CD99 Proteins (CD99)

The protein encoded by CD99 is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. Additionally we are shipping CD99 Antibodies (441) and CD99 Kits (31) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD99 673094 Q8VCN6
CD99 4267 P14209
CD99 652929  
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Top CD99 Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$280.50
Details
HEK-293 Cells Human Fc Tag Human CD99, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. 100 μg Log in to see 2 to 3 Days
$319.00
Details
Human Cells Mouse Fc Tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HEK-293 Cells Human His tag Validation with Western Blot 10 μg Log in to see 12 to 15 Days
$378.24
Details
Human Cells Rat Fc Tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
$654.29
Details
HEK-293 Cells Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
$584.38
Details

CD99 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, , ,
Human , , , , ,
, , , , ,
Rat (Rattus) ,
,

More Proteins for CD99 Interaction Partners

Mouse (Murine) CD99 interaction partners

  1. endothelial CD99 promotes leukocyte attachment to endothelium in inflamed vessels by a heterophilic ligand. In addition, CD99 binds to PILRs on neutrophils, an interaction that leads to increased shear resistance of the neutrophil attachment to ICAM-1 (show ICAM1 Proteins).

  2. Endothelial CD99 signals through soluble adenylyl cyclase (show ADCY10 Proteins) and PKA to regulate leukocyte transendothelial migration.

  3. role in membrane trafficking of CD99L2 (show CD99L2 Proteins) and in controlling transendothelial migration of leukocytes

  4. CD99 plays a crucial role in the attenuation of graft-versus-host disease by regulating the expansion of myeloid-derived suppressor cells.

  5. CD99L2 (show CD99L2 Proteins) and CD99 are involved in transendothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum

  6. These findings indicate that sialylated O-linked sugar structures on CD99 play an important role in the recognition of PILR.

  7. Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein receptor (show LDLR Proteins)-deficient mice.

  8. Mouse CD99 is expressed on mouse leukocytes as well as enriched at the endothelial cell borders.

Human CD99 interaction partners

  1. Besides confirming the importance of CD99, findings indicate that polymorphic variations in this gene may affect either development or progression of EWS (show EWSR1 Proteins).

  2. CD99 is a marker of acute myeloid leukemia (show BCL11A Proteins) and myelodysplastic syndrome stem cells

  3. CD99 expression is increased in patients with active Inflammatory bowel disease, and positively correlated with disease activity.

  4. CD99 counteracts EWS (show EWSR1 Proteins)-FLI1 (show FLI1 Proteins) in controlling NF-kappaB (show NFKB1 Proteins) signaling through the miR (show MLXIP Proteins)-34a, which is increased and secreted into exosomes released by CD99-silenced Ewing sarcoma cells.

  5. these observations suggest that CD99 is involved in the regulation of CD1a (show CD1A Proteins) transcription and expression by increasing ATF-2 (show ATF2 Proteins).

  6. CD99 was also paranuclear positive in 4 of 11 (36%) small cell lung carcinomas

  7. Data show that CD99 antigen expression increased during in vitro differentiation of germinal center B cells and was highest in plasma cells (PCs).

  8. Our results suggest that the CD34 (show CD34 Proteins)/CD25 (show IL2RA Proteins)/CD123 (show IL3RA Proteins)/CD99(+) LAIP is strictly associated with FLT3 (show FLT3 Proteins)-ITD-positive cells.

  9. These results suggest that SEPTIN2-mediated cytoskeletal rearrangement and STATHMIN (show STMN1 Proteins)-mediated differentiation may contribute to changes in cell morphology and differentiation of H/RS cells with CD99 upregulation in Hodgkin lymphoma.

  10. The results highlight an important role of CD99 in the differentiation and activity of human osteoblasts in physiological and pathological conditions.

CD99 Protein Profile

Protein Summary

The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD99 Proteins (CD99)

  • CD99 antigen (Cd99)
  • CD99 molecule (Xg blood group) (CD99)
  • CD99 molecule (Xg blood group) (Cd99)
  • CD99 molecule (CD99)
  • 1110061M03Rik protein
  • 2410026K10Rik protein
  • D4 protein
  • HBA71 protein
  • MIC2 protein
  • MIC2X protein
  • MIC2Y protein
  • MSK5X protein
  • pilr-1 protein
  • Pilr-l protein

Protein level used designations for CD99 Proteins (CD99)

paired immunoglobin-like type 2 receptor-ligand , CD99 antigen , E2 antigen , MIC2 (monoclonal antibody 12E7) , T-cell surface glycoprotein E2 , antigen identified by monoclonal 12E7, Y homolog , antigen identified by monoclonal antibodies 12E7, F21 and O13 , surface antigen MIC2

GENE ID SPECIES
673094 Mus musculus
4267 Homo sapiens
652929 Rattus norvegicus
418662 Gallus gallus
101115513 Ovis aries
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