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Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Additionally we are shipping CXCL16 Kits (87) and CXCL16 Proteins (46) and many more products for this protein.
Showing 10 out of 194 products:
Human Polyclonal CXCL16 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900386
Dieudonné, Torres, Blanchard, Taront, Jeannin, Delneste, Pichavant, Trottein, Gosset: Scavenger receptors in human airway epithelial cells: role in response to double-stranded RNA. in PLoS ONE 2012
Show all 7 Pubmed References
Mouse (Murine) Polyclonal CXCL16 Primary Antibody for CyTOF, FACS - ABIN4899997
Eberlein, Nguyen, Victorino, Golden-Mason, Rosen, Homann: Comprehensive assessment of chemokine expression profiles by flow cytometry. in The Journal of clinical investigation 2010
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Mouse (Murine) Polyclonal CXCL16 Primary Antibody for ELISA (Detection), FACS - ABIN4899996
Gough, Garton, Wille, Rychlewski, Dempsey, Raines: A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. in Journal of immunology (Baltimore, Md. : 1950) 2004
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Human Polyclonal CXCL16 Primary Antibody for EIA, IHC (p) - ABIN116405
Gutwein, Abdel-Bakky, Schramme, Doberstein, Kämpfer-Kolb, Amann, Hauser, Obermüller, Bartel, Abdel-Aziz, El Sayed, Pfeilschifter: CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein. in The American journal of pathology 2009
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Human Polyclonal CXCL16 Primary Antibody for EIA, IHC (p) - ABIN116406
Scholz, Schulte, Adamski, Hundhausen, Mittag, Schwarz, Kruse, Proksch, Ludwig: Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin. in The Journal of investigative dermatology 2007
Show all 2 Pubmed References
Mouse (Murine) Polyclonal CXCL16 Primary Antibody for IF (p), IHC (p) - ABIN686572
Cottle, Ursino, Ip, Jones, Ditommaso, Hacking, Mangan, Mellett, Henley, Sviridov, Nold-Petry, Nold, Meikle, Kile, Smyth: Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. in Human molecular genetics 2014
Women with gestational diabetes mellitus and preeclampsia had a dysregulated CXC chemokine ligand 16 during pregnancy, and in gestational diabetes mellitus, the increase in CXC chemokine ligand 16 early in pregnancy and after 5 years was strongly associated with their lipid profile.
Data suggest that primary cells from papillary renal cell carcinoma (show MOK Antibodies) secrete the chemokines IL8 (show IL8 Antibodies), CXCL16, and chemerin (show RARRES2 Antibodies); these chemokines attract primary human monocytes and induce shift/transdifferentiation in monocytes toward M2 macrophage/foam cell phenotype. (IL8 (show IL8 Antibodies) = interleukin-8 (show IL8 Antibodies); CXCL16 = C-X-C motif chemokine (show CCL1 Antibodies) ligand 16)
Our study demonstrated that CXCL16-CXCR6 (show CXCR6 Antibodies) mediates CD8 (show CD8A Antibodies)(+) T-cell skin trafficking under oxidative stress in patients with vitiligo (show MITF Antibodies), and CXCL16 expression in human keratinocytes induced by ROS (show ROS1 Antibodies) is, at least in part, caused by unfolded protein response activation
eGFR (show EGFR Antibodies) and serum albumin (show ALB Antibodies) had an independent and significant negative correlation with plasma CXCL16 in diabetic kidney disease.
The expression of CXCL16 and and its receptor, CXCR6 (show CXCR6 Antibodies), their immunolocalization in disc tissue and their presence following exposure of cultured human annulus fibrosus cells to proinflammatory cytokines are reported.
Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via activation of the CXCL16/CXCR6 (show CXCR6 Antibodies) pathway, which may be regulated by P2X7R (show P2RX7 Antibodies).
CXCL16 single nucleotide polymorphisms significantly impacted myocardial infarction risk in a Chinese Han population.
Transmembrane-CXCL16 specifically acts as a receptor for soluble-CXCL16 in human meningioma cells.
Higher levels CXCL16 may be a biomarker for predicting stroke incidence and might contribute to plaque destabilization.
CXCL16 is released into the circulation as a result of cardiac surgery and that high post-operative CXCL16 levels are associated with an increased severity of post-operative organ dysfunctions.
CXCL16 plays a crucial role in the pathogenesis of cisplatin-induced acute kidney injury through regulation of apoptosis and inflammation.
These findings suggest that the CXCL16 gene product promotes inflammatory factors and cell infiltration factors, and inhibits the expression of antioxidant factors to accelerate the development of DN, and CXCL16 deficiency attenuates DN may be involved in the AKT (show AKT1 Antibodies) signaling pathway.
Results indicate that CXCL16 plays a pivotal role in the pathogenesis of renal artery stenosis-induced renal injury and fibrosis through regulation of bone marrow-derived fibroblast accumulation and macrophage and T-cell infiltration.
Simvastatin exerts a protective effect on renal function and structure in mice with ADR (show SARS Antibodies) nephropathy which related to the decreasing expression of CXCL16 in glomerular podocytes followed by the decreasing endocytosis of ox-LDL in podocytes and inhibition of NF-kappaB (show NFKB1 Antibodies) pathway activation.
These results indicate that MEK (show MDK Antibodies) inhibitor diminishes Nasopharyngeal carcinoma cell proliferation and NPC (show NPC1 Antibodies)-induced osteoclastogenesis via modulating CCL2 (show CCL2 Antibodies) and CXCL16 expressions.
Serum CXCL16 is increased in severe pancreatitis with infected pancreatic necrosis and identifies patients who benefit from surgical necrosectomy
injured hepatocytes up-regulated CXCL16 expression, indicating that scavenging functions of CXCL16 might be additionally involved in the pathogenesis of NAFLD (show TSC2 Antibodies).
role of IFN-gamma (show IFNG Antibodies), CXCL16, and ADAM10 (show ADAM10 Antibodies) in oxLDL-induced lipid accumulation in glomerular podocytes
CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-alpha (show TNF Antibodies)-induced apoptosis by tumor-associated macrophages.
Loss of sst2 (show SSTR2 Antibodies) from pancreatic tissues activates PI3K signaling via AKT (show AKT1 Antibodies), leading to activation of NF-kappaB (show NFKB1 Antibodies), amplification of oncogenic KRAS signaling, increased expression of CXCL16, and pancreatic tumor formation.
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
chemokine (C-X-C motif) ligand 16
, small inducible cytokine B14
, C-X-C motif chemokine 16
, CXC chemokine ligand 16
, scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
, small-inducible cytokine B16
, transmembrane chemokine CXCL16
, Cxc chemokine ligand 16
, zinc finger, MYND-type containing 15
, Transmembrane chemokine CXCL16