anti-Adaptor-Related Protein Complex 1, mu 1 Subunit (AP1M1) Antibodies

The protein encoded by AP1M1 is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. Additionally we are shipping AP1M1 Kits (21) and AP1M1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AP1M1 11767 P35585
AP1M1 8907 Q9BXS5
AP1M1 306332 Q32Q06
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Top anti-AP1M1 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB AP1M1 Antibody (Center) western blot analysis in mouse heart tissue lysates (35µg/lane).This demonstrates the AP1M1 antibody detected the AP1M1 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Mouse Rabbit Un-conjugated WB AP1M1 Antibody (Center) (ABIN655298) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the AP1M1 antibody detected the AP1M1 protein (arrow). Overlay histogram showing U-251 MG cells stained with ABIN2844885(green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (ABIN2844885, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(1583138) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG1 (1μg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. Dilution: 1:25 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB AP1M1 Antibody (Center) (ABIN655975) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. Anti-AP1M1 Antibody (Center) at 1:2000 dilution + Human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 49 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts from various samples, using AP1M1 antibody. Lane 1: rat heart treated with blocking peptide. Lane 2: Rat heart; Lane 3: Mouse brain; Lane 4: Hepg2; Lane 5: B16F10; Western blot analysis of extracts of Hacat cells, using AP1M1 antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, WB   0.4 mL 4 to 8 Days
$522.50
Details
Mouse Rabbit Un-conjugated WB Western blot analysis in mouse heart tissue lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of lysates from A375 cell line and rat testis tissue lysate(from left to right), using AP1M1 Antibody at 1:1000 at each lane. AP1M1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using AP1M1 antibody. Western blot analysis of extracts of various cell lines, using AP1M1 antibody (ABIN4902918) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. 100 μL 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated ELISA, WB AP1M1 polyclonal antibody (A01), Lot # 060717JCS1 Western Blot analysis of AP1M1 expression in U-2 OS . Western Blot detection against Immunogen (34.25 KDa) . 50 μL 11 to 12 Days
$305.71
Details

Top referenced anti-AP1M1 Antibodies

  1. Human Polyclonal AP1M1 Primary Antibody for ELISA, WB - ABIN522393 : Sawasdee, Junking, Ngaojanlar, Sukomon, Ungsupravate, Limjindaporn, Akkarapatumwong, Noisakran, Yenchitsomanus: Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 ?1A (AP-1 mu1A). in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal AP1M1 Primary Antibody for EIA, WB - ABIN5556187 : Carnevale, Raparelli, Nocella, Bartimoccia, Novo, Severino, De Falco, Cammisotto, Pasquale, Crescioli, Scavalli, Riggio, Basili, Violi: Gut-derived endotoxin stimulates factor VIII secretion from endothelial cells. Implications for hypercoagulability in cirrhosis. in Journal of hepatology 2018 (PubMed)

More Antibodies against AP1M1 Interaction Partners

Mouse (Murine) Adaptor-Related Protein Complex 1, mu 1 Subunit (AP1M1) interaction partners

  1. L-selectin is transported constitutively by the AP-1 complex, leading to the formation of a trans-Golgi network reserve pool; phosphorylation of the L-selectin tail blocks AP-1-dependent retrograde transport of L-selectin

  2. In mu1A-adaptin-deficient fibroblasts, MPR300-mediated endocytosis is markedly enhanced by a mechanism not associated with increased steady-state concentration of receptors at the plasma membrane, but with an increased internalization rate of MPR300.

Human Adaptor-Related Protein Complex 1, mu 1 Subunit (AP1M1) interaction partners

  1. It has been shown that the cytoplasmic domains of furin bind the mu subunits of AP-1 and AP-2 in a phosphorylation-dependent manner.

  2. Here, the authors demonstrate that dileucine motifs in the hepatitis C virus NS2 protein mediate AP-1A, AP-1B, and AP-4 binding and cell-free virus release. Moreover, they reveal that AP-4, an adaptor not previously implicated in viral infections, mediates cell-to-cell spread and hepatitis C virus trafficking.

  3. found 31 ORF9p interaction partners, among which was AP1M1, the mu subunit of the adaptor protein complex 1 (AP-1). AP-1 is a heterotetramer involved in intracellular vesicle-mediated transport and regulates the shuttling of cargo proteins between endosomes and the trans-Golgi network via clathrin-coated vesicles.

  4. Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. The basic patch on micro1 that interacts with the Nef acidic cluster also contributes to the binding of endogenous acidic cluster proteins.

  5. CNNM4 is sorted to the basolateral membrane by the complementary function of AP-1A and AP-1B

  6. Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.

  7. IRS-1 associates with mu1A of the ubiquitously expressed AP-1 complex through three protein interaction motifs.

  8. Mu1A binding to the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes.

  9. AP-1 mu1A is involved in the kAE1 trafficking of kidney alpha-intercalated cells

  10. These data identify the micro subunit of AP-1 (micro1) as the key target of the MHC-I CD/Nef complex, and they indicate that both Y320 in the MHC-I CD and E62-65 in Nef interact directly with micro1.

AP1M1 Antigen Profile

Protein Summary

The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Gene names and symbols associated with AP1M1

  • adaptor-related protein complex AP-1, mu subunit 1 (Ap1m1) antibody
  • adaptor related protein complex 1 mu 1 subunit (AP1M1) antibody
  • adaptor-related protein complex 1, mu 1 subunit (Ap1m1) antibody
  • adaptor related protein complex 1 mu 1 subunit (Ap1m1) antibody
  • adaptor related protein complex 1 mu 1 subunit S homeolog (ap1m1.S) antibody
  • AA408894 antibody
  • Adtm1A antibody
  • ap1m1 antibody
  • AP47 antibody
  • CLAPM2 antibody
  • CLTNM antibody
  • MU-1A antibody
  • Mu1a antibody
  • [m]1A antibody

Protein level used designations for AP1M1

AP-1 complex subunit mu-1 , AP-mu chain family member mu1A , adaptor protein complex AP-1 mu-1 subunit , adaptor-related protein complex 1 mu-1 subunit , clathrin assembly protein complex 1 medium chain 1 , clathrin coat assembly protein AP47 , clathrin coat-associated protein AP47 , golgi adaptor HA1/AP1 adaptin mu-1 subunit , mu-adaptin 1 , mu1A-adaptin , HA1 47 kDa subunit , clathrin adaptor protein AP47 , clathrin assembly protein complex 1, medium chain , clathrin assembly protein complex AP1, mu subunit , golgi adaptor AP-1 47 kDa protein , adaptor-related protein complex AP-1, mu subunit 1 , adaptor related protein complex 1 mu 1 subunit S homeolog , adaptor-related protein complex 1, mu 1 subunit

GENE ID SPECIES
11767 Mus musculus
8907 Homo sapiens
306332 Rattus norvegicus
504310 Bos taurus
100729705 Cavia porcellus
420149 Gallus gallus
734499 Xenopus laevis
609840 Canis lupus familiaris
101685123 Mustela putorius furo
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