anti-CD63 Molecule (CD63) Antibodies

The protein encoded by CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping CD63 Kits (41) and CD63 Proteins (22) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD63 12512 P41731
CD63 967 P08962
CD63 29186 P28648
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Top anti-CD63 Antibodies at antibodies-online.com

Showing 10 out of 630 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
REACT_Bird Goat Un-conjugated IF, WB 600 μg Log in to see 5 to 7 Days
$544.43
Details
Dog Mouse Un-conjugated DB, ELISA, EM, FACS, Func, ICC, IF, IP, WB Flow Cytometry: CD63 Antibody (H5C6) [NBP2-42225] - A431 cells were stained (1 x10^6 cells/ml) using the anti-CD63 antibody at a 1:1000 dilution (blue). Signal was detected with Gt x Ms Dylight 488 secondary. Isotype shown in orange. Flow Cytometry: CD63 Antibody (H5C6) [NBP2-42225] - Human peripheral blood cells were stained (2 x 10^6 cells/ml) using the anti-CD63 antibody (blue) at a dilution of 1:1000. Signal was detected using a Gt x Ms Dylight 488 Secondary and gated to the monocyte/granulocyte cell populations. Isotype was Mouse IgG1 kappa (orange). Data collected on BD FACS Calibur flow cytometer. 0.1 mL Log in to see 7 to 9 Days
$446.35
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- CD63 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti- CD63 Picoband antibody, Western blotting All lanes: Anti CD63  at 0.5ug/ml WB: Recombinant Human CD63 Protein 0.5ng Predicted bind size: 26KD Observed bind size: 26KD 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Mouse Un-conjugated CyTOF, FACS, ICC, IF, IHC, IHC (p), IP, WB Flow Cytometry: CD63 Antibody (MEM-259) [ABIN2628373] - Analysis using the FITC conjugate of ABIN2628373. Staining of peripheral blood lymphocytes from a patient with allergy to bee venom after stimulation with bee venom, stained with anti-human CD63 (MEM-259) FITC. 0.1 mg Log in to see 12 to 15 Days
$446.35
Details
Human Rabbit Un-conjugated WB Sample Type: OVCAR3 cell lysateAntibody Titration: 1.0 ug/mlGel concentration: 12% Sample Type: mouse fibroblast lusate (20ug)Primary Dilution: 1:800 (2% milk)Secondary Dilution: 1:2000 (5% milk)Image Submitted By: Anonymous researcher . 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CD63 Antibody (C-term) (ABIN651526) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the CD63 antibody detected the CD63 protein (arrow). CD63 Antibody (C-term) (ABIN651526) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 200 μL Log in to see 10 to 11 Days
$385.00
Details
Human Mouse Biotin FACS, ICC, IHC (p), IP Immunofluorescence staining of human skin fibroblasts with anti-CD63 (MEM-259 ; green) after co-incubation of living cells with human Transferrin - Dyomics 547 (red); cell nuclei stained with DAPI (blue). Fig. 2. Immunofluorescence staining of CD63 in human primary fibroblasts using anti-CD63 (; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue). Fig. 3. Immunofluorescence staining of CD63 in human HeLa cell line using anti-CD63 (Fig. 4. Flow cytometry analysis of peripheral blood lymphocytes from a patient with allergy to bee venom after stimulation with bee venom, stained with anti-human CD63 () FITC. Immunofluorescence staining of human skin fibroblasts with anti-CD63 (MEM-259 ; green) after co-incubation of living cells with human Transferrin - Dyomics 547; cell nuclei stained with DAPI (blue). 0.1 mg Log in to see 5 to 7 Days
$428.84
Details
Human Mouse FITC FACS, ICC, IHC (p), IP Immunofluorescence staining of human skin fibroblasts with anti-CD63 (MEM-259 ; green) after co-incubation of living cells with human Transferrin - Dyomics 547 (red); cell nuclei stained with DAPI (blue). Fig. 2. Immunofluorescence staining of CD63 in human primary fibroblasts using anti-CD63 (; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue). Fig. 3. Immunofluorescence staining of CD63 in human HeLa cell line using anti-CD63 (Fig. 4. Flow cytometry analysis of peripheral blood lymphocytes from a patient with allergy to bee venom after stimulation with bee venom, stained with anti-human CD63 () FITC. Immunofluorescence staining of human skin fibroblasts with anti-CD63 (MEM-259 ; green) after co-incubation of living cells with human Transferrin - Dyomics 547; cell nuclei stained with DAPI (blue). 100 Tests Log in to see 5 to 7 Days
$428.84
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using CD63 Antibody. Immunohistochemistry of paraffin-embedded rat brain using CD63 antibody. 100 μL Log in to see 13 to 14 Days
$393.25
Details
Human Mouse APC FACS, ICC, IHC (p), IP Immunofluorescence staining of human skin fibroblasts with anti-CD63 (MEM-259 ; green) after co-incubation of living cells with human Transferrin - Dyomics 547 (red); cell nuclei stained with DAPI (blue). Fig. 2. Immunofluorescence staining of CD63 in human primary fibroblasts using anti-CD63 (; green). Actin cytoskeleton was decorated by phalloidin (red) and cell nuclei stained with DAPI (blue). Fig. 3. Immunofluorescence staining of CD63 in human HeLa cell line using anti-CD63 (Fig. 4. Flow cytometry analysis of peripheral blood lymphocytes from a patient with allergy to bee venom after stimulation with bee venom, stained with anti-human CD63 () FITC. Immunofluorescence staining of human skin fibroblasts with anti-CD63 (MEM-259 ; green) after co-incubation of living cells with human Transferrin - Dyomics 547; cell nuclei stained with DAPI (blue). 100 Tests Log in to see 5 to 7 Days
$497.45
Details

Top referenced anti-CD63 Antibodies

  1. Dog (Canine) Monoclonal CD63 Primary Antibody for DB, ELISA - ABIN4295280 : Azorsa, Moog, Cazenave, Lanza: A general approach to the generation of monoclonal antibodies against members of the tetraspanin superfamily using recombinant GST fusion proteins. in Journal of immunological methods 1999 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal CD63 Primary Antibody for CyTOF, FACS - ABIN262837 : Chow, Zhou, Liu, Fong, Champer, Van Haute, Chin, Ren, Gugiu, Meng, Huang, Ngo, Kortylewski, Wang: Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB. in Scientific reports 2014 (PubMed)
    Show all 5 Pubmed References

  3. Bird (Avian) Polyclonal CD63 Primary Antibody for IF, WB - ABIN1440014 : Huang, Isobe, Yoshimura: Changes in localization and density of CD63-positive exosome-like substances in the hen oviduct with artificial insemination and their effect on sperm viability. in Theriogenology 2018 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal CD63 Primary Antibody for FACS, IF (p) - ABIN687742 : Son, Rahimian, Shin, Siltanen, Patel, Revzin: Microfluidic compartments with sensing microbeads for dynamic monitoring of cytokine and exosome release from single cells. in The Analyst 2015 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal CD63 Primary Antibody for FACS - ABIN2472275 : Tusie-Luna, Traktman, White: Determination of functional effects of mutations in the steroid 21-hydroxylase gene (CYP21) using recombinant vaccinia virus. in The Journal of biological chemistry 1991 (PubMed)
    Show all 4 Pubmed References

  6. Cow (Bovine) Monoclonal CD63 Primary Antibody for FACS - ABIN2472271 : Peschle, Migliaccio, Migliaccio, Mavilio, Rocca, Petrini, Mastroberardino, Comi, Giglioni, Ottolenghi: A model for hemoglobin F synthesis in adult life: evidence for regulation at the level of erythroblasts. in Annals of the New York Academy of Sciences 1985 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal CD63 Primary Antibody for FACS, IF - ABIN2472272 : Abdel-Latif, Steward, Macdonald, Francis, Dinauer, Lacy: Rac2 is critical for neutrophil primary granule exocytosis. in Blood 2004 (PubMed)
    Show all 4 Pubmed References

  8. Human Monoclonal CD63 Primary Antibody for FACS - ABIN2472276 : Casey, Meade, Hewitt: Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome. in Molecular & cellular proteomics : MCP 2007 (PubMed)
    Show all 4 Pubmed References

  9. Human Monoclonal CD63 Primary Antibody for FACS, IF - ABIN536030 : Kwon, Shin, Yim, Lee, Kang, Kim, Chung: CD63 as a biomarker for predicting the clinical outcomes in adenocarcinoma of lung. in Lung cancer (Amsterdam, Netherlands) 2007 (PubMed)
    Show all 3 Pubmed References

  10. Human Monoclonal CD63 Primary Antibody for FACS, IF - ABIN536031 : Cerny, Feng, Yu, Miyake, Borgonovo, Klumperman, Meldolesi, McNeil, Kirchhausen: The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. in EMBO reports 2004 (PubMed)
    Show all 3 Pubmed References

More Antibodies against CD63 Interaction Partners

Mouse (Murine) CD63 Molecule (CD63) interaction partners

  1. In renal proximal tubules, CD63 determines the insertion of OCT2 into the proper membrane domain and mediates transporter regulation by trafficking processes.

  2. TIMP1 signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  3. The Muted protein is important for the steady-state level of CD63.

  4. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.

  5. These findings identify CD63 as an important component of allergic inflammation.

  6. CD63 serves to bridge between beta1 integrin and VEGFR2 because CD63 silencing disrupted VEGFR2-beta1 integrin complex formation identified using proximity ligation assay

  7. Loss of CD63 is associated impairment of amyloidogenesis and downstream melanosome morphogenesis.

  8. Loss of CD63 has a similar phenotype to loss of P-selectin itself, thus CD63 is an essential cofactor to P-selectin.

  9. CXCR4 can be downregulated on activated B cells by IL-21-induced endocytosis and CD63-mediated endosomal recruitment.

  10. The findings identify palmitoylation-dependent association with the tetraspanin CD63 as the mechanism by which Syt VII is targeted to lysosomes.

  11. CD63, but not RILP, is recruited to the phagosomes in macrophages expressing the dominant negative form of Rab7.

  12. CD63 is recruited to already-budded Weibel-Palade bodies by an AP-3-dependent route

  13. Upon phagocytosis of Cryptococcus neoformans and polystyrene beads, CD63 was recruited selectively to C. neoformans-containing phagosomes in a MyD88-independent acidification-dependent manner

  14. protein region defined by amino acid residues 103-205 for CD63 interacts with amelogenin

  15. CD63 knockout mice show an increased urinary flow, water intake, reduced urine osmolality, and a higher fecal water content.

  16. the activation-induced degranulation of Fas ligand has distinct requirements and involves different mechanisms than those of the granule markers CD63 and CD107a/Lamp-1

Human CD63 Molecule (CD63) interaction partners

  1. findings suggest that the CD63 gene may be involved in the pathogenesis of endometriosis, since they participate in mechanisms such as inhibition of apoptosis, angiogenesis and cell proliferation, which lead to the loss of cell homeostasis in the ectopic endometrium, thus contributing to the implantation and survival of the tissue in the extrauterine environment

  2. Signaling focal contacts via CD63 were identified to facilitate cell adhesion, migration and mediate extracellular matrix-physical cues to modulate hematopoietic stem cells and progenitor cells function.

  3. Human CD63-GFP expression was controlled under the rat Sox2 promoter (Sox2/human CD63-GFP), and it was expressed in undifferentiated fetal brains.

  4. our results identify the CD63-syntenin-1-ALIX complex as a key regulatory component in post-endocytic HPV trafficking.

  5. Exosomal markers CD63 and CD9 are elevated in pancreatic tumor tissues.

  6. CD63 and exosome expression is altered in scleroderma dermal fibroblasts

  7. CD63 is a critical player in LMP1 exosomal trafficking and LMP1-mediated enhancement of exosome production and may play further roles in limiting downstream LMP1 signaling.

  8. TIMP1 signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  9. Concentrations of Cd63 were elevated in gingival crevicular fluid of patients with pre-eclampsia.

  10. CD163(+) TAMs in oral premalignant lesions coexpress CD163 and STAT1, suggesting that the TAMs in oral premalignant lesions possess an M1 phenotype in a Th1-dominated micromilieu.

  11. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63.

  12. These findings indicate that rhTIMP-1 promotes clonogenic expansion and survival in human progenitors via the activation of the CD63/PI3K/pAkt signaling pathway

  13. It was shown that treatment of macrophages with anti-CD63 inhibits CCR5-mediated virus infection in a cell type-specific manner, but that no inhibition of CXCR4-tropic viruses occurs.

  14. TM4SF5 interacted with CD151, and caused the internalization of CD63 from the cell surface.

  15. Diesel exhaust exposure during exercise induces platelet activation as illustrated by a dose-response increase in the release of CD62P and CD63.

  16. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity.

  17. CD63 tetraspanin is a negative driver of epithelial-to-mesenchymal transition in human melanoma cells.

  18. these results indicated that high glycosylation of CD63 by RPN2 is implicated in clinical outcomes in breast cancer patients

  19. CD9 and CD63 tetraspanins block HIV-1-induced cell-cell fusion at the transition from hemifusion to pore opening.

  20. Collectively, these findings indicate that CD63 may support Env-mediated fusion as well as a late (post-integration) step in the HIV-1 replication cycle.

CD63 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Gene names and symbols associated with anti-CD63 Molecule (CD63) Antibodies

  • CD63 antigen (Cd63) antibody
  • CD63 molecule (CD63) antibody
  • Cd63 molecule (Cd63) antibody
  • CD63 molecule (Cd63) antibody
  • C75951 antibody
  • LAMP-3 antibody
  • ME491 antibody
  • MLA1 antibody
  • OMA81H antibody
  • TSP29FA antibody
  • TSPAN30 antibody

Protein level used designations for anti-CD63 Molecule (CD63) Antibodies

melanoma 1 antigen , CD63 antigen , CD63 antigen (melanoma 1 antigen) , granulophysin , lysosomal-associated membrane protein 3 , lysosome-associated membrane glycoprotein 3 , melanoma-associated antigen ME491 , melanoma-associated antigen MLA1 , ocular melanoma-associated antigen , tetraspanin-30 , tspan-30 , ME491/CD63 antigen , mast cell antigen AD1

GENE ID SPECIES
12512 Mus musculus
100155929 Sus scrofa
100051450 Equus caballus
967 Homo sapiens
404156 Bos taurus
493846 Felis catus
100008988 Oryctolagus cuniculus
29186 Rattus norvegicus
474391 Canis lupus familiaris
101114944 Ovis aries
100716198 Cavia porcellus
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