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The protein encoded by SCARF1 is a scavenger receptor that is expressed in endothelial cells.
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Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 (show TLR3 ELISA Kits) activation in human monocytes
These studies in addition to our earlier findings showed SREC-I to play a primary role in chaperone-associated antigen uptake both through cross priming of MHC class I molecules and entry into the class II pathway.
In several assay systems this type F-scavenger receptor, termed SREC-I, bound to cell wall techoic acid in a charge dependent manner and mediated adhesion to nasal epithelial cells in vitro.
GP2 (show GP2 ELISA Kits) is a binding partner of the scavenger receptor expressed on endothelial cells I (SREC-I) but not of SR-AI (show MSR1 ELISA Kits) and SR-BI (show SCARB1 ELISA Kits). Dendritic cells express SREC-I and also bind and internalize GP2 (show GP2 ELISA Kits).
SRECI binds to SRECII (show SCARF2 ELISA Kits) and has a similar tissue distribution pattern
SREC-I became associated with TLR4 (show TLR4 ELISA Kits) on binding bacterial lipopolysaccharides in RAW 264.7.
The scavenger receptor SCARF1 (show SCARF2 ELISA Kits) mediates the clearance of apoptotic cells and prevents autoimmunity.
SREC-I mediated internalization of Hsp90 (show HSP90 ELISA Kits)-ovalbumin (show OVA ELISA Kits) polypeptide complexes through an endocytic pathway known as the glycosylphosphatidylinositol-anchored protein-enriched early endosomal compartment to recycling endosomes.
interaction of SREC-I and advillin are involved in the development of dorsal root ganglion neurons by inducing the described morphological changes.
Our system may be useful for the elucidation of the mechanism of morphological maturation of neuronal cells such as dorsal root ganglion neurons that express SREC-I during early development.
CED-1/SCARF1 (show SCARF2 ELISA Kits) and C03F11.3/CD36 (show CD36 ELISA Kits) are beta-glucan binding receptors and define an evolutionarily conserved pathway for the innate sensing of fungal pathogens.
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants.
acetyl LDL receptor
, scavenger receptor class F member 1
, scavenger receptor expressed by endothelial cells 1
, scavenger receptor expressed by endothelial cells 1 protein
, endothelial cells scavenger receptor