anti-Chemokine (C-X-C Motif) Ligand 16 (CXCL16) Antibodies

Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Additionally we are shipping CXCL16 Kits (93) and CXCL16 Proteins (49) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCL16 66102 Q8BSU2
CXCL16 58191 Q9H2A7
CXCL16 497942 Q6AXU5
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Top anti-CXCL16 Antibodies at antibodies-online.com

Showing 10 out of 181 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CXCL16 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated CyTOF, ELISA (Capture), FACS, IHC, Neut, WB Chemotaxis Induced by CXCL16 and Neutralization by Human CXCL16 Antibody. Recombinant Human CXCL16 Chemokine Domain. The ND50 is typically 0.05-0.25 ug/mL. CXCL16 in Human Lymphoma. CXCL16 was detected in immersion fixed paraffin-embedded sections of human lymphoma using Goat Anti-Human/Primate CXCL16 Antigen Affinity-purified Polyclonal Antibody. Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. 100 μg Log in to see 8 to 9 Days
$463.45
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of CXCL16 expression in CEM whole cell lysates ( Lane 1) and A549 whole cell lysates ( Lane 2). CXCL16 at 35KD was detected using rabbit anti- CXCL16 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Log in to see 4 to 6 Days
$240.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti-CXCL16 antibody, IHC(P) IHC(P): Mouse Spleen Tissue Anti-CXCL16 antibody, Western blotting Lane 1: Recombinant Mouse CXCL16 Protein 10ng Lane 2: Recombinant Mouse CXCL16 Protein 5ng Lane 3: Recombinant Mouse CXCL16 Protein 2.5ng 100 μg Log in to see 4 to 6 Days
$280.00
Details
Mouse Goat Un-conjugated CyTOF, FACS, Neut, WB Chemotaxis Induced by CXCL16 and Neutralization by Mouse CXCL16 Antibody. Recombinant Mouse CXCL16 Chemokine Domain. The ND50 is typically 0.1-0.4 ug/mL. 100 μg Log in to see 8 to 9 Days
$440.45
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Thymus lysate; Primary Ab: 5µg/ml Rabbit Anti-Mouse CXCL16 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 15 to 18 Days
$324.00
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$639.83
Details
Human Rat APC FACS Detection of CXCL16 in Human Denditic Cells by Flow Cytometry. Human monocyte-derived dendritic cells were stained with Rat Anti-Human CXCL16 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$399.05
Details
Human Rat Un-conjugated CyTOF, FACS, Neut, WB Chemotaxis Induced by CXCL16 and Neutralization by Human CXCL16 Antibody. Recombinant Human CXCL16 Chemokine Domain. The ND50 is typically 2-8 ug/mL. 100 μg Log in to see 8 to 9 Days
$293.25
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CXCL16 Polyclonal Antibody, Unconjugated (ABIN686572) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse brain tissue  labeled with Anti-CXCL16 Polyclonal Antibody, unconjugated  (ABIN686572) followed by incubation with conjugated secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$318.45
Details

Top referenced anti-CXCL16 Antibodies

  1. Human Polyclonal CXCL16 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900386 : Dieudonné, Torres, Blanchard, Taront, Jeannin, Delneste, Pichavant, Trottein, Gosset: Scavenger receptors in human airway epithelial cells: role in response to double-stranded RNA. in PLoS ONE 2012 (PubMed)
    Show all 10 Pubmed References

  2. Mouse (Murine) Polyclonal CXCL16 Primary Antibody for CyTOF, FACS - ABIN4899997 : Eberlein, Nguyen, Victorino, Golden-Mason, Rosen, Homann: Comprehensive assessment of chemokine expression profiles by flow cytometry. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 Pubmed References

  3. Mouse (Murine) Polyclonal CXCL16 Primary Antibody for ELISA (Detection), FACS - ABIN4899996 : Gough, Garton, Wille, Rychlewski, Dempsey, Raines: A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Polyclonal CXCL16 Primary Antibody for IF (p), IHC (p) - ABIN686572 : Cottle, Ursino, Ip, Jones, Ditommaso, Hacking, Mangan, Mellett, Henley, Sviridov, Nold-Petry, Nold, Meikle, Kile, Smyth: Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. in Human molecular genetics 2014 (PubMed)

  5. Human Monoclonal CXCL16 Primary Antibody for FACS - ABIN4897616 : Reyat, Chimen, Noy, Szyroka, Rainger, Tomlinson: ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration. in Journal of immunology (Baltimore, Md. : 1950) 2017 (PubMed)

  6. Human Polyclonal CXCL16 Primary Antibody for EIA, IHC (p) - ABIN116406 : Gutwein, Abdel-Bakky, Schramme, Doberstein, Kämpfer-Kolb, Amann, Hauser, Obermüller, Bartel, Abdel-Aziz, El Sayed, Pfeilschifter: CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein. in The American journal of pathology 2009 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal CXCL16 Primary Antibody for EIA, IHC (p) - ABIN116405 : Scholz, Schulte, Adamski, Hundhausen, Mittag, Schwarz, Kruse, Proksch, Ludwig: Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin. in The Journal of investigative dermatology 2007 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CXCL16 Interaction Partners

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 16 (CXCL16) interaction partners

  1. the results of the present study suggested that CXCL16 may regulate the TRL4/NFkappaB/CXCL16 signaling pathway, and that miR146a and miR146b may negatively regulate CXCL16 via this pathway in atherosclerosis in vivo.

  2. Inflammation accelerates renal tubulointerstitial lesions in mouse model of diabetic nephropathy by increasing the activity of CXCL16 pathway.

  3. CXCL16 increases the frequency of the miniature excitatory synaptic currents (mEPSCs) and reduces the PPR (show PTH1R Antibodies) of evoked excitatory transmission, indicating that the chemokine (show CCL1 Antibodies) also modulates and enhances the release of glutamate (show GRIN1 Antibodies).

  4. results indicate that CXCL16 plays a key role in the pathogenesis of renal injury and fibrosis in salt-sensitive hypertension through regulation of bone marrow-derived fibroblast accumulation and macrophage and T cell infiltration.

  5. Data indicate that chemokine (show CCL1 Antibodies) C-X-C ligand 16 (CXCL16) is a critical regulator of liver immune response to acetaminophen (APAP)-induced hepatotoxicity, suggesting a potential strategy for the treatment of drug-induced acute liver failure by targeting CXCL16.

  6. CXCL16 plays a crucial role in the pathogenesis of cisplatin-induced acute kidney injury through regulation of apoptosis and inflammation.

  7. These findings suggest that the CXCL16 gene product promotes inflammatory factors and cell infiltration factors, and inhibits the expression of antioxidant factors to accelerate the development of DN, and CXCL16 deficiency attenuates DN may be involved in the AKT (show AKT1 Antibodies) signaling pathway.

  8. Results indicate that CXCL16 plays a pivotal role in the pathogenesis of renal artery stenosis-induced renal injury and fibrosis through regulation of bone marrow-derived fibroblast accumulation and macrophage and T-cell infiltration.

  9. Simvastatin exerts a protective effect on renal function and structure in mice with ADR (show SARS Antibodies) nephropathy which related to the decreasing expression of CXCL16 in glomerular podocytes followed by the decreasing endocytosis of ox-LDL in podocytes and inhibition of NF-kappaB (show NFKB1 Antibodies) pathway activation.

  10. These results indicate that MEK (show MDK Antibodies) inhibitor diminishes Nasopharyngeal carcinoma cell proliferation and NPC (show NPC1 Antibodies)-induced osteoclastogenesis via modulating CCL2 (show CCL2 Antibodies) and CXCL16 expressions.

Human Chemokine (C-X-C Motif) Ligand 16 (CXCL16) interaction partners

  1. demonstrate that macrophages can promote the migration and invasion of ovarian carcinoma cells by affecting the CXCL16/CXCR6 (show CXCR6 Antibodies) pathway

  2. activation of cancer-associated fibroblasts and expression of CXCL16, shown to be a monocyte chemoattractant.

  3. Enhanced CXCL16 expression in lung cancer tissue promoted the proliferation and invasion of lung cancer cells. CXCL16 might promote proliferation and invasion of lung cancer by regulating the NF-kappaB (show NFKB1 Antibodies) pathway.

  4. increased plasma sCXCL16 might be implicated in the pathogenesis of immune thrombocytopenia and have a relationship with Th1 (show TH1L Antibodies)/Th2 imbalance.

  5. Serum CXCL16 levels are significantly increased in patients with gallstone, and are independently associated with liver injury in Chinese population, suggesting that CXCL16 may be a biomarker of liver injury in subjects with gallstone or NAFLD (show TSC2 Antibodies). Hepatic CXCL16 mRNA and protein levels were also significantly increased in gallstone patients

  6. IFN-gamma (show IFNG Antibodies), CXCL16 and uPAR (show PLAUR Antibodies) are promising as effective biomarkers of disease activity, renal damage, and the activity of pathological lesions in systemic lupus erythematosus.

  7. Data showed that reverse signaling via CXCL16 promotes migration in CXCL16-expressing melanoma and glioblastoma cells, but does not affect proliferation or protection from chemically-induced apoptosis.

  8. Study showed, for the first time, highly significant relationships of circulating CXCL16 level with cardiac injury markers in dialysis patients.

  9. Women with gestational diabetes mellitus and preeclampsia had a dysregulated CXC chemokine ligand 16 during pregnancy, and in gestational diabetes mellitus, the increase in CXC chemokine ligand 16 early in pregnancy and after 5 years was strongly associated with their lipid profile.

  10. Data suggest that primary cells from papillary renal cell carcinoma (show MOK Antibodies) secrete the chemokines IL8 (show IL8 Antibodies), CXCL16, and chemerin (show RARRES2 Antibodies); these chemokines attract primary human monocytes and induce shift/transdifferentiation in monocytes toward M2 macrophage/foam cell phenotype. (IL8 (show IL8 Antibodies) = interleukin-8 (show IL8 Antibodies); CXCL16 = C-X-C motif chemokine (show CCL1 Antibodies) ligand 16)

CXCL16 Antigen Profile

Protein Summary

Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

Gene names and symbols associated with CXCL16

  • C-X-C motif chemokine ligand 16 (CXCL16) antibody
  • chemokine (C-X-C motif) ligand 16 (Cxcl16) antibody
  • C-X-C motif chemokine ligand 16 (Cxcl16) antibody
  • 0910001K24Rik antibody
  • AV290116 antibody
  • b2b498Clo antibody
  • BB024863 antibody
  • CXCL16 antibody
  • CXCL16v1 antibody
  • CXCL16v2 antibody
  • CXCLG16 antibody
  • SR-PSOX antibody
  • SRPSOX antibody
  • Zmynd15 antibody

Protein level used designations for CXCL16

chemokine (C-X-C motif) ligand 16 , C-X-C motif chemokine 16 , Transmembrane chemokine CXCL16 , Cxc chemokine ligand 16 , SR-PSOX/CXCL16 , scavenger receptor for phosphatidylserine and oxidized low density lipoprotein , small-inducible cytokine B16 , transmembrane chemokine CXCL16 , zinc finger, MYND-type containing 15 , CXC chemokine ligand 16

GENE ID SPECIES
454451 Pan troglodytes
607514 Canis lupus familiaris
396735 Sus scrofa
66102 Mus musculus
58191 Homo sapiens
511671 Bos taurus
497942 Rattus norvegicus
101787378 Cavia porcellus
100348428 Oryctolagus cuniculus
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