BCAR3 Proteins

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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5 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3089928
$13,376.85
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 70 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3130609
$13,376.85
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 70 Business Days
ReactivityHuman
Application AA, AP, ELISA, WB
Order details Cat. No. ABIN1346502
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity ≥ 90 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN4990598
$716.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2715176
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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BCAR3 Protein Profile

Protein Summary

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BCAR3

  • breast cancer anti-estrogen resistance 3 (BCAR3) antibody
  • breast cancer anti-estrogen resistance 3 (Bcar3) antibody
  • breast cancer anti-estrogen resistance 3 (bcar3) antibody
  • breast cancer anti-estrogen resistance 3 L homeolog (bcar3.L) antibody
  • AI131758 antibody
  • AND-34 antibody
  • BCAR3 antibody
  • NSP2 antibody
  • SH2D3B antibody

Protein level used designations for BCAR3

SH2 domain-containing protein 3B , breast cancer anti-estrogen resistance protein 3 , breast cancer antiestrogen resistance 3 protein , dJ1033H22.2 (breast cancer anti-estrogen resistance 3) , novel SH2-containing protein 2 , p130Cas-binding protein AND-34 , breast cancer anti-estrogen resistance 3 , breast cancer antiestrogen resistance 3 , breast cancer anti-estrogen resistance protein 3-like

GENE ID SPECIES
8412 Homo sapiens
29815 Mus musculus
310838 Rattus norvegicus
424494 Gallus gallus
457032 Pan troglodytes
479941 Canis lupus familiaris
506231 Bos taurus
570610 Danio rerio
100059015 Equus caballus
100404661 Callithrix jacchus
100447373 Pongo abelii
100219682 Taeniopygia guttata
100029255 Monodelphis domestica
100155981 Sus scrofa
100352424 Oryctolagus cuniculus
100475875 Ailuropoda melanoleuca
100036719 Xenopus (Silurana) tropicalis
100593533 Nomascus leucogenys
432292 Xenopus laevis
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