Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Proteins (APBA3)

The protein encoded by APBA3 is a member of the X11 protein family. Additionally we are shipping Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Antibodies (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APBA3 57267 O88888
APBA3 9546 O96018
APBA3 83611 O70248
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Top Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,371.15
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,371.15
Details
Escherichia coli (E. coli) Human His tag   50 μg 4 Days
$522.50
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg 4 to 8 Days
$396.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
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Yeast Rat His tag   1 mg 60 to 71 Days
$3,631.83
Details
Escherichia coli (E. coli) Human His tag   10 μg 15 to 16 Days
$300.00
Details

APBA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) Interaction Partners

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) interaction partners

  1. APBA3-deficient mice show reduced metastasis, with no apparent effect on primary tumor growth. APBA3 deficiency in inflammatory monocytes hampers glycolysis-dependent chemotaxis of cells toward metastatic sites.

  2. we have identified Mint3 as a physiological positive regulator of TLR3/4 and RIG-I-induced IFN-beta production and have outlined a feedback mechanism for the control of antiviral immune responses.

  3. Mint3 depletion attenuated metastasis to the lungs in breast cancer model mice.

  4. Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock.

  5. Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV

  6. Mints are important regulators of presynaptic neurotransmitter release that are essential for mouse survival.

  7. Binding of Munc18-1 to closed, target-SNARE syntaxin 1 stimulates vesicle docking and regulates the consecutive priming step during exocytosis of secretory or synaptic vesicles.

  8. X11L2 functions in the nucleus by a mechanism distinct from conventional transactivators

Human Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) interaction partners

  1. Results suggest that NECAB3, a novel Mint3-binding protein, activates HIF-1 to promote normoxic glycolysis and tumorigenicity by forming a ternary complex with Mint3 and FIH-1.

  2. FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.

  3. Mints are necessary for activity-induced APP and PS1 trafficking and provide insight into the cellular fate of APP in endocytic pathways essential for Abeta production.

  4. Strict specificity for recruitment of the Mint3 adaptor by APP at the Golgi, a critical role for Tyr-682 (within the YENPTY motif) in Mint3 recruitment and export of APP from the Golgi, are demonstrated.

  5. These results indicate that all three amyloid beta protein precursor family members are capable of activating gene transcription via Mint3-Taz and Mint3-Yap.

  6. Two transcriptional coactivators, TAZ and YAP, functionally associate with amyloid precursor protein through Mint3 and form transcriptionally active triple protein complexes.

  7. Associated with etilogical mechanism of Alzheimer's disease.

  8. Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV

  9. We have examined the ability of Bcr to interact with other epithelial PDZ proteins and found specific binding to both the apical PDZK1 protein and the Golgi-localized Mint3

  10. These data implicate Mint3 activity as a critical determinant of post-Golgi APP traffic.

  11. the interaction between the PTB domain of Mint3 and the acidic peptide signal of Furin regulates the specific localization of Furin in the trans-Golgi network

  12. Mint3 regulates the FIH-1-HIF-1 pathway, which controls ATP production in macrophages

Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.

Gene names and symbols associated with APBA3

  • amyloid beta precursor protein binding family A member 3 (APBA3)
  • amyloid beta (A4) precursor protein-binding, family A, member 3 (Apba3)
  • amyloid beta precursor protein binding family A member 3 (Apba3)
  • AW208791 protein
  • lin-10 protein
  • MGC:15815 protein
  • Mint-3 protein
  • Mint3 protein
  • X11gamma protein
  • X11L2 protein

Protein level used designations for APBA3

amyloid beta (A4) precursor protein-binding, family A, member 3 , Mint 3 , adapter protein X11gamma , amyloid beta A4 precursor protein-binding family A member 3 , neuron-specific X11L2 protein , neuronal munc18-1-interacting protein 3 , X11-like 2 protein , amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) , mint-3 , phosphotyrosine-binding/-interacting domain (PTB)-bearing protein , amyloid beta (A4) precursor protein-binding family A member 3 (X11-like 2) , amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) , neuronal Munc18-1-interacting protein 3

GENE ID SPECIES
100021747 Monodelphis domestica
57267 Mus musculus
9546 Homo sapiens
485053 Canis lupus familiaris
83611 Rattus norvegicus
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