Calpain 1 Proteins (CAPN1)

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.. Additionally we are shipping CAPN1 Antibodies (110) and CAPN1 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse CAPN1 CAPN1 12333 O35350
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Top CAPN1 Proteins at

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Human Human Un-conjugated   100 μg 2 to 3 Days
Pig Pig Un-conjugated 100 μg 2 to 3 Days
Human Human Un-conjugated   100 μg 3 to 4 Days
Human Un-conjugated   10 μg 6 Days

CAPN1 Proteins by Origin and Source

Origin Expressed in
Pig (Porcine)

Top referenced CAPN1 Proteins

  1. Human CAPN1 Protein expressed in Human - ABIN411905 : Huang, Zhou, Saberwal, Konieczna, Horvath, Katsoulidis, Platanias, Eklund: Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription. in Molecular and cellular biology 2010 (PubMed)
    Show all 7 Pubmed References

More Proteins for Calpain 1 (CAPN1) Interaction Partners

Mouse (Murine) Calpain 1 (CAPN1) interaction partners

  1. the involvement of calpain in survival motor neuron 1 regulation on motor neurons, was examined.

  2. Our data indicate that calpain-1 activity is neuroprotective and calpain-2 activity is neurodegenerative after traumatic Brain Injury

  3. In this chapter we describe a method to knockdown calpain 1 in mouse pulmonary vascular endothelium using delivery of siRNA/cationic liposome complex

  4. 1) that decrease of GLUT3 is associated with the reduction of protein O-GlcNAcylation in Alzheimer's disease (AD)brain, 2) that GLUT3 level is negatively correlated with calpain I activation in human brain, 3) that calpain I proteolyzes GLUT3 at the N-terminus in vitro, and 4) that activation of calpain I is negatively correlated with protein O-GlcNAcylation in AD brain.

  5. Calpain-1 null neutrophils failed to migrate through TNF-activated endothelial monolayers.

  6. Calpain-1 deficiency impairs mGluR-dependent LTD and fear memory extinction.

  7. calpain contributes to the regulation of new gene expression that is necessary for these memory processes as a regulator of Ca(2+)-signal transduction pathway.

  8. the present study suggested that ephrinB/EphB signaling contributes to spinal nociceptive processing via the actions of calpain1 and caspase3.

  9. Authors provide the first evidence that calpain-1 regulates platelet hyperactivity in sickle mice.

  10. A total of 55 genes were differentially expressed in micro-calpain knockout mice.

  11. calpains inhibition plays crucial roles in vascular restenosis by preventing neointimal hyperplasia at the early stage via suppression of the MMP2/TGF-beta1 pathway.

  12. indicate that calpain-1 and calpain-2 play opposite roles in high increased intraocular pressure-induced ischemic injury

  13. Results strengthen the roles of both calpain-1 and PHLPP1 in synaptic plasticity and learning and memory, and illustrate the complexities of the interactions between multiple pathways participating in synaptic plasticity.

  14. Genetic ablation of calpain-1 ameliorates chronic pain behavior in sickle cell mice.

  15. Our results indicate that calpain mediates cytokine-induced collagen-I synthesis and proliferation of ASMCs via the mTORC2/Akt signalling pathway, thereby regulating airway smooth muscle remodelling in asthma.

  16. mutations in CAPN1 are an additional cause of ataxia in mammals, including humans.

  17. Results indicate that calpain-1 and calpain-2 are differentially activated in hippocampus following seizure activity, with calpain-1 activation being limited to a small population of interneurons, and possibly triggering neuroprotective events, while calpain-2 is widely activated in pyramidal neurons of CA1 and CA3, and triggers neurodegenerative cascades.

  18. Here we show the combined loss of glial glutamate transporters GLT1 and GLAST in spinal cord caused motor neuronal death and hindlimb paralysis.

  19. These results suggested that Streptococcus pneuomoniae PLY induces the influx of calcium in Streptococcus pneumoniae-infected macrophages, followed by calpain activation and subsequent IL-1alpha maturation and secretion.

  20. High calpain expression is associated with brain injury.

CAPN1 Protein Profile

Protein Summary

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

Gene names and symbols associated with Calpain 1 Proteins (CAPN1)

  • calpain 1 (CAPN1)
  • calpain 1 (Capn1)
  • zgc:55262 (zgc:55262)
  • Capa-1 protein
  • Capa1 protein
  • Capn1 protein
  • fj67g01 protein
  • mu-calpin protein
  • wu:fj67g01 protein

Protein level used designations for Calpain 1 Proteins (CAPN1)

calpain 1, large subunit , CANP 1 , calcium-activated neutral proteinase 1 , calpain mu-type , calpain-1 catalytic subunit , calpain-1 large subunit , micromolar-calpain , mu-calpain , muCANP , calpain 1

443130 Ovis aries
12333 Mus musculus
406768 Danio rerio
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