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Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction..
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Human Polyclonal CAPN1 Primary Antibody for IF (cc), IF (p) - ABIN737646
Miners, Renfrew, Swirski, Love: Accumulation of ¿-synuclein in dementia with Lewy bodies is associated with decline in the ¿-synuclein-degrading enzymes kallikrein-6 and calpain-1. in Acta neuropathologica communications 2014
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Human Polyclonal CAPN1 Primary Antibody for IHC (p), WB - ABIN965738
Imajoh, Aoki, Ohno, Emori, Kawasaki, Sugihara, Suzuki: Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease. in Biochemistry 1989
Cow (Bovine) Monoclonal CAPN1 Primary Antibody for ICC, IHC (fro) - ABIN267206
Viringipurampeer, Shan, Gregory-Evans, Zhang, Mohammadi, Gregory-Evans: Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish. in Cell death and differentiation 2014
Cow (Bovine) Polyclonal CAPN1 Primary Antibody for WB - ABIN222978
Jayanthi, Deng, Noailles, Ladenheim, Cadet: Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004
Cow (Bovine) Polyclonal CAPN1 Primary Antibody for ELISA, IHC - ABIN1582151
Li, Shi, Han, Wang, Yang, Cao, Jiao: Effects of ARHI on cell cycle progression and apoptosis levels of breast cancer cells. in Tumour biology 2012
A total of 55 genes were differentially expressed in micro-calpain knockout mice.
calpains inhibition plays crucial roles in vascular restenosis by preventing neointimal hyperplasia at the early stage via suppression of the MMP2 (show MMP2 Antibodies)/TGF-beta1 (show TGFB1 Antibodies) pathway.
indicate that calpain-1 and calpain-2 (show CAPN2 Antibodies) play opposite roles in high increased intraocular pressure-induced ischemic injury
Results strengthen the roles of both calpain-1 and PHLPP1 (show PHLPP1 Antibodies) in synaptic plasticity and learning and memory, and illustrate the complexities of the interactions between multiple pathways participating in synaptic plasticity.
Genetic ablation of calpain-1 ameliorates chronic pain behavior in sickle cell mice.
Our results indicate that calpain mediates cytokine-induced collagen-I synthesis and proliferation of ASMCs via the mTORC2 (show CRTC2 Antibodies)/Akt (show AKT1 Antibodies) signalling pathway, thereby regulating airway smooth muscle remodelling in asthma.
mutations in CAPN1 are an additional cause of ataxia in mammals, including humans.
Results indicate that calpain-1 and calpain-2 (show CAPN2 Antibodies) are differentially activated in hippocampus following seizure activity, with calpain-1 activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 (show CAPN2 Antibodies) is widely activated in pyramidal neurons of CA1 (show CA1 Antibodies) and CA3 (show CA3 Antibodies), and triggers neurodegenerative cascades.
Here we show the combined loss of glial glutamate (show GRIN1 Antibodies) transporters GLT1 (show SLC1A2 Antibodies) and GLAST (show SLC1A3 Antibodies) in spinal cord caused motor neuronal death and hindlimb paralysis.
These results suggested that Streptococcus pneuomoniae PLY induces the influx of calcium in Streptococcus pneumoniae-infected macrophages, followed by calpain activation and subsequent IL-1alpha maturation and secretion.
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
calpain 1, large subunit
, CANP 1
, calcium-activated neutral proteinase 1
, calpain mu-type
, calpain-1 catalytic subunit
, calpain-1 large subunit
, calpain 1