'-nucleotidase , 5'-nucleotidase, cytosolic II , fc36f11 , 5'-nucleotidase (purine), cytosolic type B , IMP-specific 5'-NT , purine 5' nucleotidase , 5'-nucleotidase cytosolic II , cytosolic IMP/GMP-specific 5'-nucleotidase , cytosolic purine 5'-nucleotidase-like

GENE ID SPECIES
477809 Canis lupus familiaris
444729 Xenopus laevis
548490 Xenopus (Silurana) tropicalis
714292 Macaca mulatta
324845 Danio rerio
22978 Homo sapiens
450706 Pan troglodytes
76952 Mus musculus
281951 Bos taurus
423871 Gallus gallus
100172749 Pongo abelii
5808749 Sorangium cellulosum So ce56
100363253 Rattus norvegicus
100402763 Callithrix jacchus
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