Basonuclin 1 Proteins (BNC1)

The protein encoded by BNC1 is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. Additionally we are shipping Basonuclin 1 Antibodies (48) and Basonuclin 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BNC1 646 Q01954
BNC1 12173  
Rat BNC1 BNC1 365299  
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Top Basonuclin 1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$340.00
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human BNC1 Protein. 100 μg 11 to 18 Days
$639.61
Details

BNC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Basonuclin 1 (BNC1) Interaction Partners

Human Basonuclin 1 (BNC1) interaction partners

  1. A female mouse model of the human Bnc1 frameshift mutation exhibited infertility, significantly increased serum follicle-stimulating hormone, decreased ovary size and reduced follicle numbers, consistent with primary ovarian insufficiency (POI). Haploinsufficiency of BNC1 as an etiology of human autosomal dominant POI was reported.

  2. Study shows that BNC1 expression was down-regulated in hepatocellular tumors and cell lines through its promotor hypermethylation.

  3. Study demonstrates that Bnc1 regulates epithelial plasticity of mammary epithelial cells and influences outcome of TGF-beta1 signaling.

  4. p63 induces the expression of the basal epithelial transcription factor, Basonuclin 1.

  5. Data show that basonuclin (Bn)2 but not bn1 colocalizes with SC35 in nuclear speckles, and may have a function in nuclear processing of mRNA.

Mouse (Murine) Basonuclin 1 (BNC1) interaction partners

  1. A female mouse model of the human Bnc1 frameshift mutation exhibited infertility, significantly increased serum follicle-stimulating hormone, decreased ovary size and reduced follicle numbers, consistent with primary ovarian insufficiency.

  2. BNC1 cannot substitute for BNC2.

  3. HSF2BP may play a pivotal role in regulating BNC1 transcriptional activity and subcellular localization during spermatogenesis.

  4. BNC1 is required for the maintenance of spermatogenesis.

  5. Basonuclin likely coordinates functions of a subset of ribosomal RNA genes (rDNA) and a group of protein coding genes in cellular processes critical for the regulation of cell proliferation

Basonuclin 1 (BNC1) Protein Profile

Protein Summary

The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. This gene seems to have multiple alternatively spliced transcript variants, but their full-length nature is not known yet. There seems to be evidence of multiple polyadenylation sites for this gene.

Gene names and symbols associated with Basonuclin 1 Proteins (BNC1)

  • basonuclin 1 (BNC1)
  • basonuclin 1 (bnc1)
  • basonuclin 1 (Bnc1)
  • AI047752 protein
  • AW546376 protein
  • Bnc protein
  • BSN1 protein
  • fc51b07 protein
  • HsT19447 protein
  • wu:fc51b07 protein

Protein level used designations for Basonuclin 1 Proteins (BNC1)

zinc finger protein basonuclin-1 , basonuclin 1 , zinc finger protein basonuclin-1-like , zinc finger protein basonuclin

GENE ID SPECIES
488756 Canis lupus familiaris
524182 Bos taurus
325002 Danio rerio
427504 Gallus gallus
467745 Pan troglodytes
718655 Macaca mulatta
100398841 Callithrix jacchus
100466760 Ailuropoda melanoleuca
100492394 Xenopus (Silurana) tropicalis
100548200 Meleagris gallopavo
100562714 Anolis carolinensis
100603092 Nomascus leucogenys
646 Homo sapiens
12173 Mus musculus
365299 Rattus norvegicus
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