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Carcinoembryonic antigen (CEA\\\\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma.
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Human Monoclonal CEACAM1/3/6 Primary Antibody for IHC (fro), FACS - ABIN2472302
NGuessan, Vigelahn, Bachmann, Zabel, Opitz, Schmeck, Hippenstiel, Zweigner, Riesbeck, Singer, Suttorp, Slevogt: The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells. in The Journal of infectious diseases 2007
Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1 (show CEACAM1 Antibodies), CEACAM3 (show CEACAM3 Antibodies), CEACAM5 (show CEACAM5 Antibodies) or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA (show S100A8 Antibodies) into host cells.
Here, the authors identify members of the carcinoembryonic antigen (show CEACAM5 Antibodies)-related cell adhesion molecule (show MCAM Antibodies) (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1 (show CEACAM1 Antibodies), CEACAM3 (show CEACAM3 Antibodies), CEACAM5 (show CEACAM5 Antibodies) and CEACAM6.
CD66c (KOR (show OPRK1 Antibodies)-SA3544) antigen expression of leukemic blasts in pediatric acute myeloid leukemia (show BCL11A Antibodies) with TLS/FUS (show FUS Antibodies)-ERG (show ERG Antibodies) fusion transcript
Data suggest that the expression of these TSPAN8 (show TSPAN8 Antibodies), LGALS4 (show LGALS4 Antibodies), COL1A2 (show COL1A2 Antibodies) and CEACAM6 in the whole blood may be useful in the detection of colorectal cancer (CRC (show CALR Antibodies)).
a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO (show MPO Antibodies), CEACAM8, CRISP3 (show CRISP3 Antibodies), MS4A3 (show MS4A3 Antibodies), CEACAM6, HEMGN (show HEMGN Antibodies), and MMP8 (show MMP8 Antibodies)
In enterocytic C2BBe1 cells, Candida albicans caused a transient tyrosine phosphorylation of CEACAM1 (show CEACAM1 Antibodies) and induced higher expression of membrane-bound CEACAM1 (show CEACAM1 Antibodies) and soluble CEACAM6.
show the upregulation of the tumor-associated antigens CEACAM5 (show CEACAM5 Antibodies)/6 by trans-signaling of the pro-inflammatory cytokine IL-6 (show IL6 Antibodies)
Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another.
vaccination with recombinant attenuated Salmonella harboring the CEACAM6 and 4-1BBL (show TNFSF9 Antibodies) gene efficiently increased the number of CD3 (show CD3 Antibodies)+CD8 (show CD8A Antibodies)+ TIL (show TLR1 Antibodies) and NK cells, decreased the number of FOXP3 (show FOXP3 Antibodies) cells and inhibited the development of DMH (show DST Antibodies)-induced colorectal cancer
CEACAM6 increased the levels of phosphorylated AKT (show AKT1 Antibodies), which is involved in the progression of a variety of human tumors.
Carcinoembryonic antigen (CEA\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988
carcinoembryonic antigen-related cell adhesion molecule 6
, non-specific crossreacting antigen
, normal cross-reacting antigen