anti-BCL2-Associated Athanogene (BAG1) Antibodies

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. Additionally we are shipping BAG1 Proteins (18) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BAG1 573 Q99933
BAG1 12017 Q60739
BAG1 297994 B0K019
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Top anti-BAG1 Antibodies at antibodies-online.com

Showing 10 out of 136 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC (p), WB Western blot analysis of Bag1 using anti-Bag1 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat kidney tissue lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Bag1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Bag1 at approximately 39KD. The expected band size for Bag1 is at 39KD. IHC analysis of Bag1 using anti-Bag1 antibody . Bag1 was detected in paraffin-embedded section of mouse testis tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti- Bag1 Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-BAG1 Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole Cell BAG1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, IF, IHC, WB Immunofluorescence of monoclonal antibody to BAG1 on HeLa cell (antibody concentration 35 µg/mL). Western Blot analysis of BAG1 expression in transfected 293T cell line by BAG1 monoclonal antibody (M02), clone 2D3. Lane 1: BAG1 transfected lysate(38.878 KDa). Lane 2: Non-transfected lysate. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Mouse Un-conjugated ELISA, IF, WB Immunofluorescence of monoclonal antibody to BAG1 on HeLa cell (antibody concentration 10 µg/mL). BAG1 monoclonal antibody (M01), clone 4E2 Western Blot analysis of BAG1 expression in HeLa. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-BAG1 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell BAG1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-Bag1 antibody, IHC(P) IHC(P): Rat Intestine Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of BAG1 expression in HEK293T (A), Raw264.7 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of SW620 and mouse kidney cell lines, using BAG1 antibody. 100 μL Log in to see 16 Days
$334.02
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to BAG1 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] BAG1 monoclonal antibody (M02), clone 2D3 Western Blot analysis of BAG1 expression in HeLa . 100 μg Log in to see 11 to 12 Days
$440.00
Details

Top referenced anti-BAG1 Antibodies

  1. Human Polyclonal BAG1 Primary Antibody for WB - ABIN2477577 : Broström, Kronberg, Németh, Oxelbäck: The effect of shoulder muscle training in patients with recurrent shoulder dislocations. in Scandinavian journal of rehabilitation medicine 1992 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal BAG1 Primary Antibody for WB - ABIN2477576 : Liman, Ganesan, Dohm, Krajewski, Reed, Bähr, Wouters, Kermer: Interaction of BAG1 and Hsp70 mediates neuroprotectivity and increases chaperone activity. in Molecular and cellular biology 2005 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal BAG1 Primary Antibody for IHC, IHC (p) - ABIN4282935 : Aust, Pils, Polterauer, Horvat, Cacsire Castillo-Tong, Pils, Dudek, Schmid, Speiser, Reinthaller, Grimm: Expression of Bcl-2 and the antiapoptotic BAG family proteins in ovarian cancer. in Applied immunohistochemistry & molecular morphology : AIMM 2013 (PubMed)

More Antibodies against BAG1 Interaction Partners

Human BCL2-Associated Athanogene (BAG1) interaction partners

  1. Here the authors show that the AF-1 (show EFNA5 Antibodies) domain of AR is bound by the cochaperone Bag-1L.

  2. Over expression of BAG-1 may be a biomarker for cisplatin resistance in patients with primary or recurrent head and neck squamous cell carcinoma.

  3. Increased BAG-1 by PD-L1 (show CD274 Antibodies) confers resistance to tyrosine kinase (show TXK Antibodies) inhibitor in non-small cell lung cancer via persistent activation of ERK (show EPHB2 Antibodies) signaling.

  4. BAG-4/SODD (show BAG4 Antibodies), HSP70 (show HSP70 Antibodies), and HSP90 (show HSP90 Antibodies) are potential prognostic markers in node-negative breast carcinoma that merit further research.

  5. interaction with Bag1 then shifts hERG (show KCNH2 Antibodies) degradation to the membrane-anchored E3 ligase TRC8 (show RNF139 Antibodies) and its E2-conjugating enzyme Ube2g2 (show UBE2G2 Antibodies), as determined by siRNA screening

  6. These results suggest that Bag1 and Bag3 (show BAG3 Antibodies) control the stability of the Hsc70 (show HSPA8 Antibodies)-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 (show HSPA8 Antibodies) system.

  7. Taken together, these data indicate that Bag-1 up-regulation is required to maintain apoptosis resistance in human cytomegalovirus-infected cells.

  8. the combined effects of BAG-1 and XPD (show ERCC2 Antibodies) polymorphisms on chemotherapy sensitivity and survival in patients with advanced non-small-cell lung cancer, which might be the important predictive markers for platinum-based chemotherapy efficacy.

  9. Bag-1 indirectly affects cell survival through c-Myc (show MYC Antibodies) activated signalling that causes elevation of ornithine decarboxylase (show ODC1 Antibodies) levels, leading to an increase of the polyamine content.

  10. Overexpression of miR (show MLXIP Antibodies)-138 inhibited cell proliferation by directly suppressing the expression of Bag-1.

Mouse (Murine) BCL2-Associated Athanogene (BAG1) interaction partners

  1. that BAG-1L over-expression protects against hypoxia/re-oxygenation injury, at least in part, by interacting with HSP70 (show HSP70 Antibodies), and by accelerating the activation of PI3K/AKT (show AKT1 Antibodies) pathways

  2. These studies demonstrate for the first time the significance of BAG-1-mediated protein-protein interactions.

  3. The BAG-1 stabilizes F508del-CFTR by direct binding, probably competing out ubiquitin to partially avoid its proteasomal degradation.

  4. The membrane form of heparin binding EGF-like growth factor (show HBEGF Antibodies) (ProHB-EGF (show EGF Antibodies)) is most likely able to trigger the nuclear translocation of BAG-1 in keeping its level high.

  5. Hemoxygenase (show HMOX1 Antibodies) 1 deficiency provoked diminished Bag-1 level upon LPS (show TLR4 Antibodies) treatment

  6. this study first reported the solution structure of mBAG-1 (show LRRC4 Antibodies)-UBH and the growth factor precursor-interacting motif on the protein.

  7. Bag-1 proteins function as regulators of the action of selective transcription factors.

  8. during development of mouse autopods, BAG-1 expression is downregulated upon the initiation of interdigital apoptosis (BAG-1)

  9. Bag1 is a regulator and marker of neuronal differentiation

  10. BAG1 displays potent neuroprotective activity in vivo against stroke.

BAG1 Antigen Profile

Protein Summary

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Gene names and symbols associated with BAG1

  • BCL2 associated athanogene 1 (BAG1) antibody
  • putative bcl2-associated athanogene (Smp_005900) antibody
  • BCL2-associated athanogene 1 (Bag1) antibody
  • Bcl2 associated athanogene 1 (Bag1) antibody
  • BAG family molecular chaperone regulator 1 (bag-1) antibody
  • BCL-2-associated athanogene 1 (BAG1) antibody
  • BAG family molecular chaperone regulator 1 (LOC781741) antibody
  • BCL2-associated athanogene 1 (bag1) antibody
  • ATBAG1 antibody
  • Bag-1 antibody
  • BCL-2-associated athanogene 1 antibody
  • HAP antibody
  • im:7148830 antibody
  • MSG15.15 antibody
  • MSG15_15 antibody
  • Rap46 antibody
  • si:dkey-216e9.4 antibody

Protein level used designations for BAG1

BAG family molecular chaperone regulator 1 , Bcl-2 associating athanogene-1 protein , Bcl-2-binding protein , glucocortoid receptor-associated protein RAP46 , receptor-associated protein, 46-KD , bcl2-associated athanogene , BCL2-associated athanogene , bcl-2-associated athanogene 1 , hydroxysteroid (17-beta) dehydrogenase 3

GENE ID SPECIES
573 Homo sapiens
8342092 Schistosoma mansoni
100345469 Oryctolagus cuniculus
12017 Mus musculus
297994 Rattus norvegicus
172373 Caenorhabditis elegans
611781 Canis lupus familiaris
835281 Arabidopsis thaliana
781741 Bos taurus
558108 Danio rerio
100513225 Sus scrofa
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