anti-Beaded Filament Structural Protein 2, Phakinin (BFSP2) Antibodies

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Additionally we are shipping BFSP2 Proteins (4) and BFSP2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BFSP2 8419 Q13515
BFSP2 107993 Q6NVD9
BFSP2 501046  
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Top anti-BFSP2 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-BFSP2 Antibody Titration: 1.0 ug/ml Positive Control: 293T Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemistry: phakinin Antibody (4E7) [NBP2-46573] - Analysis of Adenocarcinoma of Human ovary tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Immunohistochemistry: phakinin Antibody (4E7) [NBP2-46573] - Analysis of Carcinoma of Human liver tissue.(Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: phakinin Antibody [NBP1-90621] - Staining of human lateral ventricle shows weak cytoplasmic positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: phakinin Antibody [NBP1-90621] Staining of human cell line A-431 shows positivity in plasma membrane & cytoplasm. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Antigen: 0.2ug/100ul, Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in MicroplateReader by 450nm 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Mouse Un-conjugated IHC (p), WB   100 μL Log in to see 7 to 9 Days
$507.83
Details
Cow Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

BFSP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against BFSP2 Interaction Partners

Human Beaded Filament Structural Protein 2, Phakinin (BFSP2) interaction partners

  1. The results suggest that the N-terminal domain of CRYAA (show CRYAA Antibodies) is required during in vitro complex formation with filensin (show BFSP1 Antibodies) and phakinin.

  2. We report a novel mutation (p.G112E) in the BFSP2 gene, underscoring the physiological importance of the beaded filament protein and supporting its role in human cataract formation.

  3. Data show that BFSP2 and PITX3 (show PITX3 Antibodies), hitherto known to cause eye defects only in a dominant fashion, can also present recessively.

  4. The Y-sutural opacity in the lens might be the typical and earliest sign for cataract caused by the BFSP2 mutation. In addition, a myopia susceptibility locus in this region, which might also be associated with the mutation in BFSP2.

  5. Progressive isolated sutural cataract associated with deletion mutation of BFSP2 gene in Chinese pedigree. Physiological importance of beaded filament protein. Role of BFSP2 in human cataract formation.

  6. Progressive phenotype has provided more evidence for the heterogeneity of congenital cataract caused by BFSP2 mutations and for the important role BFSP2 plays in cataract formation.

  7. This is the first reported case of a congenital lamellar cataract phenotype associated with the mutation of Arg339His (P.R339H) in BFSP2.

Mouse (Murine) Beaded Filament Structural Protein 2, Phakinin (BFSP2) interaction partners

  1. CP49 and filensin (show BFSP1 Antibodies) have been considered robust markers for mouse lens fiber cell differentiation. The data reported here, however, document both proteins in the mouse lens epithelium, but only after 5 weeks of age, when lens epithelial growth and mitotic activity have slowed.

  2. CP49 is involved in a functional synergy critical for regulating lens fiber cell geometry, transparency, and mechanical stiffness.

  3. disruption of the Hsf4 (show HSF4 Antibodies) gene leads to cataracts via at least three pathways: down-regulation of gamma-crystallin, particularly gamma S-crystallin (show CRYGS Antibodies); decreased lens beaded filament expression; and loss of post-translational modification of alpha A-crystallin (show CRYAA Antibodies)

Zebrafish Beaded Filament Structural Protein 2, Phakinin (BFSP2) interaction partners

BFSP2 Antigen Profile

Protein Summary

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

Gene names and symbols associated with BFSP2

  • beaded filament structural protein 2 (BFSP2) antibody
  • beaded filament structural protein 2, phakinin (Bfsp2) antibody
  • beaded filament structural protein 2 (Bfsp2) antibody
  • beaded filament structural protein 2, phakinin (bfsp2) antibody
  • AI448593 antibody
  • Bfsp2 antibody
  • CP47 antibody
  • CP49 antibody
  • CP49INS antibody
  • CTRCT12 antibody
  • LIFL-L antibody
  • LOC100222605 antibody
  • PHAKOSIN antibody
  • zgc:103750 antibody

Protein level used designations for BFSP2

49 kDa cytoskeletal protein , beaded filament protein CP49 , bfps2, Cytoskeletal protein, 49-kD , lens fiber cell beaded filament protein CP 47 , lens fiber cell beaded filament protein CP 49 , lens intermediate filament-like light , phakinin , CP 47 , CP47 , CP49 , beaded filament structural protein 2, phakinin , cytoskeletal protein CP 49 , phakinin-like , DKEYP-73D8.2

GENE ID SPECIES
8419 Homo sapiens
107993 Mus musculus
281645 Bos taurus
396141 Gallus gallus
460708 Pan troglodytes
608938 Canis lupus familiaris
100101576 Oryctolagus cuniculus
100222605 Taeniopygia guttata
100306969 Cavia porcellus
100404357 Callithrix jacchus
100441274 Pongo abelii
100594242 Nomascus leucogenys
501046 Rattus norvegicus
494090 Danio rerio
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