anti-Cluster of Differentiation 1e (CD1e) Antibodies

CD1e encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. Additionally we are shipping Cluster of Differentiation 1e Proteins (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD1e 913 P15812
CD1e    
CD1e    
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Top anti-Cluster of Differentiation 1e Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB CD1E Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of CD1E Antibody (Center)(Cat#AP50840PU-N) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Pancreas, antibody was diluted at 1:100. 100 μL Log in to see Available
$363.46
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of CD1e staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of CD1e expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB CD1E Antibody (Center) (ABIN653900) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane).This demonstrates the CD1E antibody detected the CD1E protein (arrow). CD1E Antibody (Center) (ABIN653900) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see Available
$363.46
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded glioma tissue 100 μg Log in to see 15 to 18 Days
$332.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6275622 staining  HepG2 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with CD1E polyclonal antibody  shows moderate cytoplasmic positivity in subset of non-germinal center cells. Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart muscle with CD1E polyclonal antibody  shows moderate to strong cytoplasmic positivity in myocytes. 100 μL Log in to see 11 to 12 Days
$577.33
Details
Human Mouse Un-conjugated CyTOF, FACS Detection of CD1e in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was treated for 3 hours with monensin, then stained with Mouse Anti-Human CD1e Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 8 to 9 Days
$238.43
Details

More Antibodies against Cluster of Differentiation 1e Interaction Partners

Human Cluster of Differentiation 1e (CD1e) interaction partners

  1. Single nucleotide polymorphisms in exon 2 of CD1A (*01/*02) and CD1E (*01/*02) cannot be recognized as a susceptibility or disease-causative factor for Guillain-Barre syndrome in the Bangladeshi population

  2. There was no association between polymorphisms of CD1E genes and the susceptibilities to Guillain-Barre syndrome.

  3. for isoforms CD1b through CD1e, our simulations show the near-complete collapse of the hydrophobic cavities in the absence of the antigen. This event results from the spontaneous closure of the binding domain entrance, flanked by two alpha-helices.

  4. The interaction of LAPTM5 with CD1e and their colocalization in antigen processing compartments both suggest that LAPTM5 might influence the role of CD1e in the presentation of lipid antigens.

  5. Deciphering the role of CD1e protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM) processing for presentation by CD1b to T lymphocytes

  6. in the late endosomes/lysosomes of dendritic cells, the acid pH promotes the binding of lipid antigens to CD1e through increased hydrophobic and ionic interactions

  7. allelic variation in CD1E does not play a major role in determining multifocal motor neuropathy susceptibility.

  8. In Guillain-Barre syndrome, an initially positive association study with polymorphism of CD1A and CD1E genes was not confirmed

  9. CD1e may positively or negatively affect lipid presentation by CD1b, CD1c, and CD1d.

  10. These data support that CD1e could have evolved to mediate lipid-exchange/editing processes.

  11. CD1A and CD1E polymorphisms contribute to the polygenic susceptibility to multiple sclerosis

  12. CD1E and CD1A genes may be involved in networks which determine susceptibility to multiple sclerosis types RR-MS and PP-MS, respectively.

  13. substitutions lead to amino acid changes at position 73 and 77 of the alpha1 domain in the former and at position 30 of the alpha2 domain in the latter suggesting that the CD1E gene is much more polymorphic than previously assumed.

  14. cellular and biochemical properties of the human and simian CD1e molecules are similar, suggesting that the particular intracellular distribution of CD1e is important for its physiological and/or immunological function

  15. required for processing of the mycobcterial antigens hexamannosylated phosphatidyl-myo-inositols(PIM6); propose that, through this form of glycolipid editing, CD1e helps expand the repertoire of glycolipidic T cell antigens to optimize immune response

  16. Data show that ubiquitination of CD1e appears to trigger its exit from Golgi compartments and its transport to endosomes.

  17. A polymorphism related to the capacity of the CD1E molecule to participate in the immune response to complex glycolipids is discovered in individuals who might display a CD1e-altered immune response to complex glycolipid antigens.

  18. SNPs in CD1A and CD1E were not associated with GBS susceptibility, specific clinical subgroups, anti-ganglioside antibodies, antecedent infections and prognosis.

  19. CD1e propeptide is conserved during evolution, suggesting that it may also optimize the generation of CD1e molecules in other species.

Cluster of Differentiation 1e (CD1e) Antigen Profile

Protein Summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found\; however, their biological validity has not been determined.

Gene names and symbols associated with CD1e

  • CD1e molecule (CD1E) antibody
  • CD1e molecule (Cd1e) antibody
  • CD1-e antibody
  • CD1A antibody
  • R2 antibody

Protein level used designations for CD1e

CD1E antigen, e polypeptide , R2G1 , T-cell surface glycoprotein CD1e, membrane-associated , differentiation antigen CD1-alpha-3 , hCD1e , leukocyte differentiation antigen , thymocyte antigen CD1E , T-cell surface glycoprotein CD1e, soluble , mCD1e

GENE ID SPECIES
913 Homo sapiens
100379271 Cavia porcellus
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