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The protein encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins.
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Mouse (Murine) Polyclonal ARFGAP3 Primary Antibody for ELISA, WB - ABIN257665
Liu, Zhang, Xing, Chen, He: Functional characterization of novel human ARFGAP3. in FEBS letters 2001
Human Polyclonal ARFGAP3 Primary Antibody for IP, WB - ABIN438757
Dembla, Wahl, Katiyar, Schmitz: ArfGAP3 is a component of the photoreceptor synaptic ribbon complex and forms an NAD(H)-regulated, redox-sensitive complex with RIBEYE that is important for endocytosis. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2014
Human Polyclonal ARFGAP3 Primary Antibody for WB - ABIN2477490
Unusi?: [Surgical method in interfascicular nerve transplantation]. in Chirurgia maxillofacialis & plastica 1977
Show all 2 Pubmed References
We suggest a model in which ArfGAP3 regulates Golgi association of GGA clathrin adaptors.
our results suggest that ARFGAP3 is a novel androgen-regulated gene that can promote prostate cancer cell proliferation and migration in collaboration with paxillin (show PXN Antibodies).
human ARFGAP2 (show arfgap2 Antibodies) and ARFGAP3 are associated with COP (show CARD16 Antibodies)-I-coated vesicles and function in COP (show CARD16 Antibodies) I traffic
Differential roles of ArfGAP1, ArfGAP2 (show arfgap2 Antibodies), and ArfGAP3 in COPI trafficking
ArfGAP1, ArfGAP2 (show arfgap2 Antibodies), and ArfGAP3 have overlapping roles in regulating COPI function in Golgi-to-ER retrograde transport.
ArfGAP3 interacts with RIBEYE (show CTBP2 Antibodies) in an NAD(H)-dependent manner.
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
ADP-ribosylation factor GTPase activating protein 1
, ADP-ribosylation factor GTPase-activating protein 3
, ARF GAP 3
, ADP-ribosylation factor GTPase activating protein 3
, ADP ribosylation factor GTPase activating protein 3 S homeolog