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The protein encoded by CTAG1B is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. Additionally we are shipping Cancer/testis Antigen 1B Antibodies (122) and Cancer/testis Antigen 1B Proteins (2) and many more products for this protein.
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A significant association was found between AKAP4 (show AKAP4 ELISA Kits) gene expression and metastasis (P-value: 0.045), expression of the CTAG1B (NY-ESO-1) gene was not observed in our cases.
In 22 melanoma patients with stage III lymph node metastasis, overall survival was significantly higher in the XAGE-1b and NY-ESO-1 double-negative group than in the other groups.
The present results indicate the strong humoral immune response against NY-ESO-1 in natural human T-cell leukemia virus type 1 infection, irrespective of the clinical status.
some autoantibodies, such as anti-MAGEA4, anti-CTAG1 or anti-TP53 (show TP53 ELISA Kits) and their combinations could possibly contribute to the development of cancer early detection tests (not necessarily restricted to gastric cancer) when being combined with other markers.
High NY-ESO-1 expression is associated with Lung Cancer.
Results support the potential utility of NY-ESO-1, PRAME, and MAGEA4 as targets for immunotherapy and as ancillary prognostic parameters in synovial sarcomas.
Data suggest that only a small fraction of HLA-A*02:01- (HA)-binding ESO peptides are immunogenic, namely those that have high peptide-binding strength and peptide/HA complex stability. This study involved comparison of in silico-predicted and observed cytotoxic T-lymphocyte recognition of tumor antigen epitopes in melanoma patients and transgenic/knockout mice. (ESO = tumor antigen NY-ESO-1)
These data demonstrate that MAGE-A1-, MAGE-A3 (show MAGEA3 ELISA Kits)-, and NY-ESO-1-specific T cells with antigen-specific cytotoxicity can be cultured from healthy donors and patient-derived cells making adoptive immunotherapy with these cytotoxic T lymphocyte feasible.
Comparing the overall expression of CTAs, a decreased expression of all melanoma-associated (show ZNF654 ELISA Kits) antigens (MAGEs) post-treatment and a slightly increased expression of New York esophageal squamous cell carcinoma 1 (NY-ESO-1) was visible. The simultaneous cytoplasmic and nuclear expression of pan-MAGE or MAGE-A3 (show MAGEA3 ELISA Kits)/A4 correlated with reduced treatment-failure-free-survival (TFFS).
MAGE-A is more highly expressed than NY-ESO-1 in a majority of human malignancies
The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence.
New York esophageal squamous cell carcinoma 1
, autoimmunogenic cancer/testis antigen NY-ESO-1
, cancer antigen 3
, cancer/testis antigen 1
, cancer/testis antigen 6.1
, l antigen family member 2