anti-Aquaporin 5 (AQP5) Antibodies

Aquaporin 5 (AQP5) is a water channel protein. Additionally we are shipping Aquaporin 5 Kits (48) and Aquaporin 5 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AQP5 362 P55064
AQP5 11830 Q9WTY4
AQP5 25241 P47864
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Top anti-Aquaporin 5 Antibodies at antibodies-online.com

Showing 10 out of 114 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Anti-Aquaporin 5 antibody, Western blotting Lane 1: MM453 Cell Lysate Lane 2: MM231 Cell Lysate Lane 3: SMMC Cell Lysate Lane 4: SW620 Cell Lysate 100 μg Log in to see 4 to 6 Days
$240.00
Details
Rat Rabbit Un-conjugated IHC (p), WB Anti-Aquaporin 5 antibody, Western blotting Lane 1: Rat Lung Tissue Lysate Lane 2: Rat Testis Tissue Lysate Anti-Aquaporin 5 antibody, IHC(P) IHC(P): Rat Lung Tissue Lysate 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: AQP5 Sample Type: COLO205 Whole cell lysates Antibody Dilution: 1.0ug/ml  AQP5 is supported by BioGPS gene expression data to be expressed in COLO205 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney labeled with Anti-AQP5 Polyclonal Antibody, Unconjugated (ABIN731258) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-AQP5 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Aquaporin 5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Aquaporin 5 expression in MCF7 (A), Jurkat (B), SP2/0 (C), PC12 (D), KNRK (E) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, WB AQP5 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35µg/lane).This demonstrates the AQP5 antibody detected the AQP5 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB AQP5 Antibody (C-term) (ABIN656235) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the AQP5 antibody detected the AQP5 protein (arrow). Overlay histogram showing U-2 OS cells stained with ABIN2845551 (green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (ABIN2845551, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(1583138) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG1 (1μg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. Dilution: 1:25 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see Available
$181.73
Details
Mouse Rabbit Un-conjugated IHC, WB IHC on paraffin sections of mouse cerebellum tissue using Rabbit antibody to AQP5 (215-265): .HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module.Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm.Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions.Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer).Sections were counterstained with Harris Hematoxylin. IHC on paraffin sections of mouse cerebellum tissue using Rabbit antibody to AQP5 (215-265): .HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module.Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm.Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions.Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer).Sections were counterstained with Harris Hematoxylin. 100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$280.00
Details

Top referenced anti-Aquaporin 5 Antibodies

  1. Human Polyclonal Aquaporin 5 Primary Antibody for IF (p), IHC (p) - ABIN731258 : Wang, Li, Yang, Bai, Li, Li, Sun: Expression of AQP5 and AQP8 in human colorectal carcinoma and their clinical significance. in World journal of surgical oncology 2012 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal Aquaporin 5 Primary Antibody for WB - ABIN3042674 : Chen, Zhou, Yan, Ma, Zheng: Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression. in Experimental and therapeutic medicine 2015 (PubMed)
    Show all 2 Pubmed References

  3. Rat (Rattus) Polyclonal Aquaporin 5 Primary Antibody for IHC (p), WB - ABIN3043712 : Guo, Kazadaeva, Ortega, Manjunath, Desai: Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. in Developmental biology 2017 (PubMed)
    Show all 2 Pubmed References

  4. Polyclonal Aquaporin 5 Primary Antibody for WB - ABIN540601 : Ma, Yang, Umenishi, Verkman: Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13. in Genomics 1997 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Aquaporin 5 Interaction Partners

Human Aquaporin 5 (AQP5) interaction partners

  1. results suggest regulation of AQP1 and AQP5 at the post-translational level and support previous observations on the implication of AQP1 and 5 in maintenance of lens transparency

  2. Results show that the exposure to a hyperosmotic challenge induces AQP5 upregulation along with increases in expression levels of proinflammatory cytokines and cell death through increases in the JNK1/2 MAPK signaling pathway in human corneal epithelial cells.

  3. the present data suggest that expression of AQP3 and 5 may be a marker for distinguishing between patients with dry mouth and those with Sjogren's syndrome

  4. Results indicate that autophagy plays a crucial role in aquaporin 5 (AQP5) degradation in diabetic submandibular gland (SMG).

  5. these results suggest that AQP5 silencing enhances the sensitivity of colorectal cancer (CRC) cells to 5-FU, and the underlying mechanism is related to inhibition of the Wnt-beta-catenin pathway. AQP5 could be a useful therapeutic target for CRC treatment.

  6. Down-regulation of Apaf-1 protein and the overexpression of Cyclin D1 and AQP-5 proteins possibly contribute to an aggressive serous ovarian carcinoma with a high risk of recurrence and poor response to the first-line chemotherapy.

  7. Structural basis for mutations in human AQP5 associated with keratoderma has been described.

  8. The urea transporter subtypes, UT-A1 and UT-B1, were expressed in the skin basal cell layer and exocrine sweat glands. The abundance of UT-A1 and UT-B1 in uremic sweat glands was significantly increased in UP, while the expression of AQP5 was decreased.

  9. AQP1, 3 and 5 expression through the stages of human salivary gland morphogenesis, was examined.

  10. we demonstrated that AQP5 gene silencing could inhibit the proliferation, reduce the migration and promote the apoptosis of human glioma cells by suppressing EGFR/ERK/p38 MAPK signaling pathway

  11. Data suggest that urine AQP5/creatinine ratio is significantly higher in patients with diabetic nephropathy than in control subjects, subjects diabetes, or subjects with nephropathy of unknown etiology; urine AQP5/creatinine ratio increases with stage of diabetic nephropathy; this biomarker may improve clinical models in distinguishing diabetic nephropathy from normal controls and subjects with type 2 diabetic alone.

  12. We present the first Danish family diagnosed with autosomal dominant palmplantar ketratoderma of Bothnian type resulting from c.562C>T, p.Arg188Cys in the AQP5 gene.

  13. Findings show that overexpression of aquaporin 5 (AQP5) activated epithelial-mesenchymal transition (EMT) in colorectal cancer (CRC) cells.

  14. Osmotic water permeabilities of aquaporins AQP4, AQP5, and GlpF from near-equilibrium simulations have been presented.

  15. RAQP5 protein expression in breast cancer.Rac1 is a potential downstream signaling partner of AQP5 in breast cancer.

  16. The AQP5 genotype may influence survival following lipopolysaccharides by altering neutrophil cell migration.

  17. Mucins and AQP5 gene expression were significantly higher in patients with OME relative to controls. A 2-fold increase in AQP5 correlated with increased effusion viscosity (1.94 mL/mg; 95% CI, 0.08-3.80 mL/mg).

  18. The severity of preterm infants with acute respiratory distress syndrome was associated with the plasma level of AQP5; the more severe of the disease, the higher levels of plasma AQP5.

  19. AQP5 is up-regulated in hepatocellular carcinoma (HCC) cell line. AQP5 promotes hepatocellular carcinoma metastasis via NF-kappa B-regulated epithelial-mesenchymal transition.

  20. Double IF showed the co-localization of AQP5 and LC3B on BafA1-treated heated cells. In conclusion, we demonstrated that heat shock decreased AQP5 on cellular membranes and in the cytoplasm by activating autophagic degradation, and heat shock and AQP5 knockdown exerted similar anticancer effects, suggesting that heat shock exerts anticancer effects via the autophagic degradation of AQP5.

Mouse (Murine) Aquaporin 5 (AQP5) interaction partners

  1. AQP5 forms functional water channels in the rodent lens, and suggest that dynamic membrane insertion of AQP5 may regulate water fluxes in the lens by modulating water permeability in the outer cortex.

  2. Cooperative interactions among transcription factors and histone modifications regulate Aqp5 expression during alveolar epithelial cell transdifferentiation, suggesting that HDAC inhibitors may enhance repair by promoting acquisition of AT1 cell phenotype.

  3. Results indicate that autophagy plays a crucial role in aquaporin 5 (AQP5) degradation in diabetic submandibular gland (SMG).

  4. A daily rhythm was detected in the expression profiles of Aqp5 in submandibular glands in vivo.

  5. AQP5 immunoreactivity was found in the isthmic muscle and lamina propria beneath the epithelia. In cycling females, oviduct aqp5 mRNA levels were the highest at oestrus and the lowest at dioestrus. AQP5 immunoreactivity in non-ciliated cells was notable in the infundibulum, where AQP5 was relatively high at oestrus but low at dioestrus & pro-oestrus, indicating synchrony between aqp5 gene activation and the ovarian cycle.

  6. RUNX1 is essential for the development of the granular convoluted tubules in the submandibular glands; RUNX1 could also be involved in the membrane trafficking of the AQP5 protein of the acinar cells in the SMG in order to allow for the proper secretion of saliva

  7. The AQP5 genotype may influence survival following lipopolysaccharides by altering neutrophil cell migration.

  8. Adjusting AQP5 protein levels could be considered a therapeutic strategy for the treatment of acute pulmonary edema induced by H2S and other hazardous gases

  9. GTP-dependent AQP5 expression could act as osmosensor

  10. AQP5 promoter methylation is not a universal mechanism for AQP5 regulation.

  11. The activation of P2X7 receptor was connected with an increase of aquaporin-5, whereas the inhibition of the receptor with oxidized ATP resulted in down regulation of aquaporin-5.

  12. Lung AQP1 and AQP5 expression were significantly decreased in mice with acute lung injury together with increased inflammatory reaction and apoptosis of alveolar epithelial and vascular endothelial cells

  13. The co-regulation of pendrin and AQP5 membrane expression under chronic K(+)-deficiency indicates that these two molecules could cooperate as an osmosensor to rapidly detect and respond to alterations in luminal fluid osmolality.

  14. propose a new function of AQP5 as an inflammatory signal potentiator, which may be mediated by increased activation of ERK and NF-kappaB

  15. AQP5 plays an important role in high altitude pulmonary edema formation induced by high altitude simulation.

  16. Administration of cevimeline maintains the proper localization of AQP-5 in the acinar cells of the salivary glands of mice with Sjogren's syndrome.

  17. this is the first report providing evidence that AQP5 facilitates maintenance of lens transparency and homeostasis by regulating osmotic swelling caused by glucose transporters and cotransporters under hyperglycemic stressful conditions.

  18. The regulated AQP5 translocation may contribute to sweat secretion by increasing the water permeability of apical plasma membranes of sweat glands.

  19. Hypoxia decreases aquaporin 5 (AQP5) expression through both hypoxia inducible factor-1alpha and proteasome-mediated pathways.

  20. upregulated Aqp5 may contribute to polyuria, possibly by impairing Aqp2 membrane localization, in Dot1l(AC) mice and in patients with diabetic nephropathy.

Cow (Bovine) Aquaporin 5 (AQP5) interaction partners

  1. AQP5 is a significant component of lens fiber cell membranes, representing the second most abundant water channel in these cells.

Pig (Porcine) Aquaporin 5 (AQP5) interaction partners

  1. Quantitative real-time PCR analysis showed markedly decreased mRNA levels of AQP1 and AQP5 and Na,K-ATPase in the Porcine reproductive and respiratory syndrome virus (PRRSV) -infected pig lungs compared to those of uninfected pig lungs.

  2. These results suggest a participation of steroid hormones (P4 and E2), AA derivatives and cAMP in controlling the expression of AQP1 and AQP5 as well as the distribution of AQP5 in the uterine tissue of pregnant gilts during placentation (Days 30 - 32 of gestation).

  3. up-regulated by progesterone, estradiol, arachidonic acid, forskolin, and cyclic AMP in the uterus during the embryo implantation period

  4. aquaporin 5 appears to be a potential regulator of follicular fluid accumulation, under androgen control, and may be a key factor in antral follicle growth

  5. AQP1 and 5 seem to be crucial for follicular development in pigs

  6. A functional and distinctive collaboration exists among diverse AQPs in water handling during the different uterine phases in the estrous cycle and early pregnancy.

  7. Several subtypes of the AQPs (AQP1, 5, and 9) are involved in regulation of water homeostasis in the reproductive system of gilts.

Aquaporin 5 (AQP5) Antigen Profile

Protein Summary

Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.

Gene names and symbols associated with anti-Aquaporin 5 (AQP5) Antibodies

  • aquaporin 5 (AQP5) antibody
  • aquaporin 5 (Aqp5) antibody
  • aquaporin-5 (LOC711804) antibody
  • aquaporin-5 (LOC100231329) antibody
  • AQP-5 antibody
  • AQP5 antibody
  • LOC100231329 antibody

Protein level used designations for anti-Aquaporin 5 (AQP5) Antibodies

aquaporin-5 , AQP-5 , water channel , aquaporin 5

GENE ID SPECIES
362 Homo sapiens
11830 Mus musculus
25241 Rattus norvegicus
431305 Gallus gallus
443251 Ovis aries
486551 Canis lupus familiaris
711804 Macaca mulatta
741283 Pan troglodytes
782368 Bos taurus
100008838 Oryctolagus cuniculus
100126278 Sus scrofa
100136906 Equus caballus
100231329 Taeniopygia guttata
100721733 Cavia porcellus
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