anti-ArfGAP with Dual PH Domains 1 (ADAP1) Antibodies

binds inositol(1,3,4,5)tetrakisphosphate (InsP4) and phosphatidylinositol(3,4,5)trisphosphate (PtdInsP3)\;involved in inositol phosphate or inositol lipid signal transduction [RGD, Feb 2006].. Additionally we are shipping ADAP1 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAP1 11033 O75689
ADAP1 231821  
ADAP1 171097  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-ADAP1 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Centa1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Mouse Kidney WB Suggested Anti-Centa1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Mouse Kidney 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185094 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric tissue, using Centaurin alpha 1, antibody at 1:100 dilution. WB Image Sample(30 μg of whole cell lysate) A: A431 , B: HeLaS3 7.5% SDS PAGE antibody diluted at 1:500 100 μL 3 to 4 Days
$466.18
Details
Chicken Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Cerebrum lysate; Primary Ab: 3µg/ml Rabbit Anti-Human CENTa1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 15 to 18 Days
$314.00
Details
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Dog Goat Un-conjugated WB   0.1 mg 4 to 8 Days
$462.00
Details
Human Mouse Un-conjugated ELISA, FACS, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using ADAP1 mAb against human ADAP1 (AA: 240-370) recombinant protein. (Expected MW is 41.6 kDa) 0.1 mg 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using ADAP1 antibody. Western blot analysis of extracts of various cell lines, using ADAP1 antibody (ABIN1870810) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Centaurin alpha 1 Polyclonal Antibody, Unconjugated (ABIN1386169) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$317.90
Details

Top referenced anti-ADAP1 Antibodies

  1. Human Polyclonal ADAP1 Primary Antibody for ELISA, WB - ABIN268683 : Venkateswarlu, Oatey, Tavaré, Jackson, Cullen et al.: Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) ... in The Biochemical journal 1999 (PubMed)

More Antibodies against ADAP1 Interaction Partners

Human ArfGAP with Dual PH Domains 1 (ADAP1) interaction partners

  1. Analyzed ArfGAP with dual PH domains 1 (ADAP1) using mass spectrometry and found that ADAP1 is phosphorylated at Y364.

  2. This review highlights the functions of the neuron-specific protein ADAP1 in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1. [review]

  3. SH-SY5Y cells, stably transfected with GFP-tagged-p42(IP4), show an enhanced NRD protein expression already at an earlier time point after retinoic acid stimulation.

  4. Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-alpha1 (ADAP1).

  5. Full-length KIF13B and CENTA1 form heterotetramers that can bind four phosphoinositide molecules in the vesicle and transport it along the microtubule.

  6. The ARFGAP domain of p42IP4 is involved in the interaction and co-localization with RanBPM protein, without being the only interaction site.

  7. the up-regulated p42(IP4) in Alzheimer's disease neurons may serve as a docking protein to recruit signaling molecules such as different subtypes of casein kinase I to the plasma membrane.

  8. Results show that nucleolin interacts with centaurin-alpha(1) protein, suggesting that centaurin-alpha(1) may be part of a ribonucleoprotein complex.

  9. centaurin-alpha1 negatively regulates ARF6 activity by functioning as an in vivo PIP3-dependent ARF6 GAP

  10. p42IP4 receptor is expressed and distributed throughout the cell in HEK cell lines and is located on chromosome 7, position 7p22.3.

  11. Authors propose alternative concepts of how elevated levels of p42IP4 might relate to its interaction with nucleolin in the pathomechanisms of Alzheimer's disease.

  12. The centaurin, alpha 1 protein is a high-affinity PtdIns(3,4,5)P3-binding protein enriched in brain. Sequence analysis indicates centaurin alpha-1 contains two pleckstrin homology domains, ankyrin repeats and an Arf GAP homology domain.

  13. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2-adrenoceptor internalization.

  14. Centaurin-alpha1 contributes to ERK activation in growth factor signaling, linking the PI3K pathway to the ERK mitogen-activated protein kinase pathway.

  15. Data show that membrane transport of p42(IP4) induced by epidermal growth factor is inhibited by stimulation of phospholipase C-coupled thrombin receptor.

  16. p42IP4 binds to nardilysin via the acidic domain, and that this interaction is controlled by the cognate cellular ligands of p42IP4/centaurin-alpha1

ADAP1 Antigen Profile

Protein Summary

binds inositol(1,3,4,5)tetrakisphosphate (InsP4) and phosphatidylinositol(3,4,5)trisphosphate (PtdInsP3)\;involved in inositol phosphate or inositol lipid signal transduction

Gene names and symbols associated with ADAP1

  • ArfGAP with dual PH domains 1 (ADAP1) antibody
  • ArfGAP with dual PH domains 1 (adap1) antibody
  • ArfGAP with dual PH domains 1 L homeolog (adap1.L) antibody
  • ArfGAP with dual PH domains 1 (Adap1) antibody
  • 4930431P11Rik antibody
  • Centa1 antibody
  • centa2 antibody
  • GC1L antibody
  • GCS1L antibody
  • MGC76109 antibody
  • p42IP4 antibody

Protein level used designations for ADAP1

centaurin, alpha 1 , ArfGAP with dual PH domains 1 , Centaurin-alpha2 protein , arf-GAP with dual PH domain-containing protein 1-like , arf-GAP with dual PH domain-containing protein 1 , inositol(1,3,4,5)tetrakisphosphate receptor , centaurin-alpha , centaurin-alpha-1 , cnt-a1 , putative MAPK-activating protein PM25

GENE ID SPECIES
416451 Gallus gallus
394901 Xenopus (Silurana) tropicalis
495044 Xenopus laevis
696246 Macaca mulatta
750938 Pan troglodytes
100410764 Callithrix jacchus
100472030 Ailuropoda melanoleuca
100558369 Anolis carolinensis
397453 Sus scrofa
11033 Homo sapiens
231821 Mus musculus
606942 Canis lupus familiaris
171097 Rattus norvegicus
282176 Bos taurus
Selected quality suppliers for anti-ADAP1 (ADAP1) Antibodies
Did you look for something else?