Apolipoprotein L, 1 Proteins (APOL1)

APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Additionally we are shipping APOL1 Antibodies (137) and APOL1 Kits (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APOL1 8542 O14791
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Top APOL1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 20 to 21 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human GST tag,S tag,His tag 100 μg Log in to see 15 to 18 Days

APOL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,

More Proteins for Apolipoprotein L, 1 (APOL1) Interaction Partners

Zebrafish Apolipoprotein L, 1 (APOL1) interaction partners

  1. zApoL1 is essential for proper blood filtration in the zebrafish glomerulus and that zApoL1 affects the expression of nephrin (show NPHS1 Proteins)

Human Apolipoprotein L, 1 (APOL1) interaction partners

  1. APOL1, alpha-thalassemia, and BCL11A (show BCL11A Proteins) variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia.

  2. Among blacks with established moderate CKD, the APOL1 high-risk variants are associated with greater risk of incident proteinuria. After proteinuria onset, kidney function declines more rapidly but does not differ by APOL1 risk status.

  3. In individuals at risk for nondiabetic kidney disease based on African ancestry, the majority of that risk can be explained by two variants in the APOL1 gene.

  4. Considering APOL1 evolution also may help us understand how APOL1 risk variants cause kidney disease in modern humans.

  5. APOL1 variants are associated with HIV-associated nephropathy(HIVAN), a podocyte disease,but not with HIV-immune complex disease, primarily a disease of the mesangium.

  6. the associations of the APOL1 risk variants with microalbuminuria, incident CKD, and subsequent kidney function decline implicate a potential role in both the development and progression of CKD. Unlike the consistent association with CKD, the association of the APOL1 risk variants with cardiovascular disease is less clear.

  7. The presence of two APOL1 renal risk variants in deceased donors shortens survival of their renal allografts. No study has examined the potential interaction of APOL1 genotype of the donors, deceased or living, and recipients.

  8. expression of G1 or G2 APOL1 results in significantly more cell death compared with wild-type APOL1 (G0) in various human cells in culture

  9. Genetic variant in apolipoprotein L1 is not associated with preterm birth in African American population.

  10. This is the first report of a specific association of APOL1 with small vessel disease (SVD (show KCNJ13 Proteins)) ischemic stroke.

APOL1 Protein Profile

Protein Summary

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Apolipoprotein L, 1 Proteins (APOL1)

  • apolipoprotein L, 1 (apol1)
  • apolipoprotein L1 (APOL1)
  • APO-L protein
  • APOL protein
  • APOL-I protein
  • FSGS4 protein
  • si:rp71-1g18.12 protein
  • wu:fa95b12 protein
  • wu:fc30h04 protein

Protein level used designations for Apolipoprotein L, 1 Proteins (APOL1)

apolipoprotein L1

560340 Danio rerio
8542 Homo sapiens
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