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The protein encoded by ABCF2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family F (GCN20), Member 2 Proteins (5) and many more products for this protein.
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The NRF2-overexpressing cell line, containing high levels of ABCF2, was more resistant to cisplatin-induced apoptosis compared to its control ovarian cancer cell line; whereas the NRF2 knockdown cell line with low levels of ABCF2, was more sensitive to cisplatin treatment than its control cell line.
Overexpression of ABCF2 suppressed RVD.
ABCF2 may have a role in progression of clear cell ovarian adenocarcinomas
Data suggest that ABCF2 protein may be a candidate marker for clear cell adenocarcinomas of the ovary and the uterine corpus and may be important for the pathogenesis of these diseases.
Among cervical cancer cases, 149 (55.8%) expressed ABCF2. The overall survival was longer in ABCF2-negative than ABCF2-positive cases
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.
ABC transporter, class F family member (abcf-2)
, ATP-binding cassette sub-family F member 2
, ATP-binding cassette, sub-family F (GCN20), member 2
, ATP-binding cassette, sub-family F, member 2
, ATP-binding cassette sub-family F member 2-like
, ABC-type transport protein
, iron-inhibited ABC transporter 2
, developmentally regulated repeat element-containing transcript 3