anti-Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) Antibodies

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Additionally we are shipping ACTG2 Kits (10) and ACTG2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACTG2 72 P63267
ACTG2 11468 P63268
ACTG2 25365 P63269
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Top anti-ACTG2 Antibodies at

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ACTG2 Antibody Titration: 0.25 ug/ml Positive Control: Fetal Lung 100 μL 2 to 3 Days
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COLO205 cells, using Actin-gamma2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Actin-gamma2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Chicken Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Alpha-actin-3 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Alpha-actin-3 staining in human muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Lung Tissue; Lane2: Porcine Stomach Tissue; Lane3: Rat Stomach Tissue. 100 μg 15 to 18 Days
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 to 14 Days
Bat Rabbit Un-conjugated IHC, IHC (p), WB Anti-ACTG2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other for ... 100 μL 11 to 14 Days
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6266836 at 1/100 staining human brain tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis on COLO205 cell lysate using Actin-gamma2 Antibody,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 to 12 Days
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis in CEM cell line lysates (35ug/lane). ACTG2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate cancinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 to 13 Days
Human Rabbit Un-conjugated IF/ICC, IHC, IP, WB Western blot analysis of (1) Human Lung Tissue, (2) Porcine Stomach Tissue and (3) Rat Stomach Tissue. Western blot analysis of recombinant Human ACTg2. 100 μg 31 to 36 Days

Top referenced anti-ACTG2 Antibodies

  1. Human Polyclonal ACTG2 Primary Antibody for IHC, ELISA - ABIN1533207 : Morioka, Takano-Ohmuro: Localizations of γ-Actins in Skin, Hair, Vibrissa, Arrector Pili Muscle and Other Hair Appendages of Developing Rats. in Acta histochemica et cytochemica 2016 (PubMed)

More Antibodies against ACTG2 Interaction Partners

Human Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) interaction partners

  1. mutations represent a significant underlying cause of primary chronic intestinal pseudo-obstruction with visceral myopathy and associated phenotypes in Australasian patients.

  2. fetus with intestinal pseudo-obstruction heterozygous for p.R63G pathogenic variant (NM_001615.3 c.187C>G; rs864309491) in exon 3

  3. Whole exome and Sanger sequencing revealed a pathogenic variant in the ACTG2 gene in 4 out of 28 probands with chronic intestinal pseudo-obstruction and megacystis. Moreover, a mutational hotspot in the ACTG2 gene was recognized. Genetic heterogeneity is evident.

  4. R257 variant in the ACTG2 appear to be more frequent in populations of Asian ancestry; mutation of this locus could cause alterations of the intestinal and bladder smooth muscle filaments.

  5. ACTG2 boosts the metastatic potential of hepatocellular carcinoma in a Notch1-dependent manner.

  6. Missense variants in ACTG2 were identified in the patients with either megacystis-microcolon-intestinal hypoperistalsis syndrome or intestinal pseudo-obstruction.

  7. A heterozygous missense variant in ACTG2 was identified that impaired actin polymerization in sporadic Megacystis microcolon intestinal hypoperistalsis syndrome.

  8. ACTG2 is expressed in a fraction of small intestinal neuroendocrine tumors, can inhibit cell growth in vitro, and is positively regulated by miR-145.

  9. Mutations within ACTG2 are associated with fetal megacystis in microcolon intestinal hypoperistalsis syndrome.

  10. Phenotypic spectrum of ACTG2 missense variants involved severe pathology in multiple smooth muscle-dependent organs including the biliary tract and the uterus in the family with visceral myopathy.

  11. gammaSMA expression in hepatocellular carcinoma is strongly correlated with the EMT process, HCC aggressiveness and the identification of cancer stem cells

  12. ACTG2 encodes g2 enteric actin and is the first gene to be clearly associated with Megacystis-microcolon-intestinal hypoperistalsis syndrome, suggesting an important role for contractile proteins in enteric smooth muscle disease.

  13. Two novel mutations in the ACTG2 gene, p.R178L and p.R178C, have been identified in two unrelated children with congenital distended bladder, microcolon, and intestinal hypoperistalsis (MMIHS).

  14. The R148S variant in ACTG2 as a cause of autosomal dominant familial visceral myopathy in one family.

  15. NOX4 and ROS have a role in myofibroblast differentiation and collagen and alpha-actin production of TGF- beta1-induced nasal polyp-derived fibroblasts.

  16. SMGA gene activity in prostate epithelia is due, in part, to the androgen-dependent expression of Nkx 3.1

  17. RNA polymerase II accumulates in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes.

  18. It was suggested that peritubular alphaSMA-positive myofibroblastic cells, in collaboration with interstitial macrophages, contribute to the progression of interstitial fibrosis in diabetic nephropathy.

  19. TNF-alpha suppresses TGF-beta1-induced myofibroblast (fibroproliferative) phenotypic genes, for example, alpha-SMA, collagen type 1A, and fibronectin at the mRNA level.

  20. The insertion-deletion polymorphism in intron 1 of the gamma 2 actin gene is unlikely to play any significant role in obstetric cholestasis or preeclampsia in patients from eastern Finland.

Mouse (Murine) Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) interaction partners

  1. ACTG2 boosts the metastatic potential of hepatocellular carcinoma in a Notch1-dependent manner.

  2. MYOCD can discriminate among several juxtaposed CArG elements, presumably through its novel partnership with NKX3.1, to optimally transactivate the human ACTG2 promoter

ACTG2 Antigen Profile

Protein Summary

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2\; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.

Gene names and symbols associated with ACTG2

  • actin, gamma 2, smooth muscle, enteric (ACTG2) antibody
  • actin, gamma 2, smooth muscle, enteric (Actg2) antibody
  • ACT antibody
  • Act-4 antibody
  • Act4 antibody
  • ACTA3 antibody
  • ACTE antibody
  • ACTG2 antibody
  • ACTGE antibody
  • ACTL3 antibody
  • ACTSG antibody
  • GAMMA-ACTIN antibody
  • SMGA antibody

Protein level used designations for ACTG2

actin, gamma 2, smooth muscle, enteric , actin, gamma-enteric smooth muscle , alpha-actin-3 , gamma-2-actin , smooth muscle gamma-actin , actin-like protein , alpha-actin 3 , smooth muscle gamma actin , actin, gamma-enteric smooth muscle-like , actin, gamma 2 propeptide-like , alpha-smooth muscle actin , gamma-enteric smooth muscle actin

739500 Pan troglodytes
475792 Canis lupus familiaris
100057561 Equus caballus
707447 Macaca mulatta
396084 Gallus gallus
281595 Bos taurus
72 Homo sapiens
11468 Mus musculus
100404219 Callithrix jacchus
100350318 Oryctolagus cuniculus
25365 Rattus norvegicus
100581173 Nomascus leucogenys
100716255 Cavia porcellus
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