anti-Chemokine (C-C Motif) Ligand 4 (CCL4) Antibodies

The protein encoded by CCL4 is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. Additionally we are shipping CCL4 Kits (131) and CCL4 Proteins (74) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCL4 6351 P13236
CCL4 116637 P50230
CCL4 20303 P14097
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Top anti-CCL4 Antibodies at

Showing 10 out of 250 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated CyTOF, ELISA (Capture), FACS, Neut, WB Chemotaxis Induced by CCL4/MIP-1 beta and Neutralization by Human CCL4/MIP-1 beta Antibody. Recombinant Human CCL4/MIP-1 beta. The ND50 is typically 0.3-1.2 ug/mL. Detection of CCL4/MIP-1 beta in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monoctyes treated with LPS and Monensin for 5 hours were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
Human Mouse Fluorescein FACS Detection of CCL4/MIP-1 beta in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes treated with LPS and Monensin for 5 hours were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Rat Rabbit Un-conjugated WB Anti-CCL4 Picoband antibody,  All lanes: Anti-CCL4 at 0.5ug/ml WB: Recombinant Rat CCL4 Protein 0.5ng Predicted bind size: 36KD Observed bind size: 36KD 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated ELISA, WB Observed bind size: 11KD 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated WB Western blot analysis of CCL4 expression in HL60 (A), 22RV1 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Pig Rabbit Un-conjugated ELISA, WB Western blot using  protein-A purified Anti-MIP-1ß (CCL4) antibody shows detection of recombinant swine MIP-1ß (CCL4) raised in yeast. The protein was purified and resolved by SDS-PAGE, then transferred to PVDF membrane. Membrane was blocked with 3% BSA (BSA-30, diluted 1:10), and probed with 4 µg/mL primary antibody overnight at 4°C. After washing, membrane was probed with Conjugated Goat Anti-Rabbit IgG  at 1:20,000 for 45 min at room temperature. 100 μg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.4 mL Log in to see 4 to 8 Days
Human Rabbit Un-conjugated IHC, Neut, RIA, ELISA, WB anti-Human MIP-1ß antibody shows detection of a band ~15 kDa in size corresponding to recombinant human MIP-1ß. The identity of the faint higher molecular weight band may represent a homodimer. Molecular weight markers are also shown (left). After transfer, the membrane was blocked overnight with 3% BSA in TBS followed by reaction with primary antibody at a 1:1,000 dilution. Detection occurred using peroxidase conjugated anti-Rabbit IgG  secondary antibody diluted 1:40,000 in blocking buffer  for 30 min at RT followed by reaction with chemiluminescent substrate. Image was captured using MP 4000 imaging system (Bio-Rad). 100 μg Log in to see 5 to 7 Days

Top referenced anti-CCL4 Antibodies

  1. Human Monoclonal CCL4 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899855 : Hu, Kwun, Aizenstein, Knechtle: Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. in Transplantation 2009 (PubMed)
    Show all 14 Pubmed References

  2. Human Monoclonal CCL4 Primary Antibody for FACS - ABIN4896817 : Meythaler, Wang, Martinot, Pryputniewicz, Kasheta, McClure, ONeil, Kaur: Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 12 Pubmed References

  3. Mouse (Murine) Polyclonal CCL4 Primary Antibody for WB - ABIN966576 : Kamin-Lewis, Abdelwahab, Trang, Baker, DeVico, Gallo, Lewis: Perforin-low memory CD8+ cells are the predominant T cells in normal humans that synthesize the beta -chemokine macrophage inflammatory protein-1beta. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CCL4 Primary Antibody for FACS - ABIN4896818 : Shin, You, Kang, Lee, Yoo, Park, Kang, Kim, Mohanty, Shaw, Montgomery, Hwang, Kang: DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal CCL4 Primary Antibody for ELISA, WB - ABIN1043803 : Guan, Wang, Roderiquez, Norcross: Natural truncation of the chemokine MIP-1 beta /CCL4 affects receptor specificity but not anti-HIV-1 activity. in The Journal of biological chemistry 2002 (PubMed)

  6. Human Polyclonal CCL4 Primary Antibody for Func, IHC (p) - ABIN2475707 : Cocchi, DeVico, Garzino-Demo, Arya, Gallo, Lusso: Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal CCL4 Primary Antibody for EIA, WB - ABIN116166 : Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  8. Mouse (Murine) Polyclonal CCL4 Primary Antibody for IP, Neut - ABIN223562 : Neff, Zgraggen, Neff, Jamnicki-Abegg, Suter, Schimmer, Booy, Joch, Pasch, Ward, Beck-Schimmer: Inflammatory response of tracheobronchial epithelial cells to endotoxin. in American journal of physiology. Lung cellular and molecular physiology 2005 (PubMed)

More Antibodies against CCL4 Interaction Partners

Human Chemokine (C-C Motif) Ligand 4 (CCL4) interaction partners

  1. These data suggest that TNF-alpha drives CCL4 expression in THP-1 monocytic cells/macrophages via the activation of SAPK/JNK and NF-kappaB pathways.

  2. Results indicate the potential association of decreased macrophage inflammatory protein (MIP)-1alpha (MIP-1alpha) and MIP-1beta levels with the prospective risk of nasopharyngeal carcinoma (NPC) development in southern China.

  3. Our study revealed that CCL2 and CCL4 expression levels could serve as potential prognostic biomarkers and therapeutic targets for non small cell lung cancer patients

  4. nucleotide T over the rs1719153 is associated with decreased CCL4 gene expression and decreased risk for rheumatoid arthritis

  5. Variations in the CCL4 gene may help to predict breast cancer progression and metastasis.

  6. SNPs in CCL11 and CCL4 were associated with elevated plasma chemokine levels in fibromyalgia patients.

  7. High chemokine CCL4 expression is associated with colorectal cancer.

  8. Given that IL-8, MIP-1beta, and MCP-1 are chemokines that play important roles in recruitment of immunocompetent cells for immune defense and tumor cell clearance, the observed lower levels of these markers with increasing PM2.5 exposure may provide insight into the mechanism by which DEE promotes lung cancer.

  9. Results highlight the role of phytohaemagglutin-stimulated peripheral blood mononuclear cells from patients with Alzheimer's disease on the expression of chemokines CXCL10 and CCL4 by endothelial cells and H4 cell line (mimicking the brain parenchyma) in a human blood brain barrier model.

  10. results suggested that genetic variants at the CCL3 and CCL4 loci may be marker SNPs for risk of HCV treatment outcome.

  11. The data of the present study suggest that M1 macrophage-derived foam cells induce endothelial-mesenchymal transition by upregulating CCL-4, and increase endothelial permeability and monocyte adhesion.

  12. We found that the A/G homozygotes of CCL4 rs10491121 polymorphism reduced the risks for Hepatocellular carcinoma (HCC). The present report is the first time to examine the risk factors associated with CCL4 SNPs in HCC progression in Taiwan.

  13. Our results suggest that the CCL4 rs1634507 SNP have potential predictive significance in oral carcinogenesis. Gene-environment interactions of CCL4 polymorphisms might influence oral-cancer susceptibility. CCL4 rs10491121 may be a factor to predict the tumor size in OSCC patients.

  14. The CCL3 and CCL4 chemokines might not be involved in differential susceptibility to the digestive and cardiac clinical forms of chronic Chagas disease, and it seems they do not influence the development of LVSD.

  15. The serum levels of IL-8, MIP-1 alpha, MIP-1 beta, MMP-8, Resistin, FLRG, and BCAM were significantly higher in breast cancer patients, but LAP and TSH-beta levels were lower.

  16. MIP-1beta is a candidate biomarker for PTSD only in females.

  17. study is the first one to report Ang1 capacity to induce MIP-1beta gene expression, protein synthesis and release from neutrophils, and that these effects are mediated by PI3K, p38 MAPK and MEK activation and downstream NF-kappaB activation

  18. Macrophages promote glioblastoma cell invasion by the CCL4-CCR5 axis, and hypoxia enhances the interaction between these two types of cells by upregulating both CCL4 and CCR5 expression, respectively.

  19. The reduction of circulating levels of MCP-4, eotaxin-3, and MIP-1beta could be one of the mechanisms by which bariatric surgery contributes to the reduction of cardiovascular risk in these patients.

  20. MCP-1, MIP-1beta, and IP-10 may modify the pathologic features of Rhegmatogenous Retinal Detachment.

Pig (Porcine) Chemokine (C-C Motif) Ligand 4 (CCL4) interaction partners

  1. In swine, IL-8, TNF-ALPHA, INOS AND MIP-1BETA were increased during mechanical ventilation in a time-related fashion.

Mouse (Murine) Chemokine (C-C Motif) Ligand 4 (CCL4) interaction partners

  1. High dilutions of antimony modulate cytokines production and macrophage - Leishmania (L.) amazonensis interaction in vitro.(

  2. CCL4-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity.

  3. YY1 regulates lung CCL4 transcription in pulmonary tuberculosis.

  4. Ccl4 mRNAs increased within 5 h after injury in mouse cortical slices.

  5. The chemokines monocyte chemotactic protein 1 (MCP1), MIP1alpha, MIP1beta, interferon gamma-induced protein 10 (IP-10), and eotaxin were induced in Saa1 TG mice.

  6. Aged mice had similar levels of IL-1beta, TNF, IFN-gamma, IL-17, and granulocyte colony-stimulating factor following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9, CXCL12, CCL3, CCL4, CCL5, CCL11, and CCL17.

  7. CCL4 and CCL5 expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 T cells from WSX-1(-/-) mice expressed higher levels of CCR5 than cells from WT mice

  8. CCL4 upregulation was associated with increased Snail expression and downregulation of p53/PTEN in high-grade PIN and prostate cancer

  9. Data indicate that Bifidobacterium infantis feeding to Salmonella-infected mice significantly reduced Peyer's patch MIP-1alpha and MIP-1beta secretion.

  10. IFN-gamma and NOS2 repress CCL3 and CCL4 in vivo upon S. typhimurium infection of mice also repress CCL3 and CCL4 during S. typhimurium infection in bone marrow-derived macrophages.

  11. These results suggest that MIP-1beta is a novel key mediator, and the peripheral MIP-1beta-CCR5 axis contributes to neuropathic pain.

  12. results indicate that MIP-1beta is involved in the recruitment of bone marrow-derived monocyte lineage cells

  13. Data verified that the expression of CCR5 and its ligands, CCL3, CCL4 and CCL5, were increased in the thymus with age.

  14. MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines.

  15. increased responsiveness of murine eosinophils to MIP-1beta is mediated by CCR5 receptor in mice

  16. Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma

  17. MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity.

  18. After stimulation via high-affinity FcepsilonRI, the transcriptional levels of I-309 (CCL1), MIP-1alpha (CCL3) and MIP-1beta (CCL4) were found among the 10 most increased human and mouse transcripts from approximately 12 000 genes

  19. MIP-1alpha and MIP-1beta show diverging signaling capacities [review]

  20. PGE2 acts as an anti inflammatory agent and inhibits inflammatory chemokine release from activated dendritic cells.

CCL4 Antigen Profile

Protein Summary

The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions.

Gene names and symbols associated with CCL4

  • C-C motif chemokine ligand 4 (CCL4) antibody
  • chemokine (C-C motif) ligand 4 (CCL4) antibody
  • C-C motif chemokine ligand 4 (Ccl4) antibody
  • chemokine (C-C motif) ligand 4 (Ccl4) antibody
  • Act-2 antibody
  • ACT2 antibody
  • AT744.1 antibody
  • CCL4 antibody
  • G-26 antibody
  • HC21 antibody
  • K203 antibody
  • LAG-1 antibody
  • LAG1 antibody
  • MIP-1-beta antibody
  • MIP-1B antibody
  • MIP-1BETA antibody
  • Mip1-b antibody
  • Mip1b antibody
  • MIP1B1 antibody
  • SCY4A antibody
  • SCYA2 antibody
  • Scya4 antibody

Protein level used designations for CCL4

C-C motif chemokine 4 , G-26 T-lymphocyte-secreted protein , MIP-1-beta(1-69) , PAT 744 , SIS-gamma , T-cell activation protein 2 , lymphocyte activation gene 1 protein , macrophage inflammatory protein 1-beta , secreted protein G-26 , small inducible cytokine A4 (homologous to mouse Mip-1b) , CC chemokine ligand 4 , small-inducible cytokine A4 , chemokine C-C motif ligand 4 , chemokine K203 , putative MIP1-beta protein , chemokine (C-C motif) ligand 4 , MIP-1-beta , macrophage inflammatory protein-1 beta , small inducible cytokine A4 , C-C motif chemokine 4 homolog , chemokine-like ligand 1 , macrophage inflammatory protein 1-beta homolog , small-inducible cytokine A4 homolog , ACT-2 , immune activation gene 2 , immune activation protein 2 , ACT2 , MIP-1 beta

6351 Homo sapiens
448786 Canis lupus familiaris
395468 Gallus gallus
414347 Bos taurus
454593 Pan troglodytes
116637 Rattus norvegicus
395551 Gallus gallus
396668 Sus scrofa
100008984 Oryctolagus cuniculus
20303 Mus musculus
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