anti-Apolipoprotein L, 1 (APOL1) Antibodies

APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Additionally we are shipping APOL1 Kits (23) and APOL1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APOL1 8542 O14791
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Top anti-APOL1 Antibodies at

Showing 10 out of 136 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN308434 (1µg/ml) staining of Human Frontal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
Human Rabbit Un-conjugated WB Host: Rabbit Target Name: APOL1 Sample Type: Human OVCAR-3  Lane A: Primary Antibody  Lane B: Primary Antibody + Blocking Peptide  Primary Antibody Concentration: 1.0 ug/ml Peptide Concentration: 2.0 ug/ml Lysate Quantity: 25 ug/lane WB Suggested Anti-APOL1 Antibody Titration: 1.0 ug/ml Positive Control: OVCAR-3 Whole Cell APOL1 is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL 2 to 3 Days
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
Human Rabbit Un-conjugated WB Western blot analysis of Apolipoprotein L1 expression in MCF7 (A), HeLa (B), NS-1 (C), PC12 (D) whole cell lysates. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549 cells, using APOL1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Human Rabbit Un-conjugated EIA, WB   0.4 mL 4 to 8 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg 2 to 3 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Human MCF7 Cells. Figure. Western Blot; Sample: Recombinant APOL1, Human. 100 μg 13 to 16 Days
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Available
Human Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days

Top referenced anti-APOL1 Antibodies

  1. Human Polyclonal APOL1 Primary Antibody for IHC, IHC (p) - ABIN4281231 : Madhavan, OToole, Konieczkowski, Ganesan, Bruggeman, Sedor: APOL1 localization in normal kidney and nondiabetic kidney disease. in Journal of the American Society of Nephrology : JASN 2011 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal APOL1 Primary Antibody for ELISA, WB - ABIN968963 : Vanhollebeke, Nielsen, Watanabe, Truc, Vanhamme, Nakajima, Moestrup, Pays: Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal APOL1 Primary Antibody for ELISA, WB - ABIN449525 : Pérez-Morga, Vanhollebeke, Paturiaux-Hanocq, Nolan, Lins, Homblé, Vanhamme, Tebabi, Pays, Poelvoorde, Jacquet, Brasseur, Pays: Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against APOL1 Interaction Partners

Human Apolipoprotein L, 1 (APOL1) interaction partners

  1. data showing no cytotoxicity of overexpressed APOL1 isoform lacking exon 4, we propose that morpholino-induced APOL1 isoform switch may provide a new tool to identify in vivo molecular mechanism(s) by which risk alleles promote or mediate the kidney disease phenotype.

  2. Our results indicate that APOL1-mediated pore formation is critical for the trypanolytic activity of APOL1 and drives APOL1-mediated cytotoxicity in overexpression systems.

  3. There are striking differences in chronic kidney disease between Caucasians and African descendants. It was widely accepted that this occurred due to socioeconomic factors, but recent studies show that apolipoprotein L-1 (APOL1) gene variants are strongly associated with focal segmental glomerulosclerosis, HIV-associated nephropathy, hypertensive nephrosclerosis, and lupus nephritis in the African American population

  4. Modulation of the APOL1-miR193a axis carries a potential to preserve podocyte molecular phenotype in high glucose milieu.

  5. APOL1 renal-risk variant protein has a role in the development of nephropathy; this is true in both native kidney disease and after renal transplantation [review]

  6. APOL1 high-risk status is associated with CVD events in community-dwelling Black adults without diabetes mellitus.

  7. ApoL1 variants regulate monocyte differentiation into macrophages and eicosanoid metabolism via enhanced COX-2 expression.

  8. Among blacks without baseline CVD, the APOL1 high-risk variants may be associated with increased risk for incident heart failure but not subclinical CVD or incident clinical atherosclerotic CVD.

  9. Donor APOL1 high-risk genotypes are associated with inferior graft survival and de novo collapsing focal segmental glomerulosclerosis with high proteinuria after kidney transplantation.

  10. Individual genome-wide association studies and meta-analysis results of 2650 end-stage renal disease (ESRD) cases and 1656 controls African American patients did not detect significant genome-wide associations with ESRD beyond APOL1. Similarly, no single nucleotide polymorphism showed significant genome-wide evidence of an interaction with APOL1 risk variants. [meta-analysis]

  11. Fetal APOL1 high-risk genotype increases the risk for preeclampsia, likely by adversely affecting placental function.

  12. These studies establish APOL1 as a bona fide LD-associated protein, and reveal that recruitment of risk variant APOL1 to LDs reduces cell toxicity, autophagic flux, and cell death.

  13. APOL1 genotype may not be sufficient to explain discrepancies in postdonation kidney function between caucasian donors and low-risk APOL1 genotype living kidney donors of African ancestry.

  14. APOL1 risk variants contribute to podocyte injury through enhanced endoplasmic reticulum stress. The study provides insight into new mechanisms involved in APOL1 risk variants-induced podocyte damage, and highlights some new therapeutic targets for APOL1-associated nephropathy.

  15. Apolipoprotein L1 risk variants are present in black South Africans with similar frequencies between chronic kidney disease patients, first-degree relatives, and healthy controls.

  16. Plasma concentrations of TNFR1, TNFR2, and KIM1 are independently associated with renal outcome and improve discrimination or reclassification of African ancestry individuals with a high-risk APOL1 genotype and preserve renal function.

  17. APOL1 risk variants did not associate with subclinical markers of atherosclerosis or left ventricular hypertrophy in middle-aged black adults with preserved kidney function.

  18. Review of the role of APOL1 in kidney disease in children and young adults of African ancestry. APOL1 explains almost 70% of the excess risk of kidney disease in those of African descent, and is common in children with glomerular disease.

  19. Association of chronic kidney disease with APOL1 risk alleles was not identified in Aboriginal people in remote areas of Australia.

  20. APOL1 Risk Variant is associated with focal segmental glomerulosclerosis.

Zebrafish Apolipoprotein L, 1 (APOL1) interaction partners

  1. zApoL1 is essential for proper blood filtration in the zebrafish glomerulus and that zApoL1 affects the expression of nephrin

APOL1 Antigen Profile

Protein Summary

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with APOL1

  • apolipoprotein L1 (APOL1) antibody
  • apolipoprotein L, 1 (apol1) antibody
  • APO-L antibody
  • APOL antibody
  • APOL-I antibody
  • FSGS4 antibody
  • si:rp71-1g18.12 antibody
  • wu:fa95b12 antibody
  • wu:fc30h04 antibody

Protein level used designations for APOL1

apolipoprotein L1

8542 Homo sapiens
560340 Danio rerio
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