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CXCR5 encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. Additionally we are shipping CXCR5 Antibodies (196) and CXCR5 Kits (14) and many more products for this protein.
Showing 6 out of 6 products:
miR (show MLXIP Proteins)-192 suppresses T follicular helper cell differentiation by targeting CXCR5 in childhood asthma.
basal CXCR5(+)Th17 cell frequency may indicate underlying differences in disease phenotype between patients and predict ultimate success of TNF (show TNF Proteins) inhibitor therapy
The A allele of rs613791 and G allele of rs523604 located in CXCR5 were observed to be significantly associated with vitiligo in the Chinese Han population.
These results provide clear evidence that CXCR4- or CCR5-beta-arrestin complexes induce receptor endocytosis and signaling in the absence of G protein coupling and ligand-induced conformational changes of the receptor.
these findings demonstrate that CXCR5 overexpression increases the ability of MSCs to respond to migratory stimuli and highly intensifies their immunomodulatory effects in vivo. This strategy for enhancing targeted stem/progenitor cell homing may improve the efficacy of MSC (show MSC Proteins)-based therapies.
all three p53 (show TP53 Proteins) family members mediate the effects of genotoxic stress on the CXCR5 promoter using the same mechanism associated with attenuation of NFkB activity.
identified the miR (show MLXIP Proteins)-19a/CXCR5 pathway as a candidate p53 (show TP53 Proteins)-induced migration mechanism
CXCL13 (show CXCL13 Proteins)/CXCR5 mediated the aggregation of B cells, that directed the aberrant humoral immune responses via the formation of ectopic germinal centers, which suggests a molecular mechanism of neurological damage in neurosyphilis.
the data demonstrate that CXCR5(+)CD8 (show CD8A Proteins)(+) T cells represent a significant CD8 (show CD8A Proteins)(+) T cell subset in colorectal tumors and have the potential to contribute to antitumor immunity, but their specific roles require further studies in vivo.
we demonstrate that PKCepsilon (show PRKCE Proteins) cooperates with the loss of the tumor suppressor Pten for the development of prostate cancer in a mouse model. Mechanistic analysis revealed that PKCe (show PRKCE Proteins) overexpression and Pten loss individually and synergistically upregulate the production of the chemokine (show CCL1 Proteins) CXCL13 (show CXCL13 Proteins), which involves the transcriptional activation of the CXCL13 (show CXCL13 Proteins) gene
CXCR5 role in the inflammatory pain.CXCL13, upregulated by peripheral inflammation, acts on CXCR5 on dorsal root ganglia neurons and activates p38 (show CRK Proteins), which increases Nav1.8 (show SCN10A Proteins) current density and further contributes to the maintenance of inflammatory pain.
CXCL13 (show CXCL13 Proteins) acts on CXCR5 to increase p38 (show CRK Proteins) activation and further contributes to the pathogenesis of orofacial neuropathic pain
Cxcr5(CreERT2)R26(Tomato) mice are a useful tool for studying the cell fate of differentiated follicular helper T cells in vivo
CXCL13 (show CXCL13 Proteins) and CXCR5 contribute to orofacial pain via ERK (show EPHB2 Proteins)-mediated proinflammatory cytokines production.
Cxcr5 role in the protection of retinal pigment epithelium and retinal cells during aging and Cxcr5 loss may lead to age-related macular degeneration like pathological changes in aged mice.
These data suggest that CXCR5-expressing conventional dendritic cells play an important role in the efficient propagation of orally administered prions toward follicular dendritic cells within Peyer's patches in order to establish host infection.
CXCR5 is involved critically in B cell trafficking and germinal cell formation in murine lupus and in guiding pathogenic double-negative T cells into lymphoid organs and kidneys.
The importance of CXCR5 in autoimmune arthritis varies depending on environmental circumstances.
findings reveal a neuronal/astrocytic interaction in the spinal cord by which neuronally produced CXCL13 (show CXCL13 Proteins) activates astrocytes via CXCR5 to facilitate neuropathic pain.
IL-33 (show IL33 Proteins) enhances humoral immunity against chronic hbv infection through activating CD4 (show CD4 Proteins)(+)CXCR5(+) helper-Inducer T-Lymphocytes.
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
, C-X-C chemokine receptor type 5
, chemokine receptor
, Burkitt lymphoma receptor 1
, chemokine (C-X-C motif) receptor 5
, c-X-C chemokine receptor type 5-like
, Burkitt lymphoma receptor 1, GTP-binding protein
, monocyte-derived receptor 15
, burkitt lymphoma receptor 1 homolog
, chemochine (C-X-C motif) receptor 5
, neurolymphatic receptor