BCL6 Co-Repressor Proteins (BCOR)

The protein encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. Additionally we are shipping BCOR Antibodies (56) and BCOR Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat BCOR BCOR 317346  
BCOR 54880 Q6W2J9
BCOR 71458 Q8CGN4
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Top BCOR Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Escherichia coli (E. coli) Mouse T7 tag,His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days

BCOR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for BCL6 Co-Repressor (BCOR) Interaction Partners

Human BCL6 Co-Repressor (BCOR) interaction partners

  1. Immunohistochemistry for either CCNB3 (show CCNB3 Proteins) or BCOR is not completely sensitive and specific in undifferentiated sarcoma with BCOR-CCNB3 (show CCNB3 Proteins) fusion.

  2. Case Reports: renal sarcomas with BCOR-CCNB3 (show CCNB3 Proteins) gene fusion showing histological overlap with BCOR-related clear cell sarcoma of the kidney.

  3. we report recurrent BCOR exon 16 internal tandem duplications and YWHAE (show YWHAE Proteins)-NUTM2B fusions in half of infantile soft tissue undifferentiated round cell sarcoma and most primitive myxoid mesenchymal tumor of infancy cases, but not in other pediatric sarcomas.

  4. All small blue round cell tumors (SBRCTs) with BCOR-MAML3 and BCOR-CCNB3 (show CCNB3 Proteins) fusions, as well as most with BCOR internal tandem duplications (93%), and all clear cell sarcoma of kidney showed strong and diffuse nuclear BCOR immunoreactivity.

  5. we find that ESS with ZC3H7B-BCOR fusion constitutes a novel type of high-grade endometrial stromal sarcoma and shares significant morphologic overlap with myxoid leiomyosarcoma

  6. We report the case of a 7-month-old girl with atypical oculo-facio-cardio-dental syndrome (OFCD). A novel de novo pathogenic mutation in the BCL6 (show BCL6 Proteins) interacting co-repressor gene (BCOR) (c.4540C>T; p.Arg1514*), was identified on the X chromosome

  7. ZC3H7B-BCOR and MEAF6 (show MEAF6 Proteins)-PHF1 (show PHF1 Proteins) fusions occurred predominantly in S100 protein-negative and malignant ossifying fibromyxoid tumors.

  8. Given the high frequency and pattern of aberration, BCOR is likely to play an important role in ENKTL pathogenesis as a tumor suppressor gene

  9. Data suggest the detection of the partial duplication inside exon 15 of proto-oncogene (show RAB1A Proteins) protein BCOR as part of the diagnostic process of pediatric kidney tumors.

  10. Report mutually exclusive BCOR internal tandem duplications and YWHAE (show YWHAE Proteins)-NUTM2 fusions in clear cell sarcoma of kidney.

Mouse (Murine) BCL6 Co-Repressor (BCOR) interaction partners

  1. results provide the first evidence of a tumor suppressor role for BCOR in the pathogenesis of T lymphocyte malignancies

  2. Data show that BCL6 interacting corepressor Bcor Is Specifically Down-regulated by Activin Signaling in trophoblast stem cells (TSCs).

  3. T cell-expressed BCOR is critical for optimal GC-Tfh cell differentiation and humoral immunity.

  4. IRF8 (show IRF8 Proteins) pairs with BCL6 co-repressor BCOR in the nucleus to enhance its transcriptional repressive activity.

  5. Results suggest that Bcor expressed in the mesenchyme plays crucial roles during early tooth development.

  6. Study isolated an Fbxl10/Jhdm1B (show KDM2B Proteins) complex by Study using a high throughput proteomics approach identified interactors with Rnf2 (show RNF2 Proteins) including Fbxl10/Jhdm1B (show KDM2B Proteins), casein kinase subunits, and the BcoR corepressor

  7. Bcor plays a role in differentiation of multiple tissue lineages during early embryonic development.

BCOR Protein Profile

Protein Summary

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.

Gene names and symbols associated with BCL6 Co-Repressor Proteins (BCOR)

  • BCL6 corepressor (bcor)
  • BCL6 corepressor (BCOR)
  • BCL-6 corepressor (LOC541088)
  • BCL6 co-repressor (Bcor)
  • BCL6 interacting corepressor (Bcor)
  • 5830466J11Rik protein
  • 8430401K06Rik protein
  • ANOP2 protein
  • BCOR protein
  • BcorR protein
  • D930024N20Rik protein
  • MAA2 protein
  • MCOPS2 protein
  • mKIAA1575 protein
  • RGD1562735 protein

Protein level used designations for BCL6 Co-Repressor Proteins (BCOR)

BCL-6 corepressor , BCL6 co-repressor , BCL-6 interacting corepressor , Bcl6 interacting corepressor

402921 Danio rerio
418574 Gallus gallus
465574 Pan troglodytes
541088 Bos taurus
698644 Macaca mulatta
100050335 Equus caballus
317346 Rattus norvegicus
784529 Bos taurus
54880 Homo sapiens
480880 Canis lupus familiaris
71458 Mus musculus
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