This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
Gene names and symbols associated with Cadherin 20 Proteins (CDH20)
cadherin 20 (Cdh20) antibody
cadherin 20 L homeolog (cdh20.L) antibody
cadherin 20 (CDH20) antibody
cadherin 20, type 2 (CDH20) antibody
Protein level used designations for Cadherin 20 Proteins (CDH20)