Human APOB ELISA Kit for Sandwich ELISA - ABIN2683473
:
Adiloglu, Can, Kinay, Aridogan: Infection with Chlamydia pneumoniae but not Helicobacter pylori is related to elevated apolipoprotein B levels. in Acta cardiologica 2006
(PubMed)
Show all 5 Pubmed References
Mouse (Murine) APOB ELISA Kit for Sandwich ELISA - ABIN1874344
:
Hollie, Hui: Group 1B phospholipase A? deficiency protects against diet-induced hyperlipidemia in mice. in Journal of lipid research 2011
(PubMed)
Show all 5 Pubmed References
Mouse (Murine) APOB ELISA Kit for Competition ELISA - ABIN832336
:
Hu, Yang, Ma, Chen, Hu, Zhao, Li, Qiu, Lu, Wang, Gao, Sha, Zheng, Wang: A lincRNA-DYNLRB2-2/GPR119/GLP-1R/ABCA1-dependent Signal Transduction Pathway Is Essential for the Regulation of Cholesterol Homeostasis and Inflammatory Reactions. in Journal of lipid research 2014
(PubMed)
Show all 2 Pubmed References
Human APOB ELISA Kit for Sandwich ELISA - ABIN417290
:
Morikawa, Maranhão, Alves, Negrão, da Silva, Vinagre: Effects of anabolic androgenic steroids on chylomicron metabolism. in Steroids 2012
(PubMed)
Show all 2 Pubmed References
Human APOB ELISA Kit for Sandwich ELISA - ABIN612664
:
Butt, Bernhardt, Smolenski, Kotsonis, Fröhlich, Sickmann, Meyer, Lohmann, Schmidt: Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases. in The Journal of biological chemistry 2000
(PubMed)
Show all 11 Pubmed References
Mouse (Murine) APOB ELISA Kit for Sandwich ELISA - ABIN832333 : Hu, Hu, Zhao, Li, Ma, Wu, Lu, Qiu, Sha, Wang, Gao, Zheng, Wang: An agomir of miR-144-3p accelerates plaque formation through impairing reverse cholesterol transport and promoting pro-inflammatory cytokine production. in PLoS ONE 2014 (PubMed)
Mouse (Murine) APOB ELISA Kit for Sandwich ELISA - ABIN1113522 : Smallwood, Gatti, Quizon, Weinstock, Jung, Zhao, Hua, Pomp, Bennett: High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis. in G3 (Bethesda, Md.) 2014 (PubMed)
Human APOB ELISA Kit for Sandwich ELISA - ABIN415222 : Pramfalk, Larsson, Härdfeldt, Eriksson, Parini: Culturing of HepG2 cells with human serum improve their functionality and suitability in studies of lipid metabolism. in Biochimica et biophysica acta 2015 (PubMed)
Rat (Rattus) APOB ELISA Kit for Sandwich ELISA - ABIN416208 : Zhang, Kallenberg, Hyatt, Kavazis, Hood: Change in the Lipid Transport Capacity of the Liver and Blood during Reproduction in Rats. in Frontiers in physiology 2017 (PubMed)
This study shows that the ApoB-516C/T promoter gene polymorphism has no impact on the risk of hepatitis C virus infection. However, the C/T genotype may be a protective factor for females.
association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns
that apos involved in TG metabolism such as apoC2 (show APOC2 ELISA Kits), C3, E, and A4 (micromolar concentration), and apoB48 and apoA5 (show APOA5 ELISA Kits) (single-digit nanomolar concentration) can be quantified from a single digestion mixture.
These findings indicate that maternal apo (show C9orf3 ELISA Kits) B levels are significantly associated with apo (show C9orf3 ELISA Kits) B levels in their pre-school age children, adjusted for confounding variables. Furthermore, the mother-child correlations in apo (show C9orf3 ELISA Kits) B levels were independent of mother-child adiposity. Measurement of apo (show C9orf3 ELISA Kits) B levels in mothers may identify both high-risk children and mothers who may benefit from intervention.
Individuals with apoB higher than predicted by non-HDL (show HSD11B1 ELISA Kits)-C had significantly higher levels of PAI-1 (show SERPINE1 ELISA Kits), which may contribute to the increased risk of future atherothrombotic events
analysis of five likely pathogenic heterozygous rare variants that include four novel nonsense mutations in APOB (p.Gln845*, p.Gln2571*, p.Cys2933* and p.Ser3718*) and a rare variant in PCSK9 (show PCSK9 ELISA Kits) (Minor Allele Frequency <0.1%).
The impact of smoking on the levels of apolipoprotein B (APOB) was evaluated by analyzing data from NHANES for the years 2007-2012 for US adolescents aged 12-19 years and adults aged greater than or eqult to 20 years. The study found that smoking did not influence the observed levels of APOB for either adolescents or adults.
Identify LDLR (show LDLR ELISA Kits), APOB and PCSK9 (show PCSK9 ELISA Kits) novel mutations causing familial hypercholesterolemia in the central south region of China.
Rare variants of APOB or PCSK9 (show PCSK9 ELISA Kits) were identified in nine of the 22 study patients with extremely low LDL-C levels
Eicosapentaenoic acid has direct antioxidant benefits in various apoB-containing subfractions.
enhanced VLDL TG secretion in the absence of hepatocyte ABCA1 (show ABCA1 ELISA Kits) is due to altered intracellular trafficking of apolipoprotein B (apoB), resulting in augmented TG addition to nascent VLDL.
We carried out our experiment in mice deficient in the low density lipoprotein (LDL) receptor (show LDLR ELISA Kits) and expressing only ApoB100 molecule (ApoB - LDLr (show LDLR ELISA Kits)) where the development of atherosclerosis is known to closely mimic human atherosclerosis
The effect of hypercholesterolemia induced immune response and inflammation on progression of atherosclerosis in ApoB(tm25gy) LDLr (show LDLR ELISA Kits)(tm1Her) mice, expressing only ApoB100 and deficient in the low density lipoprotein receptor (show LDLR ELISA Kits).
ApoB-containing lipoproteins contribute to augmentation of AngII-induced abdominal aortic aneurysms in male mice.
Immunization with human apolipoprotein B100 (ApoB) resulted in four-fold increased accumulation of effector T cells in ApoB-containing matrigel
PCSK9 (show PCSK9 ELISA Kits) markedly increases intestinal triglyceride-rich apoB production through mechanisms mediated in part by transcriptional effects on apoB.
Mice that produce apoB100 in the RPE and liver secrete lipoproteins into Bruch's membrane, but not to the extent that distinct features of AMD (show AMD1 ELISA Kits) develop
The aim of this study was to characterize the ocular morphology of low-density lipoprotein receptor-deficient apolipoprotein B-100-only mice, with IGF-II overexpression.
Our data establish the role of APOB gene in severe gut (show GUSB ELISA Kits) dysmotility.
Cardiac lipotoxicity may originate from direct inhibition of myocardial ApoB lipoprotein and subsequent decreased lipid export, caused by supraphysiological levels of catecholamines.
The clinicopathological phenotype of affected Holstein cattle homozygous for the causative apolipoprotein B gene (APOB) mutation associated with cholesterol deficiency is described.
Beyond malabsorption of dietary lipids, deleterious effects of apolipoprotein B deficiency on hepatic lipid metabolism, steroid biosynthesis, and cell membrane function can be expected, which may result in unspecific symptoms of reduced fertility, growth, and health.
Cholesterol deficiency results from a 1.3kbp insertion of an endogenous retrovirus (ERV2-1-LTR_BT) into exon 5 of the APOB gene at BTA11:77,959kb. The insertion is flanked by 6bp target site duplications as described for insertions mediated by retroviral integrases.
A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle
Nonesterified fatty acids significantly inhibit the expression of ApoB100, ApoE (show APOE ELISA Kits), MTP (show MTTP ELISA Kits), and LDLR (show LDLR ELISA Kits), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.
after calving the apolipoprotein B(100) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (show MTTP ELISA Kits)) and apolipoprotein E (show APOE ELISA Kits) messenger RNA abundance were higher in the liver.
found association between genotypes for LDLR (show LDLR ELISA Kits) and APOB polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
apo B-100 , apoB-100 , apoB-48 , apolipoprotein B (including Ag(x) antigen) , apolipoprotein B-100 , apolipoprotein B48 , mutant Apo B 100 , apolipoprotein B PI , apolipoprotein B-48 , apolipoprotein B
GENE ID | SPECIES |
---|---|
338 | Homo sapiens |
54225 | Rattus norvegicus |
238055 | Mus musculus |
494004 | Bos taurus |
702937 | Macaca mulatta |
100009101 | Oryctolagus cuniculus |
100523371 | Sus scrofa |
396535 | Gallus gallus |
100725937 | Cavia porcellus |
475680 | Canis lupus familiaris |
101107590 | Ovis aries |