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The protein encoded by AP1M1 is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. Additionally we are shipping AP1M1 Kits (20) and AP1M1 Proteins (5) and many more products for this protein.
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Human Polyclonal AP1M1 Primary Antibody for ELISA, WB - ABIN522393
Sawasdee, Junking, Ngaojanlar, Sukomon, Ungsupravate, Limjindaporn, Akkarapatumwong, Noisakran, Yenchitsomanus: Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 ?1A (AP-1 mu1A). in Biochemical and biophysical research communications 2010
Show all 2 Pubmed References
Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. The basic patch on micro1 that interacts with the Nef acidic cluster also contributes to the binding of endogenous acidic cluster proteins.
CNNM4 (show CNNM4 Antibodies) is sorted to the basolateral membrane by the complementary function of AP-1A and AP-1B
Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.
IRS-1 (show IRS1 Antibodies) associates with mu1A of the ubiquitously expressed AP-1 (show FOSB Antibodies) complex through three protein interaction motifs.
Mu1A binding to the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes.
AP-1 (show FOSB Antibodies) mu1A is involved in the kAE1 (show OSGEP Antibodies) trafficking of kidney alpha-intercalated cells
These data identify the micro subunit of AP-1 (micro1) as the key target of the MHC-I CD/Nef complex, and they indicate that both Y320 in the MHC-I CD and E62-65 in Nef interact directly with micro1.
L-selectin (show SELL Antibodies) is transported constitutively by the AP-1 (show JUN Antibodies) complex, leading to the formation of a trans-Golgi network reserve pool; phosphorylation of the L-selectin (show SELL Antibodies) tail blocks AP-1 (show JUN Antibodies)-dependent retrograde transport of L-selectin (show SELL Antibodies)
In mu1A-adaptin-deficient fibroblasts, MPR300 (show IGF2R Antibodies)-mediated endocytosis is markedly enhanced by a mechanism not associated with increased steady-state concentration of receptors at the plasma membrane, but with an increased internalization rate of MPR300 (show IGF2R Antibodies).
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
adaptor-related protein complex 1, mu 1 subunit
, AP-1 complex subunit mu-1
, AP-mu chain family member mu1A
, HA1 47 kDa subunit
, adaptor protein complex AP-1 mu-1 subunit
, adaptor-related protein complex 1 mu-1 subunit
, clathrin adaptor protein AP47
, clathrin assembly protein complex 1 medium chain 1
, clathrin assembly protein complex 1, medium chain
, clathrin assembly protein complex AP1, mu subunit
, clathrin coat assembly protein AP47
, clathrin coat-associated protein AP47
, golgi adaptor AP-1 47 kDa protein
, golgi adaptor HA1/AP1 adaptin mu-1 subunit
, mu-adaptin 1
, adaptor-related protein complex AP-1, mu subunit 1