anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) Antibodies

Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. Additionally we are shipping ABCC1 Kits (37) and ABCC1 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCC1 4363 P33527
ABCC1 17250 O35379
ABCC1 24565 Q8CG09
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Top anti-ABCC1 Antibodies at antibodies-online.com

Showing 10 out of 133 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ABCC1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-MRP1 antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: CEM Cell Lysate Lane 3: A549 Cell Lysate Anti-MRP1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of MRP1 using anti-MRP1 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions. Lane 1: HELA whole cell lysates, Lane 2: A549 whole cell lysates.After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-MRP1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for MRP1 at approximately 220KD. The expected band size for MRP1 is at 220KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Goat Un-conjugated ELISA, WB EB08734 (0.05µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Cow Rabbit Un-conjugated WB Western blot analysis of MRP expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rat Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$544.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of ABCC1 antibody (C-term) (ABIN390525) in Ramos cell line lysates (35 µg/lane). ABCC1 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of NCI-H292 cells using ABCC1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$544.50
Details
Human Mouse Fluorescein FACS Detection of MRP1 in H69AR Human Cell Line by Flow Cytometry. H69AR human small cell lung cancer cell line was stained with Mouse Anti-Human MRP1 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$281.75
Details
Human Mouse PE FACS Detection of MRP1 in H69AR Human Cell Line by Flow Cytometry. H69AR human small cell lung cancer cell line was stained with Mouse Anti-Human MRP1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$351.90
Details

ABCC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ABCC1 Antibodies

  1. Human Polyclonal ABCC1 Primary Antibody for IHC (p), WB - ABIN3044230 : Wang, Zhao, Wu, He, Qu, Zhao, Zhao, Li, Wang: Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line. in Asian Pacific journal of cancer prevention : APJCP 2013 (PubMed)
    Show all 2 Pubmed References

  2. Monoclonal ABCC1 Primary Antibody for IF, WB - ABIN534097 : Chen, Yang, Li, Zhang: The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. in The Journal of biological chemistry 2006 (PubMed)

  3. Human Monoclonal ABCC1 Primary Antibody for FACS - ABIN4898743 : Takahashi, Shibata, Oba, Ishikawa, Yoshikawa, Tatsunami, Takahashi, Tampo: Multidrug-resistance-associated protein plays a protective role in menadione-induced oxidative stress in endothelial cells. in Life sciences 2009 (PubMed)

  4. Human Monoclonal ABCC1 Primary Antibody for FACS - ABIN4898742 : Keshet, Goldstein, Itzhaki, Cesarkas, Shenhav, Yakirevitch, Treves, Schachter, Amariglio, Rechavi: MDR1 expression identifies human melanoma stem cells. in Biochemical and biophysical research communications 2008 (PubMed)

  5. Human Monoclonal ABCC1 Primary Antibody for CyTOF, FACS - ABIN4900819 : Fiskus, Rao, Fernandez, Herger, Yang, Chen, Kolhe, Mandawat, Wang, Joshi, Eaton, Lee, Atadja, Peiper, Bhalla: Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells. in Blood 2008 (PubMed)

  6. Human Polyclonal ABCC1 Primary Antibody for ELISA, IHC - ABIN6266183 : Zhou, Lin, Zhang, Zhang, Zhang, Zhang, Xie, Ren: miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression. in Cell proliferation 2017 (PubMed)

More Antibodies against ABCC1 Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. Peripheral blood MRP1 (show MDM4 Antibodies) expression is increased in patients with refractory epilepsy

  2. Due to the downregulation of MDR1 (show TBC1D9 Antibodies) and MRP1 (show MDM4 Antibodies), the intracellular accumulation of ADM (show ADM Antibodies) was increased in the transfected cells compared with that in the parental K562/ADM (show ADM Antibodies) cells..Our research revealed that protein expression of the ERK (show EPHB2 Antibodies) signaling pathway was inhibited by downregulating TRIB2 (show TRIB2 Antibodies), indicating that the ERK (show EPHB2 Antibodies) pathway was involved in cell drug resistance and proliferation.

  3. This study provides a brand new evidence that GOLPH3 (show GOLPH3 Antibodies) promotes glioma cell proliferation by facilitating Wls (show WLS Antibodies) recycling and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  4. icaritin (ICT) decreased the mRNA and protein levels of multidrug resistance-associated protein 1 (MRP1) in MG-63 doxorubicin-resistant (MG-63/DOX) cells.

  5. Enhanced BRAF (show BRAF Antibodies)-mediated NRF2 (show GABPA Antibodies) gene transcription and Histone Acetyltransferases-mediated NRF2 (show GABPA Antibodies) protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II (show TOP2 Antibodies) poison-resistant cancer cells.

  6. Pomolic acid also down-modulated the activity of the multidrug resistance associated protein 1 (MRP1) and inhibited migration of Glioblastoma (GBM) cells. These results show that PA acts on several pathways of GBM drug resistance and therefore may be of potential interest for the treatment of this tumor

  7. Our data present for the very first time the high negative correlation between MRP1 (show MDM4 Antibodies) protein expression in LSC (show ARHGEF1 Antibodies) and AML (show RUNX1 Antibodies) patients' remission. It does strongly suggest that MRP1 (show MDM4 Antibodies) expression in LSC (show ARHGEF1 Antibodies) is an adverse prognostic marker in patients with de novo AML (show RUNX1 Antibodies).

  8. These data showed that Wls (show WLS Antibodies) was differentially expressed in HCC (show FAM126A Antibodies). Statistical analysis results suggest that Wls (show WLS Antibodies) expression might increase as HCC (show FAM126A Antibodies) progresses.

  9. No significant correlation was observed between rs504348 genotypes and cystic fibrosis (show S100A8 Antibodies) severity. A significantly higher expression of ABCC1 mRNA was induced by CF plasma compared to healthy control plasma.

  10. MRP1 (show MDM4 Antibodies) is regulated by CLIC1 (show CLIC1 Antibodies), leading to CLIC1 (show CLIC1 Antibodies)-mediated development of chemoresistance in choriocarcinoma cells.

Cow (Bovine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. Using electron cryomicroscopy, authors determined the molecular structures of bovine MRP1 in two conformations: an apo (show C9orf3 Antibodies) form at 3.5 A without any added substrate and a complex form at 3.3 A with one of its physiological substrates, leukotriene C4; structures show that by forming a single bipartite binding site, MRP1 can recognize a of substrates with different chemical structures.

  2. P-gp (show ABCB4 Antibodies), Bcrp and Mrp1 are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. Mrp1 protects cardiac myocytes and fibroblasts against doxorubicin-induced toxicity, potentially by regulating extracellular redox states.

  2. Loss of ABCC1 expression is associated with neonatal hyperbilirubinemia.

  3. Data, including data from studies in knockout mice, suggest that Mrp1 is involved in development of vascular endothelial dysfunction in diabetic angiopathy; Mrp1 appears to be required for oxidative stress in endothelial cells due to hyperglycemia.

  4. Oxidant-enriched Tumorigenic Endothelial Cells (EOMA) cells survive a heavy oxidant burden by rapid efflux of GSSG, which is lethal if trapped within the cell. A hyperactive MRP-1 system for GSSG efflux acts as a critical survival factor for these cells, making it a potential target for EOMA therapeutics.

  5. P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier

  6. Lentivirus-based RNAi stably knocks down the expression of the Mrp1 gene in the established TM4 (show TPM4 Antibodies) sertoli cell line.

  7. neprilysin (show MME Antibodies) x ABCC1 double-deficient mice present a new model for early effects of amyloid-beta-related mild cognitive impairment that allows investigations without artificial overexpression of inherited Alzheimer's disease genes

  8. Expression of apoA-I (show APOA1 Antibodies) or ABCA1 (show ABCA1 Antibodies) can reduce steatosis by decreasing lipid storage in hepatocytes through lipid transport and may also reduce endoplasmic reticulum stress, further lessening hepatic steatosis

  9. Loss of Mrp1 coupled with reductions in steroid hormone levels leads to alterations in extrahepatic phase I, phase II and phase III metabolizing enzymes in a tissue-specific manner.

  10. Cd or H(2)O(2) exposure increased the expression of key transport genes, Mrp1 and Mrp2 (show ABCC2 Antibodies), in WT cells but not in metallothionein (show MT Antibodies)-null cells.

Rabbit ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. MRP1 appears to be primarily localized in the basolateral membrane of conjunctival epithelial cells and functions in the efflux of certain organic anions and inflammatory factors

ABCC1 Antigen Profile

Protein Summary

Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).

Gene names and symbols associated with ABCC1

  • ATP binding cassette subfamily C member 1 (ABCC1) antibody
  • wntless Wnt ligand secretion mediator (WLS) antibody
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1) antibody
  • ATP binding cassette subfamily C member 1 (Abcc1) antibody
  • multidrug resistance-associated protein 1 (LOC100152428) antibody
  • multidrug resistance-associated protein 1 (LOC100346553) antibody
  • ABC29 antibody
  • ABCC antibody
  • Abcc1a antibody
  • Abcc1b antibody
  • ABCC13 antibody
  • Avcc1a antibody
  • C1orf139 antibody
  • EVI antibody
  • GPR177 antibody
  • GS-X antibody
  • Mdrap antibody
  • mig-14 antibody
  • Mrp antibody
  • Mrp1 antibody

Protein level used designations for ABCC1

ATP-binding cassette transporter variant ABCC1delta-ex13 , ATP-binding cassette transporter variant ABCC1delta-ex13&14 , ATP-binding cassette transporter variant ABCC1delta-ex25 , ATP-binding cassette transporter variant ABCC1delta-ex25&26 , LTC4 transporter , leukotriene C(4) transporter , multidrug resistance-associated protein 1 , G protein-coupled receptor 177 , integral membrane protein GPR177 , protein evenness interrupted homolog , protein wntless homolog , putative NF-kappa-B-activating protein 373 , putative NFkB activating protein 373 , ATP-binding cassette sub-family C member 1 , multidrug resistance protein 1 , ATP-binding cassette, sub-family C (CFTR/MRP), member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1b , multiple drug resistance-associated protein , ATP-binding cassette sub-family C ( CFTR/MRP) member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1 , ATP-binding cassette superfamily member C1 , ATP-binding cassette transporter sub-family C member 1 , ATP-binding cassette, sub-family C, member 1 , multiple drug resistance protein 1 , ATP-binding cassette, sub-family C (CFTR/MRP), member 13

GENE ID SPECIES
4363 Homo sapiens
79971 Homo sapiens
281588 Bos taurus
395416 Gallus gallus
403453 Canis lupus familiaris
17250 Mus musculus
24565 Rattus norvegicus
100734674 Cavia porcellus
733619 Sus scrofa
791240 Equus caballus
100345841 Oryctolagus cuniculus
100152428 Sus scrofa
100346553 Oryctolagus cuniculus
Selected quality suppliers for anti-ABCC1 (ABCC1) Antibodies
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