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C9orf3 encodes a member of the M1 zinc aminopeptidase family.
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HPV-16 E6 was confirmed to regulate microRNA miR-23b indirectly through the DNA methylation of host gene C9orf3 and thus induce c-MET and inhibit apoptosis in cervical cancer cells.
Data suggest that aminopeptidase O could play a role in the proteolytic processing of bioactive peptides in those tissues where it is expressed.
decreased miRNA-27b regulates the activity of the CCL20/CCR6 axis by targeting Naa15, and promotes plaque stability in atherosclerosis
MiRNA-27b regulates mitochondria biogenesis in myocytes by down-regulation of Foxj3 during myocyte differentiation.
These results indicate that miR (show MLXIP ELISA Kits)-27b functions as a central target of glucocorticoids and as an upstream regulator of Prdm16 (show PRDM16 ELISA Kits).
Alternative splicing predictably produces protein products with or without the catalytic domain and/or a nucleolar localisation signal and represents mechanism in regulating activity of APO.
This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants.
chromosome 9 open reading frame 3
, aminopeptidase O
, hypothetical protein LOC100145347