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The C-terminus of the protein encoded by BTBD2 binds topoisomerase I. Additionally we are shipping BTBD2 Proteins (2) and many more products for this protein.
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Interaction of BTBD1 (show BTBD1 Antibodies) and BTBD2 with TOP1 (show TOP1 Antibodies) requires TOP1 (show TOP1 Antibodies) residues 236 and 237, the same residues required to enhance the infectivity of progeny virions when TOP1 (show TOP1 Antibodies) is expressed in African Green Monkey producer cells.
Polymorphisms in the LIG4 (show LIG4 Antibodies), BTBD2, HMGA2, and RTEL1 (show RTEL1 Antibodies) genes, which are involved in the double-strand break repair pathway, are associated with glioblastoma multiforme survival.
subcellular colocalization of BTBD1 (show BTBD1 Antibodies) and BTBD2 to cytoplasmic bodies; TRIM5delta colocalized with BTBD1 (show BTBD1 Antibodies)/2 and appeared to serve as a scaffold for the assembly of endogenous BTBD1 (show BTBD1 Antibodies)/2 proteins
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies.
BTB (POZ) domain-containing protein 2
, BTB (POZ) domain containing 2
, BTB (POZ) domain containing 2-like
, BTB/POZ domain-containing protein 2-like
, BTB domain protein 2
, BTB/POZ domain-containing protein 2