Cellular Retinoic Acid Binding Protein 2 (CRABP2) ELISA Kits

Zebrafish Cellular Retinoic Acid Binding Protein 2 (CRABP2) interaction partners

1. Zebrafish Crabp2a and Crabp2b are essential for expression of hoxb4 and hoxb5 in the hindbrain.

2. crabp2a mRNA was detected in total RNA extracted from whole adult zebrafish, adult zebrafish muscle, testes, and skin and to a lesser extent in heart, ovary and brain.

Pig (Porcine) Cellular Retinoic Acid Binding Protein 2 (CRABP2) interaction partners

1. Chromosome mapping of CRABP1 AND CRABP2 in swine.

Human Cellular Retinoic Acid Binding Protein 2 (CRABP2) interaction partners

1. Semiquantitative and quantitative analyses of the markers RARA and CRABP2 indicate their potential as biomarkers for tumor progression and their participation in nephroblastoma tumorigenesis

2. These data suggest a retinoic acid-independent, non-tumor suppressor role of CRABP2 for the survival of Malignant peripheral nerve sheath tumor (MPNST) cells in vitro. Targeting CRABP2 overexpression may represent a unique approach for the treatment of human MPNST.

3. A high expression ratio between FABP5 and CRABPII may be related to CP tumor recurrence and ATRA could be a potential therapeutic agent for CP chemotherapy.

4. Holo-CRABPs had higher affinity for CYP26B1 than free atRA, but both apo-CRABPs(CRABP-I and CRABP-II ) inhibited the formation of 4-OH-RA by CYP26B1.

5. reducing CRABP2 levels may enhance the therapeutic index of Retinoic acid in glioblastoma multiforme patients

6. in esophageal squamous carcinogenesis by significantly inhibiting cell growth, inducing cell apoptosis and blocking cell metastasis both in vitro and in vivo

7. The anticarcinogenic activities of CRABP2 are mediated by both HuR and RAR.

8. CBX3 and CRABP2 expression was markedly increased in lung cancer tissues

9. we demonstrated significant changes in CRABP1 and CRABP2 expression in non-small cell lung cancer samples

10. Reengineering of cellular retinoic acid binding protein II (CRABPII) to be capable of binding retinal as a protonated Schiff base is described

11. CRABP2 controls mRNA stabilization by HuR.

12. Factors involved in the retinoid pathway, in particular upregulation of CRBP, CRABP1 and CRABP2, also showed differential expression in tumors with different histological subtypes

13. overexpression of CRABP-II is a late event of pancreatic carcinogenesis, and it could be used as a diagnostic marker

14. all three proteins (RDH10, RALDH2, and CRABP2) appeared to be required for ATRA production induced by activation of PPARgamma

15. E-FABP showed high exp ression in NSCLC, and the increased E-FABP expression may involved in the occurrence and development of NSCLC

16. Hypermethylation in the CpG island of the CRABP2 gene is associated with astrocytic gliomas.

17. Aberrant methylation in CRABP-II reduces the expression of CRABP-II that in turn confers retinoic acid resistance in medulloblastoma cells.

18. Low CRABP2 is associated with pancreatic ductal adenocarcinoma.

19. Nuclear translocation of cellular retinoic acid-binding protein II is regulated by retinoic acid-controlled SUMOylation

20. Trophoblast spheroids cocultured with endometrial cells overexpressing CRABP2 are defective in expansion and exhibit apoptosis, suggesting that CRABP2 is involved in abnormal endometrium-trophoblast interaction, leading to implantation failure.

Mouse (Murine) Cellular Retinoic Acid Binding Protein 2 (CRABP2) interaction partners

1. The anticarcinogenic activities of CRABP2 are mediated by both HuR and RAR.

2. Results show that acetylation status of CRABPII directly influences embryonic stem cell differentiation in response to retinoic acid.

3. CRABP2 controls mRNA stabilization by HuR.

4. all three proteins (RDH10, RALDH2, and CRABP2) appeared to be required for ATRA production induced by activation of PPARgamma

5. CRABP2 promotes myoblast differentiation and is modulated by the transcription factors MyoD and Sp1 in C2C12 cells.

6. observations emphasize the important role of CRABP-II in regulating the transcriptional activity of RA through RAR, and they demonstrate that repression of this gene is critical for allowing adipogenesis to proceed

7. Localization revealed epithelial-mesenchymal interactions, differentiation differences within the retinoic acid biosynthesis and signaling pathway, and observations on nuclear versus cytoplasmic locations of Crabp2 and RA receptors (alpha, beta, gamma).

8. Increases in CRABPI and II transcripts in the absence of leukemia inhibitory factor may regulate aspects of embryonic stem cell differentiation in response to retinol.

9. TIS7 inhibits CRABP II expression during axonal regeneration, thereby modulating retinoic acid signalling. Hence, neurite initiation and branching are regulated by a negative feedback mechanism involving TIS7 and CRABP II.