anti-Calpain 1 (CAPN1) Antibodies

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Additionally we are shipping CAPN1 Kits (12) and CAPN1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CAPN1 12333 O35350
CAPN1    
CAPN1    
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Top anti-CAPN1 Antibodies at antibodies-online.com

Showing 10 out of 109 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Western blot analysis of Calpain I expression in lysate from Jurkat cells treated with (Lane 1) or without (Lane 2) camptothecin. 100 μg Log in to see 2 to 3 Days
$245.00
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB IHC-P Image Calpain 1 antibody [N3C2], Internal detects Calpain 1 protein at cytoplasm on mouse lung by immunohistochemical analysis. Sample: Paraffin-embedded mouse lung. Calpain 1 antibody [N3C2], Internal , diluted at 1:500. ICC/IF Image Immunofluorescence analysis of methanol-fixed A431, using Calpain 1, antibody at 1:200 dilution. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450nm. Paraformaldehyde-fixed, paraffin embedded mouse liver tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-Calpain 1 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ICC, FACS, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Jurkat 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using Calpain 1, antibody at 1:500 dilution. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Calpain 1 Antibody [NBP1-88205] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17.Lane 2: Human cell line RT-4 Immunofluorescence: Calpain 1 Antibody [NBP1-88205] - Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Calpain 1 Antibody [NBP2-15670] - Confocal immunofluorescence analysis of methanol-fixed A431, using Calpain 1 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000. Western Blot: Calpain 1 Antibody [NBP2-15670] - Sample (30 ug of whole cell lysate) A: Jurkat 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: Calpain 1 Antibody [NBP2-15671] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution. Western Blot: Calpain 1 Antibody [NBP2-15671] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Anti-CAPN1 / Calpain 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details

Top referenced anti-CAPN1 Antibodies

  1. Human Polyclonal CAPN1 Primary Antibody for IF (cc), IF (p) - ABIN737646 : Miners, Renfrew, Swirski, Love: Accumulation of ¿-synuclein in dementia with Lewy bodies is associated with decline in the ¿-synuclein-degrading enzymes kallikrein-6 and calpain-1. in Acta neuropathologica communications 2014 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal CAPN1 Primary Antibody for WB - ABIN222978 : Jayanthi, Deng, Noailles, Ladenheim, Cadet: Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 (PubMed)

  3. Human Polyclonal CAPN1 Primary Antibody for IHC (p), WB - ABIN965738 : Imajoh, Aoki, Ohno, Emori, Kawasaki, Sugihara, Suzuki: Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease. in Biochemistry 1989 (PubMed)

More Antibodies against CAPN1 Interaction Partners

Mouse (Murine) Calpain 1 (CAPN1) interaction partners

  1. Calpain-1 deficiency impairs mGluR-dependent LTD and fear memory extinction.

  2. calpain contributes to the regulation of new gene expression that is necessary for these memory processes as a regulator of Ca(2+)-signal transduction pathway.

  3. the present study suggested that ephrinB/EphB signaling contributes to spinal nociceptive processing via the actions of calpain1 and caspase3.

  4. Authors provide the first evidence that calpain-1 regulates platelet hyperactivity in sickle mice.

  5. A total of 55 genes were differentially expressed in micro-calpain knockout mice.

  6. calpains inhibition plays crucial roles in vascular restenosis by preventing neointimal hyperplasia at the early stage via suppression of the MMP2/TGF-beta1 pathway.

  7. indicate that calpain-1 and calpain-2 play opposite roles in high increased intraocular pressure-induced ischemic injury

  8. Results strengthen the roles of both calpain-1 and PHLPP1 in synaptic plasticity and learning and memory, and illustrate the complexities of the interactions between multiple pathways participating in synaptic plasticity.

  9. Genetic ablation of calpain-1 ameliorates chronic pain behavior in sickle cell mice.

  10. Our results indicate that calpain mediates cytokine-induced collagen-I synthesis and proliferation of ASMCs via the mTORC2/Akt signalling pathway, thereby regulating airway smooth muscle remodelling in asthma.

  11. mutations in CAPN1 are an additional cause of ataxia in mammals, including humans.

  12. Results indicate that calpain-1 and calpain-2 are differentially activated in hippocampus following seizure activity, with calpain-1 activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 is widely activated in pyramidal neurons of CA1 and CA3, and triggers neurodegenerative cascades.

  13. Here we show the combined loss of glial glutamate transporters GLT1 and GLAST in spinal cord caused motor neuronal death and hindlimb paralysis.

  14. These results suggested that Streptococcus pneuomoniae PLY induces the influx of calcium in Streptococcus pneumoniae-infected macrophages, followed by calpain activation and subsequent IL-1alpha maturation and secretion.

  15. High calpain expression is associated with brain injury.

  16. the expression of the full-length 60-kDa calcineurin protein is down-regulated due to over-activated calpain that cleaves calcineurin to form a 45-kDa fragment.

  17. calpains and calpastatin in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22-5HTT(+) strain) PH, were investigated.

  18. Attenuation of atherosclerotic lesions/inflammation in ApoE KO mice by simvastatin might be associated with the downregulation of CD36 and calpain-1.

  19. Leukocyte calpain-1/calpain-2 deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.

  20. TnT3 regulates transcription of Cacna1s, the gene encoding Cav1.1. Knocking down TnT3 in vivo downregulated Cav1.1.

CAPN1 Antigen Profile

Protein Summary

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

Gene names and symbols associated with anti-Calpain 1 (CAPN1) Antibodies

  • calpain 1 (CAPN1) antibody
  • calpain 1 (Capn1) antibody
  • zgc:55262 (zgc:55262) antibody
  • Capa-1 antibody
  • Capa1 antibody
  • Capn1 antibody
  • fj67g01 antibody
  • mu-calpin antibody
  • wu:fj67g01 antibody

Protein level used designations for anti-Calpain 1 (CAPN1) Antibodies

calpain 1, large subunit , CANP 1 , calcium-activated neutral proteinase 1 , calpain mu-type , calpain-1 catalytic subunit , calpain-1 large subunit , micromolar-calpain , mu-calpain , muCANP , calpain 1

GENE ID SPECIES
443130 Ovis aries
12333 Mus musculus
406768 Danio rerio
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