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Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Additionally we are shipping ACTG2 Kits (33) and ACTG2 Proteins (9) and many more products for this protein.
Showing 10 out of 178 products:
Human Polyclonal ACTG2 Primary Antibody for ICC, IF - ABIN153416
Jeyasuria, Wetzel, Bradley, Subedi, Condon: Progesterone-regulated caspase 3 action in the mouse may play a role in uterine quiescence during pregnancy through fragmentation of uterine myocyte contractile proteins. in Biology of reproduction 2009
Show all 31 Pubmed References
Human Monoclonal ACTG2 Primary Antibody for IEM, ICC - ABIN335372
Chaponnier, Goethals, Janmey, Gabbiani, Gabbiani, Vandekerckhove: The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo. in The Journal of cell biology 1995
Show all 14 Pubmed References
Human Polyclonal ACTG2 Primary Antibody for ELISA, IHC - ABIN268804
Austin, Sens, Combs: Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Show all 13 Pubmed References
Human Polyclonal ACTG2 Primary Antibody for ICC, IF - ABIN407579
Lehtonen, Sipponen, Tojkander, Karikoski, Järvinen, Laing, Lappalainen, Aaltonen, Tuupanen: Segregation of a missense variant in enteric smooth muscle actin γ-2 with autosomal dominant familial visceral myopathy. in Gastroenterology 2012
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Human Polyclonal ACTG2 Primary Antibody for IHC, IHC (fro) - ABIN440939
Gai, Chu, Xu, Song, Sun, Kullak-Ublick: Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage. in Scientific reports 1970
Cat (Feline) Polyclonal ACTG2 Primary Antibody for IHC (p), IHC - ABIN269603
Dafni, Burghardt, Majumdar, Navone, Ronen: Vascular patterning and permeability in prostate cancer models with differing osteogenic properties. in NMR in biomedicine 2012
Baboon Monoclonal ACTG2 Primary Antibody for ELISA, FACS - ABIN4280072
El Agha, Moiseenko, Kheirollahi, De Langhe, Crnkovic, Kwapiszewska, Kosanovic, Schwind, Schermuly, Henneke, MacKenzie, Quantius, Herold, Ntokou, Ahlbrecht, Morty, Günther, Seeger, Bellusci: Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis. in Cell stem cell 2016
Human Monoclonal ACTG2 Primary Antibody for ELISA, FACS - ABIN4280057
Ghatak, Markwald, Hascall, Dowling, Lottes, Baatz, Beeson, Beeson, Perrella, Thannickal, Misra: Transforming growth factor β1 (TGFβ1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts. in The Journal of biological chemistry 2017
TnT has a previously unrecognized role in forming the inactive state of regulated actin.
The terminal pointed end subunit is tilted (show OTOP1 Antibodies) towards the penultimate subunit, allowing specific and extra loop-to-loop inter-strand contacts between the two end subunits, which is not possible in other parts of the filament.
There was no significant change in the expression of TGF-beta(2 (show TGFB2 Antibodies)) and alpha-SMA (show SMN1 Antibodies) after laser-assisted intrastromal scanning.
The arrangement of actin subunits in an actin dimer assembled by tandem W domains resembles that of a long-pitch helix of the actin filament.
The distribution of laminin and alphaSMA (show ACTA2 Antibodies) in the testis and epididymis might point out to their roles in the male reproduction.
R257 variant in the ACTG2 appear to be more frequent in populations of Asian ancestry; mutation of this locus could cause alterations of the intestinal and bladder smooth muscle filaments.
ACTG2 boosts the metastatic potential of hepatocellular carcinoma in a Notch1 (show NOTCH1 Antibodies)-dependent manner.
Missense variants in ACTG2 were identified in the patients with either megacystis-microcolon-intestinal hypoperistalsis syndrome or intestinal pseudo-obstruction.
A heterozygous missense variant in ACTG2 was identified that impaired actin polymerization in sporadic Megacystis microcolon intestinal hypoperistalsis syndrome.
ACTG2 is expressed in a fraction of small intestinal neuroendocrine tumors, can inhibit cell growth in vitro, and is positively regulated by miR (show MLXIP Antibodies)-145.
Mutations within ACTG2 are associated with fetal megacystis in microcolon intestinal hypoperistalsis syndrome.
Phenotypic spectrum of ACTG2 missense variants involved severe pathology in multiple smooth muscle-dependent organs including the biliary tract and the uterus in the family with visceral myopathy.
gammaSMA expression in hepatocellular carcinoma is strongly correlated with the EMT (show ITK Antibodies) process, HCC (show FAM126A Antibodies) aggressiveness and the identification of cancer stem cells
ACTG2 encodes g2 enteric actin and is the first gene to be clearly associated with Megacystis-microcolon-intestinal hypoperistalsis syndrome, suggesting an important role for contractile proteins in enteric smooth muscle disease.
Two novel mutations in the ACTG2 gene, p.R178L and p.R178C, have been identified in two unrelated children with congenital distended bladder, microcolon, and intestinal hypoperistalsis (MMIHS).
MYOCD (show MYOCD Antibodies) can discriminate among several juxtaposed CArG elements, presumably through its novel partnership with NKX3.1 (show NKX3-1 Antibodies), to optimally transactivate the human ACTG2 promoter
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2\; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.
actin, gamma 2, smooth muscle, enteric
, actin, gamma-enteric smooth muscle-like
, actin, gamma 2 propeptide-like
, actin, aortic smooth muscle
, alpha-smooth muscle actin
, actin, gamma-enteric smooth muscle
, gamma-enteric smooth muscle actin
, smooth muscle gamma-actin
, actin-like protein
, alpha-actin 3
, smooth muscle gamma actin