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Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Additionally we are shipping Ataxin 1-Like Proteins (2) and many more products for this protein.
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The ATXN1L-CIC-ETS transcription factor axis as a mediator of resistance to MAPKi.
Both ATXN1 and BOAT1 bind to the promoter region of Hey1 and inhibit the transcriptional output of Notch through direct interactions with CBF1, a transcription factor that is crucial for the Notch pathway.
Boat is an in vivo binding partner of ataxin-1 whose altered expression in Purkinje cells may contribute to their degeneration in causes spinocerebellar ataxia type 1 animals
Results provide genetic evidence that the selective neuropathology of Spinocerebellar ataxia type 1 arises from modulation of a core functional activity of ataxin-1
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity).
, brother of ATXN1
, brother of ataxin-1