Clusterin Associated Protein 1 Proteins (CLUAP1)

The protein encoded by CLUAP1 contains a single coiled-coil region. Additionally we are shipping Clusterin Associated Protein 1 Antibodies (36) and Clusterin Associated Protein 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CLUAP1 23059 Q96AJ1
CLUAP1 76779 Q8R3P7
Rat CLUAP1 CLUAP1 363544 Q6AYJ5
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Top Clusterin Associated Protein 1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$460.85
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 60 to 71 Days
$3,151.50
Details
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$3,191.83
Details

CLUAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

More Proteins for Clusterin Associated Protein 1 (CLUAP1) Interaction Partners

Human Clusterin Associated Protein 1 (CLUAP1) interaction partners

  1. Two variants in CLUAP1 were identified through exome-sequence analysis, Chr16:g.3558407T>G, c.338T>G, p.(Met113Arg) and Chr16:g.3570011C>T, c.688C>T, p.(Arg230Ter). he genetic data show that these variants are present in an affected child, are rare in the population, and result in reduced, but not absent, intraflagellar transport.

  2. Consistent with the knowledge that CLUAP1 plays an important role in cilia function and that cilia are critical to photoreceptor function, our results indicate that hypomorphic mutations in CLUAP1 can result in dysfunctional photoreceptors without systemic abnormalities. This is the first report linking mutations in CLUAP1 to human disease and establishes CLUAP1 as a candidate Leber congenital amaurosis gene

  3. inactivation of CLUAP1 may conceivably serve in the future as a novel therapeutic intervention for treatment of colon cancer

  4. CLUAP1 (clusterin-associated protein 1) is highly expressed in osteosarcoma, ovarian, colon, and lung cancers

Mouse (Murine) Clusterin Associated Protein 1 (CLUAP1) interaction partners

  1. a ciliogenesis defect of Cluap1-deficient embryonic fibroblasts was rescued by exogenous expression of wild-type Cluap1 but not by mutant Cluap1 lacking the binding ability to other IFT-B components

  2. Cluap1 contributes to ciliogenesis by regulating the intraflagellar transport cycle at the base and tip of the cilium

Zebrafish Clusterin Associated Protein 1 (CLUAP1) interaction partners

  1. Consistent with the knowledge that CLUAP1 plays an important role in cilia function and that cilia are critical to photoreceptor function, our results indicate that hypomorphic mutations in CLUAP1 can result in dysfunctional photoreceptors without systemic abnormalities. This is the first report linking mutations in CLUAP1 to human disease and establishes CLUAP1 as a candidate Leber congenital amaurosis gene

  2. We identified a novel mutation in cluap1 and determined that photoreceptor maintenance is dependent on cluap1.

Clusterin Associated Protein 1 (CLUAP1) Protein Profile

Protein Summary

The protein encoded by this gene contains a single coiled-coil region. Alternative splicing results in multiple transcript variants and protein isoforms.

Gene names and symbols associated with CLUAP1

  • clusterin associated protein 1 (CLUAP1)
  • clusterin associated protein 1 (cluap1)
  • clusterin associated protein 1 L homeolog (cluap1.L)
  • clusterin associated protein 1 (Cluap1)
  • 2310030D15Rik protein
  • 2610111M03Rik protein
  • CLUAP1 protein
  • FAP22 protein
  • fj16b11 protein
  • MGC99254 protein
  • wu:fj16b11 protein
  • zgc:56115 protein

Protein level used designations for CLUAP1

clusterin associated protein 1 , clusterin-associated protein 1 , flagellar associated protein 22, qilin-like protein, homolog , qilin , clusterin-associated protein 1 homolog , qil

GENE ID SPECIES
467890 Pan troglodytes
549723 Xenopus (Silurana) tropicalis
617589 Bos taurus
703676 Macaca mulatta
779379 Xenopus laevis
100595637 Nomascus leucogenys
23059 Homo sapiens
76779 Mus musculus
426077 Gallus gallus
479868 Canis lupus familiaris
100514829 Sus scrofa
363544 Rattus norvegicus
406281 Danio rerio
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