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Cleavage and Polyadenylation Specific Factor 4, 30kDa Proteins

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain.

7 results:

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-269) protein (His tag) Protein

CPSF4 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3078096
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-211) protein (His tag) Protein

CPSF4 Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3125158
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) Protein Protein

CPSF4 Origin: Human Source: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Catalog No. ABIN2128680
$474.43
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-244) protein (GST tag) Protein

CPSF4 Origin: Human Source: Wheat germ Recombinant AA, AP, ELISA, WB
Catalog No. ABIN1350238
$338.33
Plus shipping costs $45.00 and $22.00 dry ice
2 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) protein (His tag) Protein

CPSF4 Origin: Human Source: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN1098798
$553.85
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 15 to 19 Business Days

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-243) protein (His tag) Protein

CPSF4 Origin: Rat Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1630471
$2,619.83
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-243) protein (His tag) Protein

CPSF4 Origin: Cow Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1461037
$2,619.83
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days
  • Type Protein
    • Protein
  • Target Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
    • Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Thymidylate Kinase (Tmk)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Leptin (LEP)
    • Epidermal Growth Factor (EGF)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Interleukin 8 (IL8)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Albumin (ALB)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Interleukin 15 (IL15)
    • beta-2-Microglobulin (B2M)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Gp120
    • Interleukin 33 (IL33)
    • Transforming Growth Factor, beta 1 (TGFB1)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • Reactivity
    • Human
    • Cow
    • Mouse
    • Rat
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • Insect Cells
    • Yeast
    • Wheat germ
  • Binding Specificity
    • AA 1-243
    • AA 1-211
    • AA 1-244
    • AA 1-269
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) Protein Profile

Protein Summary

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene names and symbols associated with CPSF4

  • cleavage and polyadenylation specific factor 4 (CPSF4) antibody
  • cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4) antibody
  • cleavage and polyadenylation specific factor 4 (LOC733099) antibody
  • cleavage and polyadenylation specific factor 4 (LOC100360200) antibody
  • cleavage and polyadenylation specific factor 4 S homeolog (cpsf4.S) antibody
  • cleavage and polyadenylation specific factor 4 (cpsf4) antibody
  • cleavage and polyadenylation specific factor 4 (Cpsf4) antibody
  • 30kDa antibody
  • C79664 antibody
  • CPSF30 antibody
  • NAR antibody
  • NEB1 antibody

Protein level used designations for CPSF4

no arches , GLEAN_10339 , cleavage and polyadenylation specific factor 4 , cleavage and polyadenylation specificity factor subunit 4 , cleavage and polyadenylation specific factor 4, 30kDa , CPSF 30 kDa subunit , cleavage and polyadenylation specific factor 4, 30kD subunit , cleavage and polyadenylation specificity factor 30 kDa subunit , clipper homolog , clipper/CPSF 30K , musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit , NS1 effector domain-binding protein 1 , cleavage-polyadenylation specificity factor, 30kD , neb-1 , no arches homolog , no arches-like zinc finger protein , cleavage-polyadenylation specificity factor, 30 kD

GENE ID SPECIES
463572 Pan troglodytes
660072 Tribolium castaneum
733099 Bombyx mori
100360200 Rattus norvegicus
444766 Xenopus laevis
493312 Xenopus (Silurana) tropicalis
708119 Macaca mulatta
100224162 Taeniopygia guttata
54188 Mus musculus
304277 Rattus norvegicus
10898 Homo sapiens
416494 Gallus gallus
489859 Canis lupus familiaris
280875 Bos taurus
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