Apolipoprotein L, 1 Proteins (APOL1)

APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Additionally we are shipping APOL1 Antibodies (122) and APOL1 Kits (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOL1 8542 O14791
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top APOL1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 20 to 21 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human GST tag,S tag,His tag 100 μg Log in to see 15 to 18 Days

APOL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,

More Proteins for Apolipoprotein L, 1 (APOL1) Interaction Partners

Zebrafish Apolipoprotein L, 1 (APOL1) interaction partners

  1. zApoL1 is essential for proper blood filtration in the zebrafish glomerulus and that zApoL1 affects the expression of nephrin (show NPHS1 Proteins)

Human Apolipoprotein L, 1 (APOL1) interaction partners

  1. APOL1 variant is associated with End-Stage Renal Disease.

  2. The enhanced expression of GRP78 (show HSPA5 Proteins) by podocytes expressing APOL1 variants would indicate endoplasmic reticulum (ER) stress.

  3. Among patients with CKD attributed to hypertension, those with the APOL1 high-risk genotype were more likely to experience a steady decline trajectory in eGFR (show EGFR Proteins) than those without the APOL1 high-risk genotype. These findings suggest a persistent underlying pathophysiologic process in those patients with the APOL1 high-risk genotype.

  4. APOL1 Gene variation is associated with end-stage renal disease.

  5. Apolipoprotein L1 and apolipoprotein A-IV (show APOA4 Proteins) and their association with kidney function

  6. Data suggest that APOL1 confers chloride-selective permeability to preformed phospholipid vesicles; this selectivity is strongly pH-sensitive, with maximal activity at pH 5 and little activity above pH 7; APOL1 permease activity requires calcium ions; APOL1 stably associates with phospholipid vesicles, requiring low pH and presence of negatively charged phospholipids for maximal binding.

  7. Strict blood pressure control during chronic kidney disease associates with a lower risk of death in blacks with the high-risk CKD APOL1 genotype.

  8. Divergent intracellular biological pathways of ancestral and variant APOL1 may explain a worsened prognosis as demonstrated in Systemic Lupus Erythematosus.

  9. Roles of APOL1 G1 and G2 variants in sickle cell disease patients: kidney is the main target.

  10. Two APOL1 renal-risk variants are associated with longer dialysis survival in African Americans with non-diabetic end-stage renal disease.

APOL1 Protein Profile

Protein Summary

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Apolipoprotein L, 1 Proteins (APOL1)

  • apolipoprotein L, 1 (apol1)
  • apolipoprotein L1 (APOL1)
  • APO-L protein
  • APOL protein
  • APOL-I protein
  • FSGS4 protein
  • si:rp71-1g18.12 protein
  • wu:fa95b12 protein
  • wu:fc30h04 protein

Protein level used designations for Apolipoprotein L, 1 Proteins (APOL1)

apolipoprotein L1

560340 Danio rerio
8542 Homo sapiens
Selected quality suppliers for APOL1 Proteins (APOL1)
Did you look for something else?