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anti-Aminopeptidase Puromycin Sensitive (NPEPPS) Antibodies

NPEPPS encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. Additionally we are shipping Aminopeptidase Puromycin Sensitive Kits (11) and Aminopeptidase Puromycin Sensitive Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPEPPS 9520 P55786
NPEPPS 19155 Q11011
NPEPPS 50558  
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Top anti-Aminopeptidase Puromycin Sensitive Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN238593 (0.3µg/ml) staining of Human Brain (Cerebral Cortex) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Cow Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p), WB Anti-NPEPPS antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml. 100 μL 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PSA antibody (C-term) in MCF-7 cell line lysates (35ug/lane). PSA (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human PANC1 cell lysate; Primary Ab: 1µg/ml Rabbit Anti-Human PSA Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Porcine Brain Tissue; Lane2: Human Lung Tissue. 100 μg 15 to 18 Days
$350.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Serum; Primary Ab: 1µg/ml Rabbit Anti-Mouse PSA Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 15 to 18 Days
$360.00
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Mouse Un-conjugated DB   50 μg 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$390.50
Details

Top referenced anti-Aminopeptidase Puromycin Sensitive Antibodies

  1. Human Polyclonal NPEPPS Primary Antibody for ELISA, WB - ABIN548215 : Karsten, Sang, Gehman, Chatterjee, Liu, Lawless, Sengupta, Berry, Pomakian, Oh, Schulz, Hui, Wiedau-Pazos, Vinters, Binder, Geschwind, Jackson: A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. in Neuron 2006 (PubMed)

More Antibodies against Aminopeptidase Puromycin Sensitive Interaction Partners

Fruit Fly (Drosophila melanogaster) Aminopeptidase Puromycin Sensitive (NPEPPS) interaction partners

  1. findings show that by promoting autophagic protein clearance, PSA helps protect against accumulation of aggregation-prone proteins and proteotoxicity

Zebrafish Aminopeptidase Puromycin Sensitive (NPEPPS) interaction partners

  1. the purification and characterization of a puromycin-sensitive aminopeptidase from zebrafish

Human Aminopeptidase Puromycin Sensitive (NPEPPS) interaction partners

  1. cytosolic peptidases(puromycin-sensitive aminopeptidase (PSA), aminopeptidase B (APB) and pyroglutamyl-peptidase I (PGI) ) may be involved in colorectal carcinogenesis

  2. Studies indicate the critical role of M1 aminopeptidases ERAP1, ERAP2 and NPEPPS in immune-mediated diseases.

  3. MiR-614 inhibited cell invasion and proliferationa targeting PSA in lung cancer cells, PGCL3

  4. Elevation of NPEPPS activity blocks accumulation of hyperphosphorylated TAU protein and slows down the progression of Alzheimer's disease.

  5. findings show that by promoting autophagic protein clearance, PSA helps protect against accumulation of aggregation-prone proteins and proteotoxicity

  6. attenuated proteolysis of FTDP-17 mutant tau may be explained by increased phosphorylation levels, resulting in resistance to proteolysis.

  7. ApPS Y394F exhibited a 3.3-fold lower affinity for RB-3014, a transition state inhibitor, indicating that Tyr394 is involved in transition state stabilization

  8. PSA gene was downregulated in PC-3 cells that were treated with CoCl(2). PSA is involved in the proliferation, migration, and invasion of PC-3 cells, which are important determinants of metastasis, via a mechanism that involves MMP-9 modulation.

Mouse (Murine) Aminopeptidase Puromycin Sensitive (NPEPPS) interaction partners

  1. Nucleocytoplasmic transfer of cyclin dependent kinase 5 and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum

  2. findings show that by promoting autophagic protein clearance, PSA helps protect against accumulation of aggregation-prone proteins and proteotoxicity

  3. These data indicate that PSA may play a role in limiting MHC class I Ag presentation in dendritic cells in vivo but that it is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags.

Aminopeptidase Puromycin Sensitive (NPEPPS) Antigen Profile

Protein Summary

This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.

Gene names and symbols associated with NPEPPS

  • Puromycin sensitive aminopeptidase (Psa) antibody
  • puromycin-sensitive aminopeptidase (LOC410769) antibody
  • aminopeptidase puromycin sensitive (npepps) antibody
  • aminopeptidase puromycin sensitive (NPEPPS) antibody
  • aminopeptidase puromycin sensitive L homeolog (npepps.L) antibody
  • puromycin-sensitive aminopeptidase (npepps) antibody
  • puromycin-sensitive aminopeptidase (Npepps) antibody
  • aminopeptidase puromycin sensitive (Npepps) antibody
  • AAP-S antibody
  • CG1009 antibody
  • Dmel\\CG1009 antibody
  • dPsa antibody
  • fb68d07 antibody
  • GB13772 antibody
  • goku antibody
  • l(3)06226 antibody
  • MGC147526 antibody
  • MP100 antibody
  • npepps antibody
  • psa antibody
  • R74825 antibody
  • sb:cb848 antibody
  • wu:fb68d07 antibody

Protein level used designations for NPEPPS

CG1009-PA , CG1009-PB , CG1009-PC , CG1009-PD , CG1009-PE , CG1009-PF , CG1009-PH , CG1009-PI , Psa-PA , Psa-PB , Psa-PC , Psa-PD , Psa-PE , Psa-PF , Psa-PH , Psa-PI , lethal (3) 06226 , puromycin sensitive aminopeptidase , puromycin-sensitive-aminopeptidase , puromycin-sensitive aminopeptidase , aminopeptidase puromycin sensitive , puromycin-sensitive aminopeptidase-like , cytosol alanyl aminopeptidase , metalloproteinase MP100

GENE ID SPECIES
38175 Drosophila melanogaster
410769 Apis mellifera
407726 Danio rerio
426231 Gallus gallus
480538 Canis lupus familiaris
534122 Bos taurus
693995 Macaca mulatta
733291 Xenopus laevis
749281 Pan troglodytes
780147 Xenopus (Silurana) tropicalis
8956886 Sphingobium japonicum UT26S
100019211 Monodelphis domestica
100069104 Equus caballus
100350778 Oryctolagus cuniculus
100373801 Saccoglossus kowalevskii
100409612 Callithrix jacchus
100439609 Pongo abelii
100479817 Ailuropoda melanoleuca
9520 Homo sapiens
19155 Mus musculus
50558 Rattus norvegicus
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